iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092158

Ensembl Protein ID

ENSPANP00000000144.1

UniProt Accession

A0A096MKV8; A0A096MKV8_PAPAN

Genbank Protein ID

ENSPANP00000000144

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01034992

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000007890.1	ENSPANT00000010045.1	ENSPANP00000000144.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.60e-08	33.9	12	53
UBD/SH3	8.30e-32	109.0	383	437

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+e ++   +vlpC+H+f++ Clq++     ++ ke rCP Cr
   Q: 12   CPVCFEKLDVTAKVLPCQHTFCKPCLQRV----FKAHKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + + +l++y+a   deL l+kG+ v+v+  ++qd gWl+gv+  +g+ G+fP+n+v 
   Q: 383  NMFVALHSYSAHGPDELDLQKGEGVRVL-GKCQD-GWLRGVSLVTGRVGIFPNNYVI 437
           7889************************.77776.9*******************96 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MDDLTLLDLL ECPVCFEKLD VTAKVLPCQH TFCKPCLQRV FKAHKELRCP ECRTPVFCSI 60
EALPANLLLV RLLDGVRSGQ SSGRGGSFRR PGMMTLQDGR KNRTNPRRLQ ASPFRLVPNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAAGAATTC TGACGTTCTC AAGAGGCCAG CTCTGCCCCC GTTGCTCAAC TGACCTTACC 60
ATGTGGACTC TGCTCCTCCA GGTGGGAACT GGAGTTTTGA AATAAAATGG ATGATTTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PF13445--zf-RING_UBOX

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	89.12	0.00e+00	827.00
IUUC-Apl-003443	Anas platyrhynchos	67.36	8.00e-154	537.00
IUUC-Aca-004632	Anolis carolinensis	59.12	1.00e-147	516.00
IUUC-Bta-013400	Bos taurus	90.52	0.00e+00	826.00
IUUC-Cel-018180	Caenorhabditis elegans	27.22	3.00e-22	100.00
IUUC-Cja-019686	Callithrix jacchus	95.53	0.00e+00	883.00
IUUC-Cfa-020893	Canis familiaris	91.51	0.00e+00	845.00
IUUC-Cpo-021638	Cavia porcellus	84.81	0.00e+00	807.00
IUUC-Csa-023846	Chlorocebus sabaeus	98.64	0.00e+00	935.00
IUUC-Cho-024609	Choloepus hoffmanni	86.84	9.00e-164	570.00
IUUC-Dno-028940	Dasypus novemcinctus	85.03	0.00e+00	787.00
IUUC-Dor-030491	Dipodomys ordii	89.50	6.00e-109	388.00
IUUC-Dse-031414	Dothistroma septosporum	31.94	2.00e-07	51.60
IUUC-Ete-032513	Echinops telfairi	86.32	0.00e+00	853.00
IUUC-Eca-034241	Equus caballus	91.10	0.00e+00	856.00
IUUC-Eeu-034636	Erinaceus europaeus	85.32	0.00e+00	728.00
IUUC-Fca-035862	Felis catus	90.69	0.00e+00	814.00
IUUC-Gga-040748	Gallus gallus	58.92	3.00e-124	439.00
IUUC-Ggo-045267	Gorilla gorilla	95.91	0.00e+00	912.00
IUUC-Hsa-045761	Homo sapiens	95.91	0.00e+00	909.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	87.43	0.00e+00	845.00
IUUC-Lch-050498	Latimeria chalumnae	55.06	5.00e-115	408.00
IUUC-Laf-054061	Loxodonta africana	77.45	2.00e-165	575.00
IUUC-Mcc-054746	Macaca mulatta	99.23	0.00e+00	935.00
IUUC-Meu-056390	Macropus eugenii	81.20	1.00e-47	184.00
IUUC-Mga-059398	Meleagris gallopavo	65.15	7.00e-90	323.00
IUUC-Mmr-061390	Microcebus murinus	91.21	0.00e+00	669.00
IUUC-Mdo-062951	Monodelphis domestica	78.97	0.00e+00	789.00
IUUC-Mmu-063840	Mus musculus	81.77	0.00e+00	768.00
IUUC-Mpu-065840	Mustela putorius furo	89.38	0.00e+00	843.00
IUUC-Mlu-067378	Myotis lucifugus	86.62	0.00e+00	784.00
IUUC-Ncr-068956	Neurospora crassa	33.33	1.00e-07	52.40
IUUC-Nle-069535	Nomascus leucogenys	95.91	0.00e+00	858.00
IUUC-Opr-070739	Ochotona princeps	85.11	0.00e+00	794.00
IUUC-Oan-073468	Ornithorhynchus anatinus	72.82	0.00e+00	646.00
IUUC-Ocu-074343	Oryctolagus cuniculus	86.78	0.00e+00	808.00
IUUC-Oga-088276	Otolemur garnettii	80.74	0.00e+00	749.00
IUUC-Oar-090315	Ovis aries	88.70	0.00e+00	812.00
IUUC-Ptr-091119	Pan troglodytes	95.72	0.00e+00	910.00
IUUC-Psi-092959	Pelodiscus sinensis	63.26	0.00e+00	627.00
IUUC-Pab-097675	Pongo abelii	96.50	0.00e+00	897.00
IUUC-Pca-101021	Procavia capensis	77.46	0.00e+00	690.00
IUUC-Pva-102619	Pteropus vampyrus	90.31	0.00e+00	822.00
IUUC-Rno-105918	Rattus norvegicus	82.34	0.00e+00	783.00
IUUC-Sha-107391	Sarcophilus harrisii	71.81	0.00e+00	733.00
IUUC-Sja-107661	Schizosaccharomyces japonicus	44.83	3.00e-10	59.30
IUUC-Sar-113148	Sorex araneus	81.84	0.00e+00	640.00
IUUC-Tgu-116584	Taeniopygia guttata	56.97	7.00e-110	390.00
IUUC-Tsy-118968	Tarsius syrichta	75.10	0.00e+00	639.00
IUUC-Tbe-128007	Tupaia belangeri	90.61	0.00e+00	815.00
IUUC-Ttr-128499	Tursiops truncatus	87.62	0.00e+00	819.00
IUUC-Vpa-130075	Vicugna pacos	95.90	3.00e-70	259.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence