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Tag Content
UUCD2 ID IUUC-Nle-069886
UUCD1 version UUC-NoL-00127
Ensembl Protein ID ENSNLEP00000003103.1
UniProt Accession G1QQ85; G1QQ85_NOMLE
Genbank Protein ID ENSNLEP00000003103
Protein Name Uncharacterized protein
Genbank Nucleotide ID ADFV01177482
Gene Name ZNRF3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSNLEG00000002538.2 ENSNLET00000003260.2 ENSNLEP00000003103.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 9.30e-06 26.1 193 234
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCle +   ++++v pC H fh++C+  w        ++ +CP Cr
   Q: 193  CAICLEKYidGEELRVIPCTHRFHRKCVDPW------LLQHHTCPHCR 234
           ********66334******************......9999******8 PP
   
Organism Nomascus leucogenys
Protein Sequence
(Fasta)
MHPLGLCNNN DEEDLYEYGW VGVVKLEQPE LDPKPCLTVL GKAKRAVQRG ATAVIFDVSE 60
NPEAIDQLNQ GSEDPLKRPV VYVKGADAIK LMNIVNKQKV ARARIQHRPP RQPTEYFDMG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Nle-069886|E3,RING|Nomascus leucogenys
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGATGCACCC ACTGGGCCTA TGTAATAACA ATGACGAAGA GGACTTGTAT GAATATGGCT 60
GGGTAGGAGT GGTGAAGCTG GAACAGCCAG AATTGGACCC GAAACCATGC CTCACTGTCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Nle-069886|E3,RING|Nomascus leucogenys
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF13639--zf-RING_2
SMART

SM00184--RING
Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
KEGG nle:100594544
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001916 Ailuropoda melanoleuca 86.42 0.00e+00 1220.00
IUUC-Apl-004188 Anas platyrhynchos 71.02 0.00e+00 1032.00
IUUC-Aca-004606 Anolis carolinensis 36.51 8.00e-26 111.00
IUUC-Aly-005850 Arabidopsis lyrata 42.68 5.00e-15 73.60
IUUC-Ath-007372 Arabidopsis thaliana 42.68 2.00e-14 71.60
IUUC-Ame-011764 Astyanax mexicanus 61.60 0.00e+00 717.00
IUUC-Bta-012478 Bos taurus 65.72 0.00e+00 639.00
IUUC-Bol-016217 Brassica oleracea 56.25 3.00e-14 70.90
IUUC-Bra-017407 Brassica rapa 56.25 3.00e-14 70.90
IUUC-Cja-019504 Callithrix jacchus 95.27 0.00e+00 1433.00
IUUC-Cfa-020048 Canis familiaris 88.97 0.00e+00 1314.00
IUUC-Cpo-021725 Cavia porcellus 81.07 0.00e+00 1186.00
IUUC-Csa-023586 Chlorocebus sabaeus 96.63 0.00e+00 1399.00
IUUC-Cho-024867 Choloepus hoffmanni 92.70 0.00e+00 691.00
IUUC-Cin-025569 Ciona intestinalis 47.11 1.00e-55 210.00
IUUC-Csv-025869 Ciona savignyi 45.04 5.00e-49 189.00
IUUC-Dre-027553 Danio rerio 64.13 0.00e+00 783.00
IUUC-Dno-029370 Dasypus novemcinctus 84.48 0.00e+00 1196.00
IUUC-Dor-030816 Dipodomys ordii 80.76 0.00e+00 1120.00
IUUC-Ete-033060 Echinops telfairi 74.49 0.00e+00 832.00
IUUC-Eca-034044 Equus caballus 87.86 0.00e+00 1305.00
IUUC-Eeu-034591 Erinaceus europaeus 66.06 2.00e-134 473.00
IUUC-Fca-036000 Felis catus 87.97 0.00e+00 1310.00
IUUC-Fal-037147 Ficedula albicollis 70.74 0.00e+00 1033.00
IUUC-Gmo-039099 Gadus morhua 49.57 8.00e-116 410.00
IUUC-Gga-041243 Gallus gallus 67.88 0.00e+00 816.00
IUUC-Gac-041340 Gasterosteus aculeatus 48.71 1.00e-110 393.00
IUUC-Gma-044387 Glycine max 41.98 5.00e-15 73.90
IUUC-Ggo-044953 Gorilla gorilla 97.82 0.00e+00 1431.00
IUUC-Hsa-046484 Homo sapiens 98.42 0.00e+00 1448.00
IUUC-Itr-048470 Ictidomys tridecemlineatus 88.26 0.00e+00 1288.00
IUUC-Lch-050004 Latimeria chalumnae 58.16 0.00e+00 655.00
IUUC-Loc-051830 Lepisosteus oculatus 62.01 0.00e+00 764.00
IUUC-Laf-053975 Loxodonta africana 85.71 0.00e+00 1253.00
IUUC-Mcc-055302 Macaca mulatta 95.91 0.00e+00 1362.00
IUUC-Meu-056263 Macropus eugenii 74.45 0.00e+00 783.00
IUUC-Mtr-058744 Medicago truncatula 54.17 2.00e-13 68.60
IUUC-Mga-059706 Meleagris gallopavo 71.46 0.00e+00 1051.00
IUUC-Mmr-061372 Microcebus murinus 90.79 0.00e+00 1234.00
IUUC-Mdo-062651 Monodelphis domestica 64.90 0.00e+00 856.00
IUUC-Mmu-064339 Mus musculus 83.80 0.00e+00 1243.00
IUUC-Mac-065356 Musa acuminata 50.00 1.00e-12 67.80
IUUC-Mpu-066211 Mustela putorius furo 86.52 0.00e+00 1253.00
IUUC-Mlu-067058 Myotis lucifugus 88.15 0.00e+00 1226.00
IUUC-Opr-070218 Ochotona princeps 81.77 0.00e+00 1092.00
IUUC-Ont-072483 Oreochromis niloticus 60.41 0.00e+00 756.00
IUUC-Oan-073718 Ornithorhynchus anatinus 70.76 0.00e+00 910.00
IUUC-Ocu-073847 Oryctolagus cuniculus 80.77 0.00e+00 1053.00
IUUC-Opu-083306 Oryza punctata 67.44 7.00e-13 67.00
IUUC-Ola-087358 Oryzias latipes 61.38 0.00e+00 752.00
IUUC-Oga-088362 Otolemur garnettii 88.00 0.00e+00 1314.00
IUUC-Oar-090197 Ovis aries 99.49 1.00e-96 347.00
IUUC-Ptr-091350 Pan troglodytes 98.30 0.00e+00 1445.00
IUUC-Pan-091700 Papio anubis 95.91 0.00e+00 1357.00
IUUC-Psi-093301 Pelodiscus sinensis 68.90 0.00e+00 971.00
IUUC-Pfo-096917 Poecilia formosa 62.40 0.00e+00 749.00
IUUC-Pab-097932 Pongo abelii 97.58 0.00e+00 1454.00
IUUC-Pop-099640 Populus trichocarpa 57.14 1.00e-14 72.80
IUUC-Pca-101054 Procavia capensis 92.87 0.00e+00 953.00
IUUC-Pva-102879 Pteropus vampyrus 89.35 0.00e+00 1321.00
IUUC-Pgr-103476 Puccinia graminis 41.27 3.00e-09 55.50
IUUC-Sha-106507 Sarcophilus harrisii 53.42 2.00e-160 559.00
IUUC-Sit-110656 Setaria italica 67.44 6.00e-13 67.00
IUUC-Stu-112500 Solanum tuberosum 62.79 8.00e-13 66.60
IUUC-Sar-113182 Sorex araneus 81.98 2.00e-111 396.00
IUUC-Sbi-114414 Sorghum bicolor 41.03 8.00e-13 65.90
IUUC-Ssc-115966 Sus scrofa 81.01 0.00e+00 1058.00
IUUC-Tgu-116864 Taeniopygia guttata 62.70 0.00e+00 667.00
IUUC-Tru-118502 Takifugu rubripes 60.85 0.00e+00 726.00
IUUC-Tsy-119210 Tarsius syrichta 89.78 0.00e+00 1273.00
IUUC-Tni-120344 Tetraodon nigroviridis 51.88 2.00e-119 422.00
IUUC-Tca-120966 Theobroma cacao 48.39 4.00e-13 68.90
IUUC-Tbe-127735 Tupaia belangeri 85.93 3.00e-132 465.00
IUUC-Ttr-128714 Tursiops truncatus 75.87 0.00e+00 979.00
IUUC-Xtr-132280 Xenopus tropicalis 57.56 0.00e+00 687.00
Created Date 25-Jun-2017

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