iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071310

Ensembl Protein ID

ENSONIP00000013168.1

UniProt Accession

I3JWC3; I3JWC3_ORENI

Genbank Protein ID

ENSONIP00000013168

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01031540

Gene Name

usp32

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000010475.1	ENSONIT00000013178.1	ENSONIP00000013168.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.60e-107	359.3	733	1546

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++l+ k+  +ln++np ++ g+++k++ +l+ elw++++k+v+p +l  +++k+a++f+g
   Q: 733  TGLSNLGNTCFMNSSIQCVSNTKPLTDYFLSgKHLYELNRTNPIGMRGHMAKCYGDLVMELWSGTQKNVAPLKLRWTIAKYAPRFNG 819
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a+e++ ++n+s+++dlF+gqlksq+kc++c+++s r++p
   Q: 820  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaseAWENHLRRNRSIVVDLFHGQLKSQVKCKTCGHISARFDP 904
           ********************************9999..5555566777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++++++e                                                                      
   Q: 905  FNFLSLPLPMDSSMHLEitvikldgstpvryglrlnmdekytglkkqlselcslkpeqillaevhssniknfpqdnqkvrlsvngfl 991
           ************99999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 992  cafevpvpgsptslssptltditpianntaanghvgskldlipnggpcspetplangvanghitpvhespfigyiiamhrkmmrtel 1078
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1079 yflssqknrpslfgmplivpctvhtskkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvgkdgnlcawcpwyrf 1165
           *************************************************************************************** PP
   S: 186  ..........................................................slqdcLesftkeeelegenkyycekckkk 214
                                                                     sl++cL++ft+eeel +++ yyc+kck +
   Q: 1166 crgctiectedrasvgnayiavdwdptalhlryqtsqeriveehcsveqsrraqaepiSLDSCLKAFTSEEELGEDELYYCSKCKTH 1252
           *************************************************************************************** PP
   S: 215  qeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts................................. 267
           + a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f++                                  
   Q: 1253 RLATKKLDLWRLPPILIVHLKRFQFVNG--RWIKSQKIVKFPREnFDPSAFLAPrdlehrclhsrsesedllrvgednlssisapag 1337
           ***********************99775..5569********************888888888888888888888888888888888 PP
   S: 268  ................................................................peekqke................ 274
                                                                                 e                
   Q: 1338 fgnlpkaspassrksapslsrngspsgspktgsggrrpgrlrlpqlgsrhrlsnskenldgaanA-----Eaesrddvpqadpegsa 1419
           88887777777777777777777766666666666666666666666666666555555555550.....05555555555556666 PP
   S: 275  ..................................................................kkkYeLiavvvHsGslssGHY 295
                                                                             + +Y+L+a+ +HsG l++GHY
   Q: 1420 aggasglqgsgegvtsesssgseassshcdvvlvngdsnglcsdcstesstepdgsllqhrdnmclDAIYNLYAISCHSGILGGGHY 1506
           666666666666666666666677777777888888888888888888888899999999999999********************* PP
   S: 296  vayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           v+y+kn +gkW++++Ds+++ev+ ee+ +   ++aY+lfY+++
   Q: 1507 VTYAKNPNGKWYCYNDSSCKEVHSEEIDT---DSAYILFYEQQ 1546
           *****************************...********985 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MGAKESRIGF LSYDEAVKRV TDVELKRLKD AFKRTSGLSY YMTQQCFYRE VLGDGVPPKV 60
AEVIYTSFGG SAKGLHFNNL IVGLVLLTRG RDEEKAKYLF SLFASDLGGY AAREDIEAVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAAACATT CACCCGTTCA CCACATACAC ATACCGCCAG GAGCCCATTT CACAATAAAC 60
