iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-061994

Ensembl Protein ID

ENSMODP00000006511.1

UniProt Accession

F7E6W2; F7E6W2_MONDO

Protein Name

Ubiquitin-fold modifier-conjugating enzyme 1

Gene Name

UFC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000005282.1	ENSMODT00000006646.1	ENSMODP00000006511.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E2/Other	95.73	2.00e-91	331.00	IUUC-Hsa-046948

Active Site

Position(s)	Description	Evidence
116	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR008716-1}

Organism

Monodelphis domestica

Functional Description
(View)

E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.

Protein Sequence
(Fasta)

MADEATRRVV SEIPVLKTNA GPRDRELWVQ RLKEEYQALI RYVENNKKAD NDWFRLESNK 60
EGTRWFGKCW YIQDLLKYEF DLEFDIPITY PSTAPEIAVP ELDGKTAKMY RGGKICLTEH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGACG AAGCCACTCG ACGTGTTGTA TCGGAGATCC CGGTTCTGAA AACGAACGCC 60
GGGCCCCGGG ATCGCGAGCT ATGGGTTCAA AGGCTCAAGG AGGAGTATCA GGCTCTTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR016135--UBQ-conjugating_enzyme/RWD
IPR014806--Ufc1

Pfam

PF08694--UFC1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0071568--F:UFM1 transferase activity
GO:1990592--P:protein K69-linked ufmylation
GO:0034976--P:response to endoplasmic reticulum stress

KEGG

mdo:100032739

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000219	Aegilops tauschii	67.90	5.00e-31	125.00
IUUC-Aml-001773	Ailuropoda melanoleuca	93.90	1.00e-91	328.00
IUUC-Atr-002519	Amborella trichopoda	67.08	7.00e-68	249.00
IUUC-Aca-004597	Anolis carolinensis	87.80	4.00e-86	309.00
IUUC-Aly-005549	Arabidopsis lyrata	65.06	2.00e-65	241.00
IUUC-Ath-007416	Arabidopsis thaliana	65.06	2.00e-65	241.00
IUUC-Ame-011281	Astyanax mexicanus	87.43	3.00e-87	313.00
IUUC-Bta-012940	Bos taurus	95.73	8.00e-93	332.00
IUUC-Bdi-014987	Brachypodium distachyon	62.80	5.00e-62	229.00
IUUC-Bol-016532	Brassica oleracea	63.86	2.00e-65	240.00
IUUC-Bra-017971	Brassica rapa	63.86	2.00e-65	241.00
IUUC-Cel-018620	Caenorhabditis elegans	72.50	3.00e-71	259.00
IUUC-Cja-019762	Callithrix jacchus	95.73	1.00e-92	331.00
IUUC-Cfa-021172	Canis familiaris	95.12	1.00e-92	331.00
IUUC-Cpo-021575	Cavia porcellus	95.73	9.00e-93	331.00
IUUC-Cre-022894	Chlamydomonas reinhardtii	60.62	6.00e-60	222.00
IUUC-Csa-024240	Chlorocebus sabaeus	91.46	3.00e-88	317.00
IUUC-Cho-024457	Choloepus hoffmanni	92.98	3.00e-27	114.00
IUUC-Cin-025708	Ciona intestinalis	74.55	4.00e-76	276.00
IUUC-Csv-026307	Ciona savignyi	76.36	3.00e-77	280.00
IUUC-Dre-027752	Danio rerio	86.14	2.00e-87	314.00
IUUC-Dno-028957	Dasypus novemcinctus	93.71	2.00e-79	287.00
IUUC-Dor-030637	Dipodomys ordii	95.12	3.00e-92	330.00
IUUC-Dme-032033	Drosophila melanogaster	78.66	7.00e-80	288.00
IUUC-Ete-033056	Echinops telfairi	92.22	1.00e-90	324.00
IUUC-Eca-034260	Equus caballus	95.73	1.00e-92	331.00
IUUC-Eeu-034785	Erinaceus europaeus	58.18	3.00e-19	86.70
IUUC-Fca-035879	Felis catus	95.73	1.00e-92	331.00
IUUC-Gmo-039023	Gadus morhua	80.00	1.00e-83	301.00
IUUC-Gga-040475	Gallus gallus	82.64	3.00e-72	263.00
IUUC-Gac-041574	Gasterosteus aculeatus	78.79	4.00e-79	286.00
IUUC-Gma-043338	Glycine max	63.86	5.00e-66	243.00
IUUC-Ggo-044713	Gorilla gorilla	93.60	6.00e-69	252.00
IUUC-Hsa-046948	Homo sapiens	95.73	1.00e-92	331.00
IUUC-Hvu-047147	Hordeum vulgare	63.98	9.00e-62	229.00
IUUC-Itr-048742	Ictidomys tridecemlineatus	95.73	1.00e-92	331.00
IUUC-Lch-049654	Latimeria chalumnae	87.88	2.00e-88	317.00
IUUC-Lpe-051422	Leersia perrieri	63.98	5.00e-62	229.00
IUUC-Loc-051920	Lepisosteus oculatus	88.02	9.00e-90	322.00
IUUC-Laf-054338	Loxodonta africana	95.73	1.00e-92	331.00
IUUC-Mcc-054927	Macaca mulatta	95.73	1.00e-92	331.00
IUUC-Meu-056831	Macropus eugenii	96.95	4.00e-93	333.00
IUUC-Mtr-058091	Medicago truncatula	63.86	3.00e-65	240.00
IUUC-Mga-059933	Meleagris gallopavo	74.75	5.00e-44	168.00
IUUC-Mmr-061433	Microcebus murinus	95.12	1.00e-92	331.00
IUUC-Mmu-063398	Mus musculus	93.29	1.00e-91	327.00
IUUC-Mac-064536	Musa acuminata	61.45	1.00e-63	235.00
IUUC-Mpu-066795	Mustela putorius furo	95.73	8.00e-93	332.00
IUUC-Mlu-067983	Myotis lucifugus	93.98	2.00e-92	330.00
IUUC-Nle-069720	Nomascus leucogenys	95.50	1.00e-60	224.00
IUUC-Opr-070723	Ochotona princeps	95.73	8.00e-93	332.00
IUUC-Ont-071509	Oreochromis niloticus	81.93	7.00e-82	295.00
IUUC-Oan-073541	Ornithorhynchus anatinus	87.23	5.00e-22	95.10
IUUC-Ocu-074044	Oryctolagus cuniculus	95.73	8.00e-93	332.00
IUUC-Oba-075612	Oryza barthii	62.80	4.00e-62	230.00
IUUC-Obr-076432	Oryza brachyantha	62.80	3.00e-62	230.00
IUUC-Ogl-077071	Oryza glaberrima	62.80	4.00e-62	230.00
IUUC-Ogu-078427	Oryza glumaepatula	62.80	4.00e-62	230.00
IUUC-Oin-079963	Oryza indica	62.80	4.00e-62	230.00
IUUC-Olo-080455	Oryza longistaminata	62.80	4.00e-62	230.00
IUUC-Oni-082562	Oryza nivara	62.80	4.00e-62	230.00
IUUC-Opu-083688	Oryza punctata	63.35	1.00e-61	229.00
IUUC-Oru-084472	Oryza rufipogon	62.80	4.00e-62	230.00
IUUC-Osa-085623	Oryza sativa	62.80	4.00e-62	230.00
IUUC-Oga-088366	Otolemur garnettii	95.73	1.00e-92	331.00
IUUC-Oar-089754	Ovis aries	95.73	8.00e-93	332.00
IUUC-Ptr-090679	Pan troglodytes	95.12	2.00e-92	330.00
IUUC-Psi-093472	Pelodiscus sinensis	91.34	8.00e-69	251.00
IUUC-Ppa-095568	Physcomitrella patens	67.27	3.00e-68	250.00
IUUC-Pfo-097314	Poecilia formosa	80.49	1.00e-79	288.00
IUUC-Pab-098562	Pongo abelii	95.73	9.00e-93	332.00
IUUC-Pop-099506	Populus trichocarpa	65.43	2.00e-65	241.00
IUUC-Pca-101030	Procavia capensis	87.20	1.00e-81	295.00
IUUC-Ppe-101757	Prunus persica	63.86	1.00e-65	241.00
IUUC-Pva-102948	Pteropus vampyrus	96.34	4.00e-93	333.00
IUUC-Rno-105014	Rattus norvegicus	93.90	1.00e-91	328.00
IUUC-Sha-107297	Sarcophilus harrisii	97.55	5.00e-93	332.00
IUUC-Sit-110317	Setaria italica	62.96	2.00e-61	227.00
IUUC-Sly-111332	Solanum lycopersicum	64.46	3.00e-65	240.00
IUUC-Stu-112719	Solanum tuberosum	64.46	3.00e-65	240.00
IUUC-Sbi-114869	Sorghum bicolor	62.96	2.00e-61	228.00
IUUC-Ssc-116009	Sus scrofa	95.73	1.00e-92	331.00
IUUC-Tru-117527	Takifugu rubripes	81.21	3.00e-81	293.00
IUUC-Tsy-119195	Tarsius syrichta	91.49	5.00e-74	269.00
IUUC-Tni-120417	Tetraodon nigroviridis	81.21	5.00e-81	292.00
IUUC-Tca-120972	Theobroma cacao	65.06	5.00e-66	243.00
IUUC-Tae-124763	Triticum aestivum	63.98	2.00e-61	228.00
IUUC-Tur-126831	Triticum urartu	63.98	9.00e-62	229.00
IUUC-Tbe-128019	Tupaia belangeri	95.74	2.00e-79	286.00
IUUC-Ttr-129013	Tursiops truncatus	95.73	8.00e-93	332.00
IUUC-Vvi-131214	Vitis vinifera	63.86	1.00e-64	238.00
IUUC-Xtr-132182	Xenopus tropicalis	89.02	7.00e-88	315.00
IUUC-Xma-133877	Xiphophorus maculatus	80.49	2.00e-79	287.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence