iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089553

Ensembl Protein ID

ENSOARP00000006404.1

UniProt Accession

W5P7K0; W5P7K0_SHEEP

Genbank Protein ID

ENSOARP00000006404

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01013855

Gene Name

TRIM13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000005980.1	ENSOART00000006501.1	ENSOARP00000006404.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.80e-09	36.1	12	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H f+++Cl+ +    +  +   s  f+CP+Cr
   Q: 12   CPICCSLFDD-PRVLPCSHNFCKKCLEGIlegnVRNSLWRSSPFKCPTCR 60
           ********99.**************966667666666679999******8 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

DVMELLEEDL TCPICCSLFD DPRVLPCSHN FCKKCLEGIL EGNVRNSLWR SSPFKCPTCR 60
KETSATGVNS LQVNYSLKGI VEKYNKIKIS PKMPVCKGHL GQPLNIFCLT DMQLICGICA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGTGATGG AGCTGCTTGA AGAAGACCTC ACGTGCCCAA TCTGTTGCAG TCTGTTCGAT 60
GATCCCCGGG TTTTGCCTTG CTCACACAAC TTTTGCAAAA AGTGCTTAGA AGGGATCTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0097038--C:perinuclear endoplasmic reticulum
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010942--P:positive regulation of cell death
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016239--P:positive regulation of macroautophagy
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination
GO:0010332--P:response to gamma radiation
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002269	Ailuropoda melanoleuca	93.89	0.00e+00	737.00
IUUC-Apl-004168	Anas platyrhynchos	75.98	0.00e+00	630.00
IUUC-Aca-004395	Anolis carolinensis	69.85	1.00e-167	582.00
IUUC-Ame-011325	Astyanax mexicanus	46.75	2.00e-68	252.00
IUUC-Bta-012613	Bos taurus	99.02	0.00e+00	768.00
IUUC-Cja-018856	Callithrix jacchus	92.42	0.00e+00	787.00
IUUC-Cfa-021019	Canis familiaris	92.42	0.00e+00	728.00
IUUC-Cpo-021845	Cavia porcellus	91.89	0.00e+00	726.00
IUUC-Csa-023380	Chlorocebus sabaeus	91.89	0.00e+00	733.00
IUUC-Cho-024733	Choloepus hoffmanni	82.35	3.00e-89	322.00
IUUC-Dre-028675	Danio rerio	48.32	6.00e-110	390.00
IUUC-Dno-030018	Dasypus novemcinctus	91.18	0.00e+00	739.00
IUUC-Dor-030599	Dipodomys ordii	90.26	8.00e-131	459.00
IUUC-Ete-033134	Echinops telfairi	87.80	0.00e+00	726.00
IUUC-Eca-033931	Equus caballus	94.87	0.00e+00	735.00
IUUC-Eeu-034903	Erinaceus europaeus	91.44	0.00e+00	721.00
IUUC-Fca-035642	Felis catus	94.10	0.00e+00	729.00
IUUC-Fal-037108	Ficedula albicollis	76.72	0.00e+00	643.00
IUUC-Gga-040903	Gallus gallus	74.75	3.00e-180	624.00
IUUC-Ggo-044635	Gorilla gorilla	92.67	0.00e+00	741.00
IUUC-Hsa-046345	Homo sapiens	92.67	0.00e+00	741.00
IUUC-Itr-048220	Ictidomys tridecemlineatus	90.49	0.00e+00	704.00
IUUC-Lch-050599	Latimeria chalumnae	59.90	4.00e-138	484.00
IUUC-Loc-052378	Lepisosteus oculatus	63.73	9.00e-118	416.00
IUUC-Laf-053332	Loxodonta africana	91.42	0.00e+00	723.00
IUUC-Mcc-054705	Macaca mulatta	91.69	0.00e+00	735.00
IUUC-Meu-056825	Macropus eugenii	83.66	0.00e+00	711.00
IUUC-Mga-059528	Meleagris gallopavo	74.75	0.00e+00	634.00
IUUC-Mmr-060688	Microcebus murinus	93.40	0.00e+00	734.00
IUUC-Mdo-061882	Monodelphis domestica	82.40	0.00e+00	711.00
IUUC-Mmu-064352	Mus musculus	89.19	0.00e+00	741.00
IUUC-Mpu-066712	Mustela putorius furo	91.86	0.00e+00	678.00
IUUC-Mlu-068093	Myotis lucifugus	92.14	0.00e+00	714.00
IUUC-Nle-069310	Nomascus leucogenys	92.63	0.00e+00	734.00
IUUC-Ont-071759	Oreochromis niloticus	59.28	1.00e-110	393.00
IUUC-Oan-073673	Ornithorhynchus anatinus	80.73	0.00e+00	697.00
IUUC-Ocu-074192	Oryctolagus cuniculus	92.91	0.00e+00	741.00
IUUC-Ola-087424	Oryzias latipes	58.77	3.00e-109	388.00
IUUC-Oga-088808	Otolemur garnettii	92.63	0.00e+00	735.00
IUUC-Ptr-090518	Pan troglodytes	92.42	0.00e+00	738.00
IUUC-Pan-092781	Papio anubis	91.44	0.00e+00	733.00
IUUC-Psi-093914	Pelodiscus sinensis	75.06	0.00e+00	631.00
IUUC-Pfo-096346	Poecilia formosa	56.38	1.00e-110	392.00
IUUC-Pca-100914	Procavia capensis	89.51	0.00e+00	740.00
IUUC-Pva-102728	Pteropus vampyrus	93.40	0.00e+00	731.00
IUUC-Rno-105922	Rattus norvegicus	88.70	0.00e+00	686.00
IUUC-Sha-107124	Sarcophilus harrisii	83.62	0.00e+00	723.00
IUUC-Sja-107830	Schizosaccharomyces japonicus	37.21	3.00e-07	49.70
IUUC-Sar-113607	Sorex araneus	89.24	0.00e+00	702.00
IUUC-Ssc-116355	Sus scrofa	96.07	0.00e+00	748.00
IUUC-Tgu-116476	Taeniopygia guttata	76.47	0.00e+00	639.00
IUUC-Tru-118737	Takifugu rubripes	59.61	3.00e-112	398.00
IUUC-Tsy-118908	Tarsius syrichta	92.67	0.00e+00	753.00
IUUC-Tbe-127258	Tupaia belangeri	95.11	0.00e+00	746.00
IUUC-Vpa-130138	Vicugna pacos	94.62	0.00e+00	747.00
IUUC-Xtr-132100	Xenopus tropicalis	60.00	1.00e-136	479.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence