iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026857

Ensembl Protein ID

AAW43269

UniProt Accession

Q5KIA2; Q5KIA2_CRYNJ

Genbank Protein ID

AAW43269.2

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AE017344

Gene Name

CND03680

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CND03680	AAW43269	AAW43269

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.80e-75	251.1	1475	1841

Active Site

Position(s)	Description	Evidence
1915	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp...........ehlklFeflGrllgkalqdgrlldlpl 92
           +   leve+ +E g++l G+t+ef+al ske+ + +l  ++ ++ + + +++    gl +             +lk+F+ lG+++g ++ d+r++d+ +
   Q: 1475 FPGTLEVEYFDEIGTGL-GPTLEFYALASKEFARRNLHVWRDEDPSIAGNYVHHPHGLFPSplprasaelvaSRLKWFKTLGQFIGRSMLDSRIIDISF 1572
           56789************.**********************998887777777777776554799*********************************** PP
   S: 93   sksfyklllgk..klsledleevdpelykslkeikena......es..................dieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +k+f+klll+k  k +l+ l +vdp l++sl+ ++ +       e+                  d + ++l+l f+     l+ ++ e LkpgG++i+V
   Q: 1573 NKVFLKLLLDKpiKKNLSTLRAVDPSLARSLERLQGYYcvrkeiEAlpipassrrtklaaltvgDAKLADLALDFT-----LPGYDIE-LKPGGAHIEV 1665
           ***********4434679*****************99877766611555555556666666666666666677776.....5666555.********** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerka 263
             +N+ eY ++v++++l +g++eqv+af++Gf++++p++++++F+  el ll     e+++ e+l+  +k ++gy++ds+a+q+++ev+++ ++e+r++
   Q: 1666 DDSNLGEYLEKVLDWTLGSGVAEQVKAFQDGFSSIFPIKSIKIFSLDELYLLFGNAdEDWSRETLEVAIKADHGYNQDSRAVQNLIEVMSSYNKEQRRQ 1764
           *************************************************87766657899999999999****************************** PP
   S: 264  fLqFvTgssrlPlgGfaelkprlfvirk.....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
           fLqF+Tg ++lP+gGf+ l p ++v+rk     +++dd lPs++TC+ yLk+P+Ysske+l  +   A++ +  +F 
   Q: 1765 FLQFMTGAPKLPIGGFRGLTPPFTVVRKpheppYKADDYLPSVMTCALYLKMPDYSSKEVLAAQFERAMRDGrGSFL 1841
           *********************************9*****************************99999998866675 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MHNQGLPSYP EWIKVGPVNV TIATATTTFQ FIDTWPRNRS QRQKARYSAV ILRGDTSNEK 60
AKAPITHQRS AARHLVSDEY DDEDDSLWID EPEGDVTVAE ESDMADDYDH EEDDEDDEDG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACAACC AAGGGCTCCC TTCGTATCCT GAATGGATCA AGGTGGGGCC TGTGAACGTC 60
ACCATTGCTG TTCGTCTTCG ATACTTTTCA TTCAAAGCTA GACGAAGCGA GGTGTCCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

cne:CND03680

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	38.73	8.00e-101	360.00
IUUC-Aml-001502	Ailuropoda melanoleuca	39.93	1.00e-102	367.00
IUUC-Atr-002821	Amborella trichopoda	38.14	1.00e-96	346.00
IUUC-Apl-003531	Anas platyrhynchos	38.31	1.00e-94	340.00
IUUC-Aca-004521	Anolis carolinensis	32.31	5.00e-31	129.00
IUUC-Aly-005962	Arabidopsis lyrata	37.22	4.00e-97	348.00
IUUC-Ath-006636	Arabidopsis thaliana	37.22	2.00e-97	349.00
IUUC-Ago-007875	Ashbya gossypii	40.33	3.00e-111	395.00
IUUC-Acl-008242	Aspergillus clavatus	44.43	4.00e-157	548.00
IUUC-Afl-008736	Aspergillus flavus	45.06	1.00e-156	546.00
IUUC-Afu-008812	Aspergillus fumigatus	46.22	1.00e-154	539.00
IUUC-Ani-009407	Aspergillus nidulans	45.69	2.00e-158	551.00
IUUC-Ang-009763	Aspergillus niger	43.99	7.00e-144	503.00
IUUC-Aor-009941	Aspergillus oryzae	46.21	1.00e-154	539.00
IUUC-Ate-010459	Aspergillus terreus	42.83	2.00e-133	468.00
IUUC-Ame-011761	Astyanax mexicanus	39.54	1.00e-101	363.00
IUUC-Bgr-012265	Blumeria graminis	42.38	3.00e-148	518.00
IUUC-Bta-013070	Bos taurus	39.67	2.00e-102	366.00
IUUC-Bci-013890	Botrytis cinerea	44.41	9.00e-149	520.00
IUUC-Bdi-014046	Brachypodium distachyon	37.08	4.00e-100	358.00
IUUC-Bol-015942	Brassica oleracea	36.46	2.00e-96	346.00
IUUC-Bra-016849	Brassica rapa	36.81	1.00e-96	347.00
IUUC-Cel-018153	Caenorhabditis elegans	31.89	3.00e-72	266.00
IUUC-Cja-019046	Callithrix jacchus	39.93	2.00e-102	366.00
IUUC-Cfa-020521	Canis familiaris	39.59	3.00e-102	365.00
IUUC-Cpo-021639	Cavia porcellus	39.93	3.00e-102	365.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	38.03	2.00e-90	324.00
IUUC-Csa-023231	Chlorocebus sabaeus	39.93	2.00e-102	366.00
IUUC-Cho-024380	Choloepus hoffmanni	41.15	3.00e-86	312.00
IUUC-Cin-025482	Ciona intestinalis	35.34	8.00e-90	322.00
IUUC-Csv-026121	Ciona savignyi	35.50	1.00e-88	320.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	45.67	4.00e-157	548.00
IUUC-Cme-027226	Cyanidioschyzon merolae	34.02	1.00e-68	253.00
IUUC-Dre-028174	Danio rerio	39.54	3.00e-101	362.00
IUUC-Dno-029954	Dasypus novemcinctus	31.15	5.00e-30	126.00
IUUC-Dor-030939	Dipodomys ordii	35.63	4.00e-80	291.00
IUUC-Dse-031444	Dothistroma septosporum	45.16	5.00e-165	574.00
IUUC-Dme-031739	Drosophila melanogaster	31.66	3.00e-75	276.00
IUUC-Ete-032345	Echinops telfairi	33.40	3.00e-71	262.00
IUUC-Eca-033229	Equus caballus	39.93	3.00e-102	365.00
IUUC-Eeu-035205	Erinaceus europaeus	39.93	2.00e-101	363.00
IUUC-Fca-036444	Felis catus	39.93	2.00e-102	366.00
IUUC-Fal-037131	Ficedula albicollis	40.11	4.00e-104	372.00
IUUC-Fox-038035	Fusarium oxysporum	45.84	1.00e-152	531.00
IUUC-Fso-038320	Fusarium solani	45.38	5.00e-158	550.00
IUUC-Gmo-039497	Gadus morhua	41.06	7.00e-102	364.00
IUUC-Ggr-040057	Gaeumannomyces graminis	44.52	6.00e-159	553.00
IUUC-Gga-041021	Gallus gallus	39.93	1.00e-103	370.00
IUUC-Gac-042474	Gasterosteus aculeatus	40.19	2.00e-102	365.00
IUUC-Gma-043048	Glycine max	38.46	1.00e-101	363.00
IUUC-Ggo-044855	Gorilla gorilla	39.93	2.00e-102	366.00
IUUC-Hsa-046147	Homo sapiens	39.93	3.00e-102	365.00
IUUC-Hvu-047775	Hordeum vulgare	38.20	1.00e-98	353.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	39.93	5.00e-102	364.00
IUUC-Kpa-049098	Komagataella pastoris	42.36	2.00e-117	416.00
IUUC-Lch-049818	Latimeria chalumnae	38.86	9.00e-98	350.00
IUUC-Lpe-051017	Leersia perrieri	36.33	3.00e-93	335.00
IUUC-Loc-051777	Lepisosteus oculatus	40.30	4.00e-103	368.00
IUUC-Lma-052990	Leptosphaeria maculans	44.09	7.00e-156	543.00
IUUC-Laf-053727	Loxodonta africana	39.85	1.00e-102	366.00
IUUC-Mcc-055799	Macaca mulatta	39.93	2.00e-102	366.00
IUUC-Meu-056065	Macropus eugenii	37.24	4.00e-79	288.00
IUUC-Mor-057054	Magnaporthe oryzae	44.09	3.00e-159	554.00
IUUC-Mpo-057417	Magnaporthe poae	44.94	2.00e-164	572.00
IUUC-Mtr-057849	Medicago truncatula	40.00	2.00e-100	359.00
IUUC-Mla-058870	Melampsora laricipopulina	44.64	5.00e-148	517.00
IUUC-Mga-059580	Meleagris gallopavo	27.18	2.00e-54	206.00
IUUC-Mvi-060507	Microbotryum violaceum	46.09	2.00e-163	569.00
IUUC-Mmr-060816	Microcebus murinus	40.30	9.00e-102	364.00
IUUC-Mdo-062866	Monodelphis domestica	37.58	3.00e-80	292.00
IUUC-Mmu-063906	Mus musculus	39.74	1.00e-101	363.00
IUUC-Mac-064675	Musa acuminata	37.06	1.00e-93	335.00
IUUC-Mpu-066199	Mustela putorius furo	39.74	5.00e-102	364.00
IUUC-Mlu-067110	Myotis lucifugus	39.93	2.00e-101	363.00
IUUC-Nfi-068482	Neosartorya fischeri	46.05	3.00e-154	538.00
IUUC-Ncr-068906	Neurospora crassa	45.62	2.00e-160	558.00
IUUC-Nle-069410	Nomascus leucogenys	39.93	2.00e-102	366.00
IUUC-Opr-070401	Ochotona princeps	38.71	4.00e-47	182.00
IUUC-Ont-072100	Oreochromis niloticus	40.18	3.00e-104	372.00
IUUC-Oan-073121	Ornithorhynchus anatinus	39.59	8.00e-102	364.00
IUUC-Ocu-074623	Oryctolagus cuniculus	39.93	1.00e-102	367.00
IUUC-Oba-075380	Oryza barthii	34.09	4.00e-89	321.00
IUUC-Obr-076915	Oryza brachyantha	36.44	9.00e-94	337.00
IUUC-Ogl-077055	Oryza glaberrima	36.54	4.00e-93	335.00
IUUC-Ogu-078892	Oryza glumaepatula	34.24	7.00e-90	323.00
IUUC-Oin-079256	Oryza indica	36.16	3.00e-91	328.00
IUUC-Olo-080343	Oryza longistaminata	36.16	3.00e-91	328.00
IUUC-Ome-081422	Oryza meridionalis	36.16	6.00e-91	328.00
IUUC-Oni-083047	Oryza nivara	34.24	1.00e-91	329.00
IUUC-Opu-083641	Oryza punctata	34.03	8.00e-91	327.00
IUUC-Oru-084439	Oryza rufipogon	34.24	7.00e-90	323.00
IUUC-Osa-085972	Oryza sativa	36.54	4.00e-92	330.00
IUUC-Ola-087173	Oryzias latipes	39.35	3.00e-102	365.00
IUUC-Olu-087871	Ostreococcus lucimarinus	37.24	1.00e-94	338.00
IUUC-Oga-087908	Otolemur garnettii	39.93	3.00e-102	365.00
IUUC-Oar-090277	Ovis aries	39.67	1.00e-102	367.00
IUUC-Ptr-091543	Pan troglodytes	39.93	2.00e-102	366.00
IUUC-Pan-092243	Papio anubis	40.11	8.00e-103	367.00
IUUC-Psi-093150	Pelodiscus sinensis	39.81	3.00e-102	365.00
IUUC-Pno-094891	Phaeosphaeria nodorum	45.38	8.00e-159	553.00
IUUC-Ppa-095181	Physcomitrella patens	39.76	3.00e-95	340.00
IUUC-Pfo-096267	Poecilia formosa	40.42	7.00e-103	367.00
IUUC-Pab-098072	Pongo abelii	39.93	2.00e-102	366.00
IUUC-Pop-099190	Populus trichocarpa	37.26	1.00e-100	360.00
IUUC-Pca-100311	Procavia capensis	39.85	2.00e-102	366.00
IUUC-Ppe-101284	Prunus persica	37.33	4.00e-100	358.00
IUUC-Pva-102215	Pteropus vampyrus	37.31	2.00e-90	326.00
IUUC-Pgr-103694	Puccinia graminis	45.99	2.00e-157	549.00
IUUC-Ptt-103916	Puccinia triticina	44.33	4.00e-148	518.00
IUUC-Pte-104346	Pyrenophora teres	44.01	4.00e-156	544.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	44.59	2.00e-158	551.00
IUUC-Rno-105315	Rattus norvegicus	39.93	4.00e-102	365.00
IUUC-Sce-106273	Saccharomyces cerevisiae	38.06	9.00e-98	350.00
IUUC-Sha-106835	Sarcophilus harrisii	39.59	2.00e-101	363.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	39.20	9.00e-121	426.00
IUUC-Spo-108081	Schizosaccharomyces pombe	41.39	3.00e-119	421.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	45.31	7.00e-154	536.00
IUUC-Smo-108776	Selaginella moellendorffii	38.65	5.00e-95	341.00
IUUC-Sit-109757	Setaria italica	36.90	3.00e-99	355.00
IUUC-Sly-111469	Solanum lycopersicum	37.17	6.00e-98	351.00
IUUC-Stu-112896	Solanum tuberosum	36.81	7.00e-85	306.00
IUUC-Sar-113224	Sorex araneus	41.89	3.00e-80	292.00
IUUC-Sbi-114313	Sorghum bicolor	37.93	1.00e-104	373.00
IUUC-Sre-114993	Sporisorium reilianum	40.61	1.00e-144	506.00
IUUC-Ssc-115535	Sus scrofa	36.50	1.00e-84	306.00
IUUC-Tgu-117493	Taeniopygia guttata	27.35	2.00e-54	206.00
IUUC-Tru-118669	Takifugu rubripes	40.49	9.00e-103	367.00
IUUC-Tsy-119373	Tarsius syrichta	33.48	9.00e-65	241.00
IUUC-Tni-120049	Tetraodon nigroviridis	34.65	5.00e-76	276.00
IUUC-Tca-121779	Theobroma cacao	36.94	3.00e-101	362.00
IUUC-Tre-122195	Trichoderma reesei	44.72	2.00e-153	535.00
IUUC-Tvi-122650	Trichoderma virens	43.48	8.00e-156	543.00
IUUC-Tae-123580	Triticum aestivum	38.26	7.00e-99	353.00
IUUC-Tur-126295	Triticum urartu	38.73	1.00e-101	363.00
IUUC-Tme-126964	Tuber melanosporum	43.96	9.00e-151	526.00
IUUC-Tbe-128149	Tupaia belangeri	38.55	6.00e-67	248.00
IUUC-Ttr-128165	Tursiops truncatus	39.93	1.00e-102	366.00
IUUC-Uma-129365	Ustilago maydis	36.60	4.00e-139	488.00
IUUC-Vda-129725	Verticillium dahliae	46.86	9.00e-150	523.00
IUUC-Vpa-130678	Vicugna pacos	39.93	2.00e-102	366.00
IUUC-Vvi-131147	Vitis vinifera	37.11	8.00e-99	354.00
IUUC-Xtr-132636	Xenopus tropicalis	39.54	2.00e-98	352.00
IUUC-Xma-133458	Xiphophorus maculatus	40.42	5.00e-103	368.00
IUUC-Yli-134481	Yarrowia lipolytica	42.04	1.00e-126	446.00
IUUC-Zma-135782	Zea mays	37.46	9.00e-101	360.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence