iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093433

Ensembl Protein ID

ENSPSIP00000017710.1

UniProt Accession

K7GBP9; K7GBP9_PELSI

Genbank Protein ID

ENSPSIP00000017710

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01195555

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000015663.1	ENSPSIT00000017789.1	ENSPSIP00000017710.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.20e-09	37.4	706	750

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gge    l++CekC ++fH  C+ +s   ++p+ e wiC+ Cr
   Q: 706  DWCAVCQNGGE----LLCCEKCPKVFHLSCHVPS-LMNFPRGE-WICTFCR 750
           79*********....*******************.*******8.******8 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MYLTWMFGVI RCPICSQECA ERHIIDNFFV KDTTEVPSST VEKSNQVCTS CEDNAEANGF 60
CVECVEWLCK TCIRAHQRVK FTKDHTVRQK EEVSPEAVGV NSQRPVFCPF HKKEQLKLYC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNGGC GGGTAGGTGG GAGGGGAGAA ATCCTGAAAG 60
GGAGCCCGGC CCCTCTGTTG TGTGTGCTGG GCAGCCAACT TCCAGGAGCA AATGCGGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	81.85	0.00e+00	1349.00
IUUC-Apl-003697	Anas platyrhynchos	86.78	0.00e+00	1418.00
IUUC-Bta-013282	Bos taurus	81.05	0.00e+00	1338.00
IUUC-Cja-018920	Callithrix jacchus	81.85	0.00e+00	1366.00
IUUC-Cfa-020984	Canis familiaris	81.85	0.00e+00	1346.00
IUUC-Cpo-022035	Cavia porcellus	81.63	0.00e+00	1379.00
IUUC-Csa-024208	Chlorocebus sabaeus	82.17	0.00e+00	1371.00
IUUC-Dno-029145	Dasypus novemcinctus	81.73	0.00e+00	1395.00
IUUC-Dor-030396	Dipodomys ordii	77.89	0.00e+00	1021.00
IUUC-Dme-032143	Drosophila melanogaster	28.83	2.00e-37	151.00
IUUC-Ete-032414	Echinops telfairi	76.90	0.00e+00	788.00
IUUC-Eca-033489	Equus caballus	82.06	0.00e+00	1362.00
IUUC-Eeu-034654	Erinaceus europaeus	74.95	2.00e-174	605.00
IUUC-Fca-035844	Felis catus	79.23	0.00e+00	1244.00
IUUC-Fal-036735	Ficedula albicollis	85.13	0.00e+00	1433.00
IUUC-Gga-041124	Gallus gallus	85.05	0.00e+00	1392.00
IUUC-Ggo-044542	Gorilla gorilla	82.28	0.00e+00	1372.00
IUUC-Hsa-046785	Homo sapiens	82.17	0.00e+00	1370.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	82.06	0.00e+00	1355.00
IUUC-Laf-054279	Loxodonta africana	80.94	0.00e+00	1360.00
IUUC-Mcc-055668	Macaca mulatta	82.28	0.00e+00	1372.00
IUUC-Meu-056195	Macropus eugenii	70.87	0.00e+00	736.00
IUUC-Mga-059272	Meleagris gallopavo	85.70	0.00e+00	1397.00
IUUC-Mmr-060936	Microcebus murinus	81.53	0.00e+00	1350.00
IUUC-Mdo-062848	Monodelphis domestica	82.44	0.00e+00	1367.00
IUUC-Mmu-063598	Mus musculus	81.44	0.00e+00	1330.00
IUUC-Mpu-066272	Mustela putorius furo	81.74	0.00e+00	1337.00
IUUC-Mlu-067958	Myotis lucifugus	80.81	0.00e+00	1362.00
IUUC-Nle-069375	Nomascus leucogenys	82.28	0.00e+00	1372.00
IUUC-Oan-073393	Ornithorhynchus anatinus	78.58	0.00e+00	933.00
IUUC-Ocu-074873	Oryctolagus cuniculus	80.77	0.00e+00	1354.00
IUUC-Oga-088692	Otolemur garnettii	81.63	0.00e+00	1322.00
IUUC-Oar-090160	Ovis aries	81.31	0.00e+00	1344.00
IUUC-Ptr-090756	Pan troglodytes	82.17	0.00e+00	1370.00
IUUC-Pan-091719	Papio anubis	82.17	0.00e+00	1370.00
IUUC-Pma-094506	Petromyzon marinus	61.36	1.00e-49	187.00
IUUC-Pab-098599	Pongo abelii	80.88	0.00e+00	1342.00
IUUC-Pca-100540	Procavia capensis	78.04	0.00e+00	839.00
IUUC-Pva-102478	Pteropus vampyrus	76.37	0.00e+00	1204.00
IUUC-Sha-106740	Sarcophilus harrisii	78.11	0.00e+00	1290.00
IUUC-Sar-113615	Sorex araneus	79.79	0.00e+00	1157.00
IUUC-Tgu-117368	Taeniopygia guttata	84.18	0.00e+00	1405.00
IUUC-Tsy-118904	Tarsius syrichta	82.06	0.00e+00	1365.00
IUUC-Tbe-127354	Tupaia belangeri	67.77	2.00e-168	585.00
IUUC-Ttr-128983	Tursiops truncatus	76.10	0.00e+00	979.00
IUUC-Vpa-130420	Vicugna pacos	79.70	0.00e+00	1317.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence