iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021646

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02007786

Gene Name

TRIM72

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000024725.1	ENSCPOT00000024691.1	ENSCPOP00000016814.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.80e-06	26.3	9	75
E3 activity/RING/RING	1.20e-08	35.3	14	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwl...asggk....tcPvtrqplteedlvPnltlrrli 65
           ++e+ Cp+ l+l+  Pv+l++G+++ r+++ +     a         cP +++p++++ l  n  l rl+
   Q: 9    YQELSCPLCLQLFDAPVTLECGHSFCRACLGRVGgepA---AdgtvPCPSCQAPTRPQVLSTNQQLARLV 75
           7899**************************99544442...155579*************9999987776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl+ f+  p++l CgH f++ Cl ++ g    + ++  CP C+
   Q: 14   CPLCLQLFDA-PVTLECGHSFCRACLGRV-GGEPAADGTVPCPSCQ 57
           ********99.******************.77779**********7 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MSAAPRLLYQ ELSCPLCLQL FDAPVTLECG HSFCRACLGR VGGEPAADGT VPCPSCQAPT 60
RPQVLSTNQQ LARLVEGLAQ VPQGHCEEHL DPLSIYCEQD RVLVCGVCAS LGSHRGHRLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGCTG CGCCCCGCCT CCTGTACCAG GAGCTGTCCT GCCCGCTGTG CCTGCAGCTG 60
TTCGATGCGC CTGTGACTCT CGAGTGTGGC CACAGTTTCT GCCGGGCCTG CCTGGGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0042383--C:sarcolemma
GO:0001786--F:phosphatidylserine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007517--P:muscle organ development
GO:0003012--P:muscle system process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0043569--P:negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010832--P:negative regulation of myotube differentiation
GO:0001778--P:plasma membrane repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002377	Ailuropoda melanoleuca	72.20	4.00e-179	620.00
IUUC-Aca-004755	Anolis carolinensis	62.23	8.00e-169	586.00
IUUC-Bta-013476	Bos taurus	73.52	0.00e+00	690.00
IUUC-Cja-018969	Callithrix jacchus	79.55	0.00e+00	711.00
IUUC-Cfa-020155	Canis familiaris	88.05	0.00e+00	823.00
IUUC-Cre-022560	Chlamydomonas reinhardtii	41.38	2.00e-06	47.80
IUUC-Csa-023855	Chlorocebus sabaeus	87.80	3.00e-166	577.00
IUUC-Dno-029142	Dasypus novemcinctus	87.00	0.00e+00	749.00
IUUC-Dor-030394	Dipodomys ordii	66.24	7.00e-82	297.00
IUUC-Ete-032801	Echinops telfairi	83.85	4.00e-63	234.00
IUUC-Eca-034378	Equus caballus	88.05	0.00e+00	807.00
IUUC-Eeu-034526	Erinaceus europaeus	82.84	0.00e+00	743.00
IUUC-Fca-036440	Felis catus	87.21	0.00e+00	828.00
IUUC-Ggo-045086	Gorilla gorilla	90.96	0.00e+00	654.00
IUUC-Hsa-046533	Homo sapiens	89.52	0.00e+00	810.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	89.10	0.00e+00	832.00
IUUC-Laf-054479	Loxodonta africana	88.03	0.00e+00	818.00
IUUC-Mcc-055814	Macaca mulatta	87.47	0.00e+00	776.00
IUUC-Meu-056767	Macropus eugenii	71.28	0.00e+00	666.00
IUUC-Mmr-061616	Microcebus murinus	88.89	0.00e+00	838.00
IUUC-Mdo-062252	Monodelphis domestica	74.16	0.00e+00	697.00
IUUC-Mmu-063094	Mus musculus	87.63	0.00e+00	808.00
IUUC-Mpu-065885	Mustela putorius furo	73.79	0.00e+00	626.00
IUUC-Mlu-068150	Myotis lucifugus	62.72	1.00e-81	296.00
IUUC-Nle-069476	Nomascus leucogenys	89.75	0.00e+00	808.00
IUUC-Opr-070871	Ochotona princeps	88.71	1.00e-137	483.00
IUUC-Oan-072738	Ornithorhynchus anatinus	75.68	0.00e+00	708.00
IUUC-Ocu-074132	Oryctolagus cuniculus	75.21	0.00e+00	640.00
IUUC-Oga-088268	Otolemur garnettii	62.13	8.00e-144	503.00
IUUC-Oar-089555	Ovis aries	68.37	7.00e-161	560.00
IUUC-Ptr-090792	Pan troglodytes	89.52	0.00e+00	810.00
IUUC-Pan-092897	Papio anubis	89.31	0.00e+00	809.00
IUUC-Pma-094519	Petromyzon marinus	26.43	3.00e-24	105.00
IUUC-Pab-098716	Pongo abelii	89.73	0.00e+00	809.00
IUUC-Pca-100618	Procavia capensis	80.17	0.00e+00	729.00
IUUC-Pva-102430	Pteropus vampyrus	78.41	0.00e+00	716.00
IUUC-Rno-105665	Rattus norvegicus	87.42	0.00e+00	828.00
IUUC-Sha-106854	Sarcophilus harrisii	60.77	2.00e-166	578.00
IUUC-Sar-113028	Sorex araneus	86.73	1.00e-140	492.00
IUUC-Ssc-116124	Sus scrofa	89.05	0.00e+00	809.00
IUUC-Tbe-127273	Tupaia belangeri	87.18	5.00e-119	421.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence