iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132279

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

TNF receptor-associated factor 2

Genbank Nucleotide ID

AAMC01128578

Gene Name

traf2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000003950.3	ENSXETT00000008559.3	ENSXETP00000008559.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	60.60	9.00e-174	607.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

AAAVSGSPQG SLDLNQPGFK KEILGTKLEV KYLCSDCKNL LRRPLQAQCG HRYCSHCLNK 60
IISTGPQKCS ACIQEGIIGG GSLVMSGTSL LPTNRNLHSV NPLYVGYCFT AAGNCREFPK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGCCGCAG TGTCCGGCTC TCCGCAGGGA TCTCTGGACC TGAACCAACC GGGGTTTAAG 60
AAGGAGATTC TGGGCACCAA GCTCGAGGTG AAGTACCTGT GTTCCGACTG CAAGAATTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0051865--P:protein autoubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0046328--P:regulation of JNK cascade
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	57.47	2.00e-174	605.00
IUUC-Apl-004202	Anas platyrhynchos	61.28	0.00e+00	659.00
IUUC-Aca-005029	Anolis carolinensis	47.54	3.00e-111	394.00
IUUC-Ame-011841	Astyanax mexicanus	71.55	9.00e-103	367.00
IUUC-Bta-013180	Bos taurus	57.23	1.00e-169	589.00
IUUC-Cja-019813	Callithrix jacchus	60.00	1.00e-177	616.00
IUUC-Cfa-021205	Canis familiaris	60.60	2.00e-174	604.00
IUUC-Cpo-021346	Cavia porcellus	59.60	4.00e-176	610.00
IUUC-Csa-023809	Chlorocebus sabaeus	59.05	1.00e-151	529.00
IUUC-Dre-027669	Danio rerio	51.98	7.00e-149	520.00
IUUC-Dno-029458	Dasypus novemcinctus	56.89	8.00e-171	593.00
IUUC-Dor-030338	Dipodomys ordii	57.60	8.00e-157	546.00
IUUC-Eca-034401	Equus caballus	60.71	2.00e-180	625.00
IUUC-Eeu-034668	Erinaceus europaeus	69.08	2.00e-61	229.00
IUUC-Fca-036057	Felis catus	58.24	2.00e-178	618.00
IUUC-Fal-037560	Ficedula albicollis	59.81	1.00e-170	592.00
IUUC-Gmo-038964	Gadus morhua	53.95	2.00e-157	548.00
IUUC-Gga-040425	Gallus gallus	62.36	0.00e+00	664.00
IUUC-Gac-041908	Gasterosteus aculeatus	57.94	8.00e-167	580.00
IUUC-Ggo-044606	Gorilla gorilla	53.28	3.00e-152	531.00
IUUC-Hsa-046952	Homo sapiens	60.60	1.00e-179	622.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	52.90	4.00e-144	504.00
IUUC-Lch-049571	Latimeria chalumnae	49.40	8.00e-149	520.00
IUUC-Loc-051973	Lepisosteus oculatus	54.33	1.00e-150	526.00
IUUC-Laf-053815	Loxodonta africana	58.28	1.00e-170	592.00
IUUC-Mcc-054888	Macaca mulatta	60.48	1.00e-177	616.00
IUUC-Meu-056547	Macropus eugenii	53.42	2.00e-127	449.00
IUUC-Mga-059819	Meleagris gallopavo	61.92	6.00e-180	623.00
IUUC-Mdo-062570	Monodelphis domestica	63.47	0.00e+00	641.00
IUUC-Mmu-063133	Mus musculus	57.60	8.00e-166	576.00
IUUC-Mpu-065802	Mustela putorius furo	58.01	5.00e-175	607.00
IUUC-Nle-070155	Nomascus leucogenys	60.40	1.00e-179	622.00
IUUC-Opr-070856	Ochotona princeps	57.52	8.00e-73	267.00
IUUC-Ont-071930	Oreochromis niloticus	56.72	5.00e-169	587.00
IUUC-Ola-087397	Oryzias latipes	53.54	9.00e-165	573.00
IUUC-Oga-088109	Otolemur garnettii	60.00	3.00e-178	617.00
IUUC-Oar-090310	Ovis aries	75.82	4.00e-85	308.00
IUUC-Ptr-090643	Pan troglodytes	60.60	4.00e-180	624.00
IUUC-Pan-091933	Papio anubis	60.48	2.00e-177	614.00
IUUC-Psi-093681	Pelodiscus sinensis	60.12	2.00e-178	618.00
IUUC-Pfo-096148	Poecilia formosa	53.92	3.00e-165	575.00
IUUC-Pab-098631	Pongo abelii	60.40	1.00e-179	622.00
IUUC-Pca-100582	Procavia capensis	50.21	4.00e-60	225.00
IUUC-Pva-102396	Pteropus vampyrus	51.00	1.00e-140	492.00
IUUC-Rno-106120	Rattus norvegicus	55.82	3.00e-163	567.00
IUUC-Sha-106493	Sarcophilus harrisii	63.27	0.00e+00	650.00
IUUC-Sar-113570	Sorex araneus	77.90	3.00e-86	311.00
IUUC-Ssc-115843	Sus scrofa	57.23	8.00e-175	606.00
IUUC-Tgu-117144	Taeniopygia guttata	59.09	2.00e-162	565.00
IUUC-Tru-117853	Takifugu rubripes	54.49	1.00e-163	569.00
IUUC-Tni-120256	Tetraodon nigroviridis	57.60	1.00e-169	588.00
IUUC-Tbe-127943	Tupaia belangeri	52.03	3.00e-75	274.00
IUUC-Ttr-129246	Tursiops truncatus	59.24	7.00e-173	600.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence