iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ang-009818

Ensembl Protein ID

CAK97316

UniProt Accession

A2R5J1; MYO1_ASPNC

Genbank Protein ID

CAK97316.1

Protein Name

Myosin-1; Class I unconventional myosin; Type I myosin

Genbank Nucleotide ID

AM270343

Gene Name

myoA; An15g04490

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
An15g04490	CAK97316	CAK97316

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-10	40.8	1096	1150

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
             +vlyd+++ +++eL++++Gd v+++   ++ +gW+ + ++++  +G  Pe + e+
   Q: 1096 MAKVLYDFNSDQSNELSIRAGDLVQIV--SKEGNGWWLCMNTTTSVQGWTPEAYLEE 1150
           579************************..67788******************99875 PP

Organism

Aspergillus niger

Functional Description
(View)

Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity).

Protein Sequence
(Fasta)

MGHSRRPAGG EKKSRGFGRS KAAADVGDGR QAGKPQVKKA VFESTKKKEI GVSDLTLLSK 60
ISNEAINDNL KLRFEHDEIY TYIGHVLVSV NPFRDLGIYT DRVLESYRGK NRLEVPPHVF 120

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Nucleotide Sequence
(Fasta)

ATGGTGAGTC GCGGCCCATT TCACTGCCAG TTCGATGACA GAGGTTTATA CTTTTGTAAT 60
AAATTATCTT CTACTAACCC CATGTCTCGT TGTAGGGTCA TTCACGACGT CCGGCTGGCG 120

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Sequence Source

Ensembl

Keyword

KW-0009--Actin-binding
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0378--Hydrolase
KW-0505--Motor protein
KW-0518--Myosin
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain

Interpro

IPR001609--Myosin_head_motor_dom
IPR010926--Myosin_TH1
IPR027417--P-loop_NTPase
IPR001452--SH3_domain

PROSITE

PS51456--MYOSIN_MOTOR
PS50002--SH3
PS51757--TH1

Pfam

PF00063--Myosin_head
PF06017--Myosin_TH1
PF00018--SH3_1

PRINTS

PR00193--MYOSINHEAVY

SMART

SM00242--MYSc
SM00326--SH3

Gene Ontology

GO:0030479--C:actin cortical patch
GO:0016459--C:myosin complex
GO:0005524--F:ATP binding
GO:0003774--F:motor activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002158	Ailuropoda melanoleuca	43.72	0.00e+00	761.00
IUUC-Apl-003803	Anas platyrhynchos	43.82	0.00e+00	763.00
IUUC-Aca-004926	Anolis carolinensis	42.08	0.00e+00	709.00
IUUC-Acl-008168	Aspergillus clavatus	92.40	0.00e+00	1907.00
IUUC-Afl-008552	Aspergillus flavus	92.95	0.00e+00	1913.00
IUUC-Afu-008958	Aspergillus fumigatus	88.68	3.00e-25	109.00
IUUC-Aor-009891	Aspergillus oryzae	92.86	0.00e+00	1910.00
IUUC-Ate-010325	Aspergillus terreus	92.60	0.00e+00	1905.00
IUUC-Ame-011036	Astyanax mexicanus	43.69	0.00e+00	771.00
IUUC-Bta-012409	Bos taurus	43.18	0.00e+00	775.00
IUUC-Cel-018582	Caenorhabditis elegans	42.47	0.00e+00	709.00
IUUC-Cfa-020409	Canis familiaris	43.03	0.00e+00	765.00
IUUC-Cpo-021332	Cavia porcellus	43.49	0.00e+00	778.00
IUUC-Csa-023357	Chlorocebus sabaeus	43.73	0.00e+00	736.00
IUUC-Dre-027800	Danio rerio	45.53	0.00e+00	767.00
IUUC-Dno-029858	Dasypus novemcinctus	43.51	0.00e+00	733.00
IUUC-Dor-030253	Dipodomys ordii	42.32	1.00e-170	592.00
IUUC-Dse-031169	Dothistroma septosporum	43.40	9.00e-09	55.50
IUUC-Eca-034303	Equus caballus	42.64	0.00e+00	701.00
IUUC-Eeu-034561	Erinaceus europaeus	38.57	4.00e-50	191.00
IUUC-Fca-036174	Felis catus	40.87	0.00e+00	680.00
IUUC-Fal-037393	Ficedula albicollis	44.11	0.00e+00	764.00
IUUC-Gmo-038566	Gadus morhua	41.16	0.00e+00	665.00
IUUC-Gga-040323	Gallus gallus	45.04	0.00e+00	773.00
IUUC-Gac-042415	Gasterosteus aculeatus	43.34	0.00e+00	717.00
IUUC-Hsa-045712	Homo sapiens	43.72	0.00e+00	774.00
IUUC-Itr-048108	Ictidomys tridecemlineatus	42.55	0.00e+00	749.00
IUUC-Lch-050042	Latimeria chalumnae	43.04	0.00e+00	718.00
IUUC-Loc-052303	Lepisosteus oculatus	43.77	0.00e+00	771.00
IUUC-Laf-054148	Loxodonta africana	43.40	0.00e+00	732.00
IUUC-Mcc-054773	Macaca mulatta	43.79	0.00e+00	778.00
IUUC-Meu-056504	Macropus eugenii	39.37	1.00e-82	300.00
IUUC-Mmr-061357	Microcebus murinus	43.72	0.00e+00	776.00
IUUC-Mdo-062467	Monodelphis domestica	43.54	0.00e+00	766.00
IUUC-Mmu-063711	Mus musculus	43.59	0.00e+00	775.00
IUUC-Mpu-066658	Mustela putorius furo	43.99	0.00e+00	779.00
IUUC-Nfi-068411	Neosartorya fischeri	92.41	0.00e+00	1865.00
IUUC-Ont-072236	Oreochromis niloticus	43.17	0.00e+00	761.00
IUUC-Oan-073284	Ornithorhynchus anatinus	29.44	2.00e-22	98.60
IUUC-Ocu-074538	Oryctolagus cuniculus	43.20	0.00e+00	765.00
IUUC-Oga-088985	Otolemur garnettii	44.38	0.00e+00	767.00
IUUC-Oar-089527	Ovis aries	43.84	0.00e+00	715.00
IUUC-Pan-092029	Papio anubis	43.79	0.00e+00	778.00
IUUC-Psi-094016	Pelodiscus sinensis	33.19	2.00e-137	481.00
IUUC-Pma-094458	Petromyzon marinus	44.49	0.00e+00	754.00
IUUC-Pfo-096486	Poecilia formosa	44.22	0.00e+00	726.00
IUUC-Pca-100128	Procavia capensis	33.40	1.00e-68	253.00
IUUC-Rno-105992	Rattus norvegicus	43.27	0.00e+00	775.00
IUUC-Sha-107424	Sarcophilus harrisii	43.25	0.00e+00	759.00
IUUC-Ssc-115400	Sus scrofa	43.93	0.00e+00	780.00
IUUC-Tgu-116572	Taeniopygia guttata	43.42	0.00e+00	689.00
IUUC-Tru-118665	Takifugu rubripes	43.43	0.00e+00	753.00
IUUC-Tre-122048	Trichoderma reesei	57.14	7.00e-15	75.10
IUUC-Tbe-127462	Tupaia belangeri	34.38	3.00e-105	374.00
IUUC-Ttr-128783	Tursiops truncatus	43.84	0.00e+00	726.00
IUUC-Vda-130020	Verticillium dahliae	71.41	0.00e+00	1408.00
IUUC-Xtr-131936	Xenopus tropicalis	42.37	0.00e+00	740.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence