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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063268
UUCD1 version UUC-MuM-00338
Ensembl Protein ID ENSMUSP00000118070.1
UniProt Accession P63032; Q9WVD3; RHES_MOUSE
Genbank Protein ID BAB30023.1; AAH26377.1
Protein Name GTP-binding protein Rhes; Ras homolog enriched in striatum
Genbank Nucleotide ID AK015898; BC026377
Gene Name Rasd2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000034472.13 ENSMUST00000139848.7 ENSMUSP00000118070.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/Other 95.11 9.00e-151 530.00 IUUC-Hsa-046937
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.
 GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.
Protein Sequence
(Fasta)
MMKTLSSGNC TLNVPAKNSY RMVVLGASRV GKSSIVSRFL NGRFEDQYTP TIEDFHRKVY 60
NIHGDMYQLD ILDTSGNHPF PAMRRLSILT GDVFILVFSL DSRESFDEVK RLQKQILEVK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063268|E3,E3 activity/Other|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGTACGCAG TGACCCTGGA GCCCCCGCAG ACGCCGGGAG ACTCAGCGGT CGGAGCGGCA 60
GGCGGCTCCC CGCACCTCCA GGAGCTTCCA GGGAGCCCTC CAAGCCGTGC TCGGGGTCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063268|E3,E3 activity/Other|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0085--Behavior
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0488--Methylation
KW-0547--Nucleotide-binding
KW-0636--Prenylation
KW-1185--Reference proteome
Interpro

IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR001806--Small_GTPase
IPR020849--Small_GTPase_Ras
PROSITE

PS51421--RAS
Pfam

PF00071--Ras
Gene Ontology

GO:0005622--C:intracellular
GO:0005886--C:plasma membrane
GO:0031681--F:G-protein beta-subunit binding
GO:0005525--F:GTP binding
GO:0007626--P:locomotory behavior
GO:0031397--P:negative regulation of protein ubiquitination
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0033235--P:positive regulation of protein sumoylation
GO:0043949--P:regulation of cAMP-mediated signaling
GO:0007264--P:small GTPase mediated signal transduction
GO:0001963--P:synaptic transmission, dopaminergic
KEGG mmu:75141
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002300 Ailuropoda melanoleuca 95.11 7.00e-152 529.00
IUUC-Apl-003857 Anas platyrhynchos 87.59 1.00e-140 491.00
IUUC-Aca-004240 Anolis carolinensis 87.97 3.00e-140 490.00
IUUC-Bta-013228 Bos taurus 93.98 7.00e-150 522.00
IUUC-Cja-018957 Callithrix jacchus 94.74 2.00e-151 527.00
IUUC-Cfa-020131 Canis familiaris 95.11 3.00e-152 530.00
IUUC-Cpo-021614 Cavia porcellus 91.73 8.00e-147 512.00
IUUC-Csa-023844 Chlorocebus sabaeus 95.11 4.00e-152 530.00
IUUC-Dno-029174 Dasypus novemcinctus 96.24 3.00e-153 533.00
IUUC-Dor-031033 Dipodomys ordii 94.36 5.00e-151 526.00
IUUC-Dme-031780 Drosophila melanogaster 47.23 3.00e-62 232.00
IUUC-Ete-032309 Echinops telfairi 93.14 1.00e-95 341.00
IUUC-Eca-034018 Equus caballus 94.74 2.00e-151 527.00
IUUC-Fca-035875 Felis catus 94.74 2.00e-151 528.00
IUUC-Fal-037653 Ficedula albicollis 86.47 2.00e-138 484.00
IUUC-Gga-040943 Gallus gallus 87.97 1.00e-140 492.00
IUUC-Ggo-044688 Gorilla gorilla 95.11 5.00e-152 530.00
IUUC-Hsa-046937 Homo sapiens 95.11 4.00e-152 530.00
IUUC-Itr-048300 Ictidomys tridecemlineatus 95.86 2.00e-153 534.00
IUUC-Lch-050232 Latimeria chalumnae 79.28 2.00e-119 421.00
IUUC-Laf-053676 Loxodonta africana 94.74 2.00e-151 528.00
IUUC-Meu-056249 Macropus eugenii 91.35 4.00e-146 510.00
IUUC-Mga-059257 Meleagris gallopavo 87.97 6.00e-141 493.00
IUUC-Mdo-061991 Monodelphis domestica 91.35 1.00e-145 508.00
IUUC-Mpu-066901 Mustela putorius furo 95.49 1.00e-152 531.00
IUUC-Mlu-067258 Myotis lucifugus 95.11 4.00e-152 530.00
IUUC-Nle-068973 Nomascus leucogenys 95.11 6.00e-152 530.00
IUUC-Opr-070743 Ochotona princeps 94.36 3.00e-150 524.00
IUUC-Oan-072868 Ornithorhynchus anatinus 89.89 1.00e-142 498.00
IUUC-Ocu-074790 Oryctolagus cuniculus 94.36 8.00e-151 525.00
IUUC-Oga-088431 Otolemur garnettii 95.49 9.00e-153 532.00
IUUC-Oar-089258 Ovis aries 95.17 4.00e-116 410.00
IUUC-Ptr-090978 Pan troglodytes 95.11 4.00e-152 530.00
IUUC-Pan-092088 Papio anubis 93.28 6.00e-132 462.00
IUUC-Psi-093630 Pelodiscus sinensis 87.97 7.00e-141 492.00
IUUC-Pma-094385 Petromyzon marinus 35.94 4.00e-26 111.00
IUUC-Pab-098310 Pongo abelii 95.11 4.00e-152 530.00
IUUC-Pca-100098 Procavia capensis 92.48 4.00e-145 506.00
IUUC-Pva-102212 Pteropus vampyrus 93.61 4.00e-150 523.00
IUUC-Rno-105257 Rattus norvegicus 100.00 3.00e-160 556.00
IUUC-Sha-106504 Sarcophilus harrisii 91.35 3.00e-146 510.00
IUUC-Sar-113244 Sorex araneus 91.48 3.00e-93 333.00
IUUC-Tgu-116948 Taeniopygia guttata 86.09 6.00e-138 483.00
IUUC-Tur-126269 Triticum urartu 32.69 1.90e+00 26.20
IUUC-Tbe-127818 Tupaia belangeri 95.11 3.00e-152 530.00
IUUC-Ttr-128286 Tursiops truncatus 93.98 9.00e-150 522.00
Created Date 25-Jun-2017

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