GGATAAGGCG ACAAACATCC CTGTCCAACT CAGCTCGTAA CGTTTATTTC CTCACACTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	73.77	0.00e+00	1999.00
IUUC-Apl-003272	Anas platyrhynchos	73.30	0.00e+00	2296.00
IUUC-Aca-005057	Anolis carolinensis	80.14	0.00e+00	2071.00
IUUC-Ame-010781	Astyanax mexicanus	79.63	0.00e+00	2546.00
IUUC-Bta-013502	Bos taurus	71.98	0.00e+00	2160.00
IUUC-Cja-018754	Callithrix jacchus	74.85	0.00e+00	2384.00
IUUC-Cfa-020526	Canis familiaris	74.80	0.00e+00	2353.00
IUUC-Cpo-021568	Cavia porcellus	71.26	0.00e+00	2120.00
IUUC-Csa-023143	Chlorocebus sabaeus	75.15	0.00e+00	2357.00
IUUC-Cho-024603	Choloepus hoffmanni	48.16	3.00e-143	503.00
IUUC-Cin-025583	Ciona intestinalis	49.96	0.00e+00	1260.00
IUUC-Csv-026344	Ciona savignyi	46.78	0.00e+00	1179.00
IUUC-Dre-028121	Danio rerio	80.95	0.00e+00	2535.00
IUUC-Dno-029911	Dasypus novemcinctus	74.26	0.00e+00	2298.00
IUUC-Dor-030608	Dipodomys ordii	57.83	5.00e-166	579.00
IUUC-Dme-032094	Drosophila melanogaster	45.26	6.00e-120	426.00
IUUC-Ete-032639	Echinops telfairi	83.98	0.00e+00	1108.00
IUUC-Eca-034253	Equus caballus	74.12	0.00e+00	2317.00
IUUC-Eeu-035084	Erinaceus europaeus	66.33	0.00e+00	1311.00
IUUC-Fca-035474	Felis catus	72.71	0.00e+00	1874.00
IUUC-Fal-036985	Ficedula albicollis	74.51	0.00e+00	2330.00
IUUC-Gmo-039568	Gadus morhua	90.38	0.00e+00	2399.00
IUUC-Gga-040509	Gallus gallus	74.91	0.00e+00	2414.00
IUUC-Gac-041757	Gasterosteus aculeatus	89.79	0.00e+00	2790.00
IUUC-Ggo-044956	Gorilla gorilla	76.18	0.00e+00	1528.00
IUUC-Hsa-046107	Homo sapiens	75.03	0.00e+00	2377.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	65.40	0.00e+00	801.00
IUUC-Lch-050681	Latimeria chalumnae	71.87	0.00e+00	2196.00
IUUC-Loc-052474	Lepisosteus oculatus	78.15	0.00e+00	2490.00
IUUC-Laf-054273	Loxodonta africana	74.50	0.00e+00	2362.00
IUUC-Mcc-054718	Macaca mulatta	74.78	0.00e+00	2366.00
IUUC-Meu-056558	Macropus eugenii	62.70	0.00e+00	1213.00
IUUC-Mga-059892	Meleagris gallopavo	75.08	0.00e+00	2312.00
IUUC-Mmr-060866	Microcebus murinus	74.54	0.00e+00	2398.00
IUUC-Mdo-062607	Monodelphis domestica	75.15	0.00e+00	2424.00
IUUC-Mmu-063797	Mus musculus	74.37	0.00e+00	2410.00
IUUC-Mpu-066121	Mustela putorius furo	75.46	0.00e+00	2399.00
IUUC-Mlu-067581	Myotis lucifugus	74.08	0.00e+00	2372.00
IUUC-Nle-069916	Nomascus leucogenys	72.81	0.00e+00	2251.00
IUUC-Opr-071073	Ochotona princeps	68.03	0.00e+00	947.00
IUUC-Oan-073356	Ornithorhynchus anatinus	74.41	0.00e+00	2372.00
IUUC-Ocu-074216	Oryctolagus cuniculus	74.74	0.00e+00	2367.00
IUUC-Ola-087434	Oryzias latipes	87.31	0.00e+00	2650.00
IUUC-Oga-089034	Otolemur garnettii	74.54	0.00e+00	2293.00
IUUC-Oar-090369	Ovis aries	75.35	0.00e+00	2348.00
IUUC-Ptr-090605	Pan troglodytes	74.78	0.00e+00	2365.00
IUUC-Pan-092381	Papio anubis	74.49	0.00e+00	2292.00
IUUC-Psi-093819	Pelodiscus sinensis	76.05	0.00e+00	2371.00
IUUC-Pma-094480	Petromyzon marinus	63.78	0.00e+00	1441.00
IUUC-Pfo-096561	Poecilia formosa	91.33	0.00e+00	2420.00
IUUC-Pab-097643	Pongo abelii	72.56	0.00e+00	2269.00
IUUC-Pca-100944	Procavia capensis	67.15	0.00e+00	818.00
IUUC-Pva-102732	Pteropus vampyrus	66.67	0.00e+00	2039.00
IUUC-Rno-105113	Rattus norvegicus	74.10	0.00e+00	2354.00
IUUC-Sar-113201	Sorex araneus	63.96	0.00e+00	1298.00
IUUC-Tgu-117322	Taeniopygia guttata	75.32	0.00e+00	2421.00
IUUC-Tru-118705	Takifugu rubripes	80.04	0.00e+00	700.00
IUUC-Tsy-119433	Tarsius syrichta	69.87	0.00e+00	1146.00
IUUC-Tni-120631	Tetraodon nigroviridis	85.07	0.00e+00	2623.00
IUUC-Tbe-127553	Tupaia belangeri	76.08	2.00e-170	593.00
IUUC-Ttr-128260	Tursiops truncatus	74.09	0.00e+00	2339.00
IUUC-Vpa-130479	Vicugna pacos	70.22	0.00e+00	2165.00
IUUC-Xtr-132686	Xenopus tropicalis	74.21	0.00e+00	2343.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence