iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035922

Ensembl Protein ID

ENSFCAP00000008002.3

UniProt Accession

M3W9X6; M3W9X6_FELCA

Genbank Protein ID

ENSFCAP00000008002

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AANG02051749

Gene Name

KMT2C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000008632.3	ENSFCAT00000008634.3	ENSFCAP00000008002.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.40e-29	99.6	1017	1068

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
           +C+vC +++++e+ +++C++C++w+H+ C +l+ eee++n  +  + C+ Cr
   Q: 1017 SCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADigFDCSMCR 1068
           6********************************999999998899******8 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MDGLETTETE NIVETAEIKE QSAEEDAEAE VDISKRPVPV LERSVSEDSA SSLVSVGVEV 60
KISEQLCAFC YCGEKSSLGQ GDLKQFRVTP GFILPWKSQP FNKKDIDDSS NGTCDKIQNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTTCTATA TAGGCCTCGA AGTAGAGGAA AAATTACAGT GGAAGATGAG GACAGCATGG 60
ATGGACTGGA GACAACAGAA ACAGAAAATA TTGTGGAAAC AGGTATCAAA CTTAACAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	91.26	0.00e+00	7551.00
IUUC-Apl-003311	Anas platyrhynchos	71.46	0.00e+00	5598.00
IUUC-Aca-004705	Anolis carolinensis	65.56	0.00e+00	5179.00
IUUC-Bta-012322	Bos taurus	84.30	0.00e+00	6731.00
IUUC-Cel-018354	Caenorhabditis elegans	35.67	3.00e-64	241.00
IUUC-Cja-019983	Callithrix jacchus	85.24	0.00e+00	7136.00
IUUC-Cfa-020903	Canis familiaris	89.47	0.00e+00	7521.00
IUUC-Cpo-021732	Cavia porcellus	80.38	0.00e+00	6623.00
IUUC-Csa-023083	Chlorocebus sabaeus	83.46	0.00e+00	5297.00
IUUC-Cho-024469	Choloepus hoffmanni	79.71	0.00e+00	2179.00
IUUC-Cme-027224	Cyanidioschyzon merolae	36.71	2.00e-11	64.70
IUUC-Dre-028110	Danio rerio	64.10	0.00e+00	1239.00
IUUC-Dor-030569	Dipodomys ordii	78.20	0.00e+00	4307.00
IUUC-Dme-031590	Drosophila melanogaster	33.40	9.00e-70	259.00
IUUC-Eca-033945	Equus caballus	86.96	0.00e+00	5214.00
IUUC-Gac-041896	Gasterosteus aculeatus	45.66	0.00e+00	1800.00
IUUC-Ggo-044812	Gorilla gorilla	83.51	0.00e+00	6996.00
IUUC-Hsa-046595	Homo sapiens	85.69	0.00e+00	7174.00
IUUC-Itr-048303	Ictidomys tridecemlineatus	83.77	0.00e+00	6746.00
IUUC-Lch-050086	Latimeria chalumnae	56.67	0.00e+00	2601.00
IUUC-Loc-052891	Lepisosteus oculatus	51.84	0.00e+00	1877.00
IUUC-Laf-054348	Loxodonta africana	81.90	0.00e+00	2978.00
IUUC-Mcc-054868	Macaca mulatta	85.88	0.00e+00	7133.00
IUUC-Meu-056322	Macropus eugenii	65.55	0.00e+00	1134.00
IUUC-Mga-059541	Meleagris gallopavo	70.84	0.00e+00	5468.00
IUUC-Mmr-061092	Microcebus murinus	83.49	0.00e+00	5320.00
IUUC-Mdo-062610	Monodelphis domestica	75.96	0.00e+00	2067.00
IUUC-Mmu-063666	Mus musculus	81.32	0.00e+00	6667.00
IUUC-Mpu-066366	Mustela putorius furo	88.73	0.00e+00	6930.00
IUUC-Mlu-068201	Myotis lucifugus	84.16	0.00e+00	6722.00
IUUC-Nle-069232	Nomascus leucogenys	83.11	0.00e+00	5292.00
IUUC-Opr-070625	Ochotona princeps	76.05	0.00e+00	1294.00
IUUC-Ont-072401	Oreochromis niloticus	57.07	0.00e+00	1038.00
IUUC-Oan-072945	Ornithorhynchus anatinus	70.88	0.00e+00	4104.00
IUUC-Ocu-074920	Oryctolagus cuniculus	81.25	0.00e+00	5177.00
IUUC-Ola-086436	Oryzias latipes	44.62	0.00e+00	1790.00
IUUC-Oga-088637	Otolemur garnettii	81.09	0.00e+00	4194.00
IUUC-Oar-089363	Ovis aries	82.50	0.00e+00	6544.00
IUUC-Ptr-091527	Pan troglodytes	85.63	0.00e+00	7219.00
IUUC-Pan-092102	Papio anubis	83.44	0.00e+00	6886.00
IUUC-Pma-094252	Petromyzon marinus	40.71	2.00e-164	574.00
IUUC-Pfo-096288	Poecilia formosa	60.49	0.00e+00	1146.00
IUUC-Pab-098241	Pongo abelii	84.65	0.00e+00	4548.00
IUUC-Pca-100103	Procavia capensis	80.92	0.00e+00	1587.00
IUUC-Pva-102238	Pteropus vampyrus	78.21	0.00e+00	2604.00
IUUC-Rno-105395	Rattus norvegicus	72.41	0.00e+00	1076.00
IUUC-Sha-106550	Sarcophilus harrisii	71.16	0.00e+00	4335.00
IUUC-Sar-113183	Sorex araneus	67.36	0.00e+00	688.00
IUUC-Tgu-116677	Taeniopygia guttata	70.88	0.00e+00	5313.00
IUUC-Tru-118037	Takifugu rubripes	52.83	0.00e+00	1269.00
IUUC-Tsy-118932	Tarsius syrichta	84.42	0.00e+00	5083.00
IUUC-Tni-119970	Tetraodon nigroviridis	53.16	0.00e+00	1274.00
IUUC-Ttr-129051	Tursiops truncatus	84.08	0.00e+00	6652.00
IUUC-Vpa-130236	Vicugna pacos	82.74	0.00e+00	1934.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence