iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090160

Ensembl Protein ID

ENSOARP00000010918.1

UniProt Accession

W5PKE7; W5PKE7_SHEEP

Genbank Protein ID

ENSOARP00000010918

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01089307

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010179.1	ENSOART00000011076.1	ENSOARP00000010918.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-09	38.2	711	755

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gge    l++CekC ++fH  C+ ++   ++p+ e wiC+ Cr
   Q: 711  DWCAVCQNGGE----LLCCEKCPKVFHLSCHVPT-LANFPSGE-WICTFCR 755
           79*********....*******************.*******8.******8 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MRLLTVGVIR CPVCSQECAE RHIIDNFFVK DTTEVPSSTV EKSNQVCTSC EDNAEANGFC 60
VECVEWLCKT CIRAHQRVKF TKDHTVRQKE EVSPEAVGVT SQRPVFCPFH KKEQLKLYCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCCCCACC CCCCAGCCTC CTCCTCCGGG CTGCGTGGCC CGTGCAACCC GTACTTCTGA 60
AAACCTCTGT TGGAGTGCGC TGTTGTCTAT CTCCAGCCCT TTGCCGGCTG CATCTAGTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	97.84	0.00e+00	1588.00
IUUC-Apl-003697	Anas platyrhynchos	79.62	0.00e+00	1286.00
IUUC-Bta-013282	Bos taurus	99.14	0.00e+00	1625.00
IUUC-Cja-018920	Callithrix jacchus	96.23	0.00e+00	1602.00
IUUC-Cfa-020984	Canis familiaris	97.95	0.00e+00	1602.00
IUUC-Cpo-022035	Cavia porcellus	95.37	0.00e+00	1597.00
IUUC-Csa-024208	Chlorocebus sabaeus	96.99	0.00e+00	1605.00
IUUC-Cho-024413	Choloepus hoffmanni	65.18	4.00e-162	565.00
IUUC-Dno-029145	Dasypus novemcinctus	96.99	0.00e+00	1620.00
IUUC-Dor-030396	Dipodomys ordii	93.92	0.00e+00	1217.00
IUUC-Ete-032414	Echinops telfairi	87.30	0.00e+00	909.00
IUUC-Eca-033489	Equus caballus	98.06	0.00e+00	1598.00
IUUC-Eeu-034654	Erinaceus europaeus	94.49	0.00e+00	764.00
IUUC-Fca-035844	Felis catus	93.88	0.00e+00	1471.00
IUUC-Fal-036735	Ficedula albicollis	80.49	0.00e+00	1305.00
IUUC-Gga-041124	Gallus gallus	80.81	0.00e+00	1280.00
IUUC-Ggo-044542	Gorilla gorilla	97.09	0.00e+00	1603.00
IUUC-Hsa-046785	Homo sapiens	96.99	0.00e+00	1602.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	96.77	0.00e+00	1587.00
IUUC-Laf-054279	Loxodonta africana	94.19	0.00e+00	1553.00
IUUC-Mcc-055668	Macaca mulatta	97.09	0.00e+00	1607.00
IUUC-Meu-056195	Macropus eugenii	77.78	0.00e+00	800.00
IUUC-Mga-059272	Meleagris gallopavo	80.81	0.00e+00	1281.00
IUUC-Mmr-060936	Microcebus murinus	96.02	0.00e+00	1587.00
IUUC-Mdo-062848	Monodelphis domestica	90.15	0.00e+00	1476.00
IUUC-Mmu-063598	Mus musculus	94.62	0.00e+00	1549.00
IUUC-Mpu-066272	Mustela putorius furo	97.31	0.00e+00	1583.00
IUUC-Mlu-067958	Myotis lucifugus	95.17	0.00e+00	1583.00
IUUC-Nle-069375	Nomascus leucogenys	97.09	0.00e+00	1607.00
IUUC-Opr-070836	Ochotona princeps	81.86	0.00e+00	656.00
IUUC-Oan-073393	Ornithorhynchus anatinus	80.39	0.00e+00	1003.00
IUUC-Ocu-074873	Oryctolagus cuniculus	95.07	0.00e+00	1561.00
IUUC-Oga-088692	Otolemur garnettii	95.80	0.00e+00	1560.00
IUUC-Ptr-090756	Pan troglodytes	96.99	0.00e+00	1602.00
IUUC-Pan-091719	Papio anubis	96.88	0.00e+00	1601.00
IUUC-Psi-093433	Pelodiscus sinensis	80.81	0.00e+00	1334.00
IUUC-Pab-098599	Pongo abelii	95.59	0.00e+00	1575.00
IUUC-Pca-100540	Procavia capensis	87.96	0.00e+00	961.00
IUUC-Pva-102478	Pteropus vampyrus	90.20	0.00e+00	1414.00
IUUC-Rno-105478	Rattus norvegicus	77.82	0.00e+00	652.00
IUUC-Sha-106740	Sarcophilus harrisii	85.49	0.00e+00	1377.00
IUUC-Sar-113615	Sorex araneus	95.35	0.00e+00	1400.00
IUUC-Ssc-115513	Sus scrofa	97.32	1.00e-147	515.00
IUUC-Tgu-117368	Taeniopygia guttata	79.19	0.00e+00	1305.00
IUUC-Tsy-118904	Tarsius syrichta	96.55	0.00e+00	1601.00
IUUC-Tbe-127354	Tupaia belangeri	84.44	0.00e+00	710.00
IUUC-Ttr-128983	Tursiops truncatus	93.80	0.00e+00	1201.00
IUUC-Vpa-130420	Vicugna pacos	95.80	0.00e+00	1564.00
IUUC-Vvi-131561	Vitis vinifera	49.06	1.00e-12	68.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence