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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063898
UUCD1 version UUC-MuM-01058
Ensembl Protein ID ENSMUSP00000025631.6
UniProt Accession Q62422; Q3UF05; OSTF1_MOUSE
Genbank Protein ID AAC52641.1; BAB22442.1; BAB24098.1; BAB25477.1; BAB25685.1; BAB26683.1; BAE26777.1; BAE28756.1; BAE29340.1; BAE33000.1; AAH60986.1
Protein Name Osteoclast-stimulating factor 1; SH3 domain protein 3
Genbank Nucleotide ID U58888; AK002899; AK005525; AK008123; AK008467; AK010074; AK145949; AK149175; AK150145; AK155028; BC060986
Gene Name Ostf1; Sh3d3; Sh3p2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000024725.12 ENSMUST00000025631.6 ENSMUSP00000025631.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMPhospho.ELM
UniProtPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 3.50e-14 53.6 14 68
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            +++++ly +e+ + deL +++Gd++++   +  d  W+kg  + +g+ Gl+P+n+v++
   Q: 14   VKVFRALYTFEPRTPDELYFEEGDIIYIT--DMSDTSWWKG--TCKGRTGLIPSNYVAE 68
           57899***********************7..99********..8*************86 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
 Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
Protein Sequence
(Fasta)
MSKPPPKPVK PGQVKVFRAL YTFEPRTPDE LYFEEGDIIY ITDMSDTSWW KGTCKGRTGL 60
IPSNYVAEQA ESIDNPLHEA AKRGNLSWLR ECLDNRVGVN GLDKAGSTAL YWACHGGHKD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063898|UBD,SH3|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGAGCTCGCT GGTCCGAGTG TCCCGCATCG GGTTGCGCGC GGATCCGGAG CGGCCGCGGC 60
CAGCGCAGGC TTGGCGCCCA GTTCTCGTGT GCGTGTGGGG CTCCCGCGGC TGAGCCTGGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063898|UBD,SH3|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001452--SH3_domain
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50002--SH3
Pfam

PF12796--Ank_2
PF00018--SH3_1
PRINTS

PR01415--ANKYRIN
PR00452--SH3DOMAIN
SMART

SM00248--ANK
SM00326--SH3
Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0017124--F:SH3 domain binding
KEGG mmu:20409
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001728 Ailuropoda melanoleuca 94.47 1.00e-110 392.00
IUUC-Apl-003751 Anas platyrhynchos 88.04 2.00e-104 371.00
IUUC-Aca-004876 Anolis carolinensis 92.09 3.00e-110 390.00
IUUC-Bta-012630 Bos taurus 95.48 4.00e-112 397.00
IUUC-Cel-018470 Caenorhabditis elegans 51.76 9.00e-50 189.00
IUUC-Cja-019917 Callithrix jacchus 96.48 2.00e-112 397.00
IUUC-Cfa-020190 Canis familiaris 97.25 1.00e-104 372.00
IUUC-Cpo-021650 Cavia porcellus 93.47 8.00e-109 385.00
IUUC-Csa-023311 Chlorocebus sabaeus 95.98 5.00e-112 396.00
IUUC-Cho-025043 Choloepus hoffmanni 86.21 5.00e-101 360.00
IUUC-Cin-025298 Ciona intestinalis 55.88 1.00e-53 202.00
IUUC-Csv-025890 Ciona savignyi 56.16 1.00e-60 225.00
IUUC-Dre-028036 Danio rerio 81.78 1.00e-99 355.00
IUUC-Dno-029567 Dasypus novemcinctus 95.98 5.00e-112 396.00
IUUC-Dor-031060 Dipodomys ordii 96.48 2.00e-112 398.00
IUUC-Eca-034406 Equus caballus 95.59 3.00e-114 404.00
IUUC-Fca-036234 Felis catus 96.05 9.00e-101 358.00
IUUC-Fal-037466 Ficedula albicollis 91.20 2.00e-109 387.00
IUUC-Gmo-039340 Gadus morhua 79.53 3.00e-99 354.00
IUUC-Gga-041127 Gallus gallus 92.59 1.00e-110 392.00
IUUC-Gac-042291 Gasterosteus aculeatus 80.00 5.00e-99 353.00
IUUC-Ggo-045142 Gorilla gorilla 95.48 5.00e-111 393.00
IUUC-Hsa-045670 Homo sapiens 95.48 5.00e-111 393.00
IUUC-Lch-050433 Latimeria chalumnae 85.58 4.00e-104 370.00
IUUC-Loc-052660 Lepisosteus oculatus 84.19 1.00e-103 368.00
IUUC-Laf-053692 Loxodonta africana 95.63 2.00e-114 404.00
IUUC-Mcc-054763 Macaca mulatta 95.98 5.00e-112 396.00
IUUC-Mga-059479 Meleagris gallopavo 95.05 7.00e-103 366.00
IUUC-Mmr-061426 Microcebus murinus 94.97 7.00e-111 392.00
IUUC-Mdo-062513 Monodelphis domestica 93.97 1.00e-110 392.00
IUUC-Mpu-066606 Mustela putorius furo 97.04 8.00e-97 345.00
IUUC-Mlu-068187 Myotis lucifugus 93.69 6.00e-112 396.00
IUUC-Nle-069167 Nomascus leucogenys 95.98 5.00e-112 396.00
IUUC-Opr-070908 Ochotona princeps 95.57 1.00e-113 401.00
IUUC-Ont-072428 Oreochromis niloticus 82.79 1.00e-102 365.00
IUUC-Oan-072823 Ornithorhynchus anatinus 94.17 5.00e-113 399.00
IUUC-Ocu-074375 Oryctolagus cuniculus 96.98 4.00e-113 400.00
IUUC-Ola-086922 Oryzias latipes 82.33 2.00e-101 361.00
IUUC-Oga-088253 Otolemur garnettii 94.97 1.00e-110 391.00
IUUC-Oar-090217 Ovis aries 96.10 1.00e-114 405.00
IUUC-Ptr-091605 Pan troglodytes 95.48 5.00e-111 393.00
IUUC-Pan-092701 Papio anubis 95.98 5.00e-112 396.00
IUUC-Psi-093852 Pelodiscus sinensis 93.95 9.00e-114 402.00
IUUC-Pfo-096294 Poecilia formosa 80.93 7.00e-101 359.00
IUUC-Pva-102840 Pteropus vampyrus 74.88 2.00e-82 298.00
IUUC-Rno-105149 Rattus norvegicus 98.99 9.00e-115 405.00
IUUC-Sha-106884 Sarcophilus harrisii 93.20 7.00e-112 395.00
IUUC-Sja-107861 Schizosaccharomyces japonicus 36.63 8.00e-11 59.30
IUUC-Ssc-115549 Sus scrofa 95.98 6.00e-112 396.00
IUUC-Tgu-116709 Taeniopygia guttata 91.20 2.00e-109 387.00
IUUC-Tru-118367 Takifugu rubripes 84.65 1.00e-104 372.00
IUUC-Tni-120613 Tetraodon nigroviridis 82.79 1.00e-101 362.00
IUUC-Tbe-128089 Tupaia belangeri 79.46 3.00e-80 290.00
IUUC-Vpa-130041 Vicugna pacos 73.89 4.00e-78 283.00
IUUC-Xtr-132694 Xenopus tropicalis 83.74 3.00e-100 357.00
Created Date 25-Jun-2017

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