iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091313

UUCD1 version

UUC-PaT-00695

Ensembl Protein ID

ENSPTRP00000034414.3

UniProt Accession

H2QVX7; H2QVX7_PANTR

Genbank Protein ID

JAA06726.1; JAA13948.1; JAA26229.1; JAA38764.1

Protein Name

Tripartite motif containing 35

Genbank Nucleotide ID

AACZ03061077; GABF01008197; GABD01006871; GABE01005975

Gene Name

TRIM35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000020103.4	ENSPTRT00000037239.3	ENSPTRP00000034414.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.80e-07	30.5	21	61
E3 activity/RING/U-box	3.20e-09	36.7	16	85

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+C+++f+d  ++l+CgH f++ C+  +w     + + + +CP+C+
   Q: 21   CAVCYDPFRD-AVTLRCGHNFCRGCVsRCW-----EVQVSPTCPVCK 61
           ********99.999************9999.....799999*****6 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawcee 71
            ee+lC++ ++++rd v+l +G+ + r ++ ++ + + + tcPv++ + ++ dl  n+tl +l+++ + e
   Q: 16   KEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSpTCPVCKDRASPADLRTNHTLNNLVEKLLRE 85
           689******************************97766669**********************9987765 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MERSPDVSPG PSRSFKEELL CAVCYDPFRD AVTLRCGHNF CRGCVSRCWE VQVSPTCPVC 60
KDRASPADLR TNHTLNNLVE KLLREEAEGA RWTSYRFSRV CRLHRGQLSL FCLEDKELLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGGGTCGC AGGCGTTGGC AGCCGGGCGG GTGGGAGGGG CCGGAGCAAA AGTTCCGGGC 60
GCCCGAGCCG GCTGCTCGTG CCATGGAGCG GAGCCCCGAC GTGTCCCCCG GGCCTTCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	91.48	0.00e+00	941.00
IUUC-Apl-003958	Anas platyrhynchos	53.54	4.00e-133	468.00
IUUC-Aca-005199	Anolis carolinensis	47.52	3.00e-126	445.00
IUUC-Ame-011964	Astyanax mexicanus	36.33	7.00e-73	267.00
IUUC-Bta-013359	Bos taurus	88.98	0.00e+00	900.00
IUUC-Cja-018900	Callithrix jacchus	82.80	0.00e+00	843.00
IUUC-Cfa-020685	Canis familiaris	91.28	0.00e+00	940.00
IUUC-Cpo-022253	Cavia porcellus	81.54	0.00e+00	806.00
IUUC-Csa-023777	Chlorocebus sabaeus	99.59	0.00e+00	1019.00
IUUC-Dre-027686	Danio rerio	33.84	2.00e-59	223.00
IUUC-Dno-029065	Dasypus novemcinctus	85.74	0.00e+00	893.00
IUUC-Dor-030248	Dipodomys ordii	65.40	8.00e-103	366.00
IUUC-Ete-033183	Echinops telfairi	74.44	0.00e+00	733.00
IUUC-Eca-033263	Equus caballus	90.29	0.00e+00	819.00
IUUC-Eeu-034699	Erinaceus europaeus	80.75	4.00e-116	411.00
IUUC-Fca-036366	Felis catus	89.86	0.00e+00	926.00
IUUC-Fal-037257	Ficedula albicollis	56.58	4.00e-157	547.00
IUUC-Gmo-038512	Gadus morhua	35.37	3.00e-69	255.00
IUUC-Gga-041125	Gallus gallus	54.81	1.00e-106	379.00
IUUC-Gac-042136	Gasterosteus aculeatus	35.31	8.00e-71	260.00
IUUC-Ggo-045233	Gorilla gorilla	100.00	0.00e+00	653.00
IUUC-Hsa-046042	Homo sapiens	100.00	0.00e+00	1021.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	91.67	0.00e+00	921.00
IUUC-Lch-049548	Latimeria chalumnae	35.12	9.00e-82	297.00
IUUC-Loc-051729	Lepisosteus oculatus	35.89	2.00e-82	299.00
IUUC-Laf-054322	Loxodonta africana	90.79	0.00e+00	911.00
IUUC-Mcc-055555	Macaca mulatta	97.39	0.00e+00	1000.00
IUUC-Meu-055900	Macropus eugenii	80.46	0.00e+00	804.00
IUUC-Mga-059380	Meleagris gallopavo	56.23	2.00e-105	375.00
IUUC-Mmr-061296	Microcebus murinus	92.09	0.00e+00	935.00
IUUC-Mdo-062811	Monodelphis domestica	80.50	0.00e+00	804.00
IUUC-Mmu-063718	Mus musculus	79.42	0.00e+00	806.00
IUUC-Mpu-066219	Mustela putorius furo	90.44	0.00e+00	909.00
IUUC-Mlu-067033	Myotis lucifugus	85.77	0.00e+00	885.00
IUUC-Nle-069806	Nomascus leucogenys	99.13	0.00e+00	947.00
IUUC-Opr-070248	Ochotona princeps	82.61	0.00e+00	799.00
IUUC-Ont-072083	Oreochromis niloticus	32.79	4.00e-71	261.00
IUUC-Oan-073364	Ornithorhynchus anatinus	71.66	9.00e-100	355.00
IUUC-Ocu-074572	Oryctolagus cuniculus	93.90	0.00e+00	966.00
IUUC-Oga-088378	Otolemur garnettii	89.66	0.00e+00	905.00
IUUC-Oar-089516	Ovis aries	88.12	0.00e+00	886.00
IUUC-Pan-092877	Papio anubis	99.80	0.00e+00	1021.00
IUUC-Psi-093928	Pelodiscus sinensis	59.58	6.00e-164	570.00
IUUC-Pfo-096690	Poecilia formosa	34.95	2.00e-69	256.00
IUUC-Pab-098624	Pongo abelii	99.59	0.00e+00	1013.00
IUUC-Pca-100469	Procavia capensis	83.51	0.00e+00	838.00
IUUC-Pva-103227	Pteropus vampyrus	90.67	0.00e+00	934.00
IUUC-Rno-105778	Rattus norvegicus	79.22	0.00e+00	806.00
IUUC-Sha-107392	Sarcophilus harrisii	69.82	0.00e+00	690.00
IUUC-Sar-113297	Sorex araneus	72.09	3.00e-53	201.00
IUUC-Ssc-115739	Sus scrofa	89.81	0.00e+00	902.00
IUUC-Tru-117718	Takifugu rubripes	32.21	8.00e-64	237.00
IUUC-Tbe-127926	Tupaia belangeri	86.43	5.00e-138	484.00
IUUC-Ttr-129293	Tursiops truncatus	90.87	0.00e+00	927.00
IUUC-Vpa-130379	Vicugna pacos	91.28	2.00e-159	554.00
IUUC-Xma-134222	Xiphophorus maculatus	33.12	2.00e-62	233.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence