iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020415

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03012839

Gene Name

TRIM21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000006025.3	ENSCAFT00000009720.3	ENSCAFP00000009023.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.40e-06	26.7	12	73
E3 activity/RING/RING	1.70e-07	31.9	16	55

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrli 65
           ee  CpI l++  +P+ + +G+++  ++I +  ++gg  cPv+++++  ++l Pn  l +++
   Q: 12   EEVTCPICLDPVVEPMSIDCGHSFCHKCISEVGKDGGGVCPVCQHTFLLRNLRPNWPLANVV 73
           6889***************************9999999*****************8776665 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++  + p++ +CgH f+++C+  +      + +   CP+C+
   Q: 16   CPICLDPVVE-PMSIDCGHSFCHKCISEV-----GKDGGGVCPVCQ 55
           ********99.***************999.....7889999****7 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAAAMPLAMM WEEVTCPICL DPVVEPMSID CGHSFCHKCI SEVGKDGGGV CPVCQHTFLL 60
RNLRPNWPLA NVVDNLKQIG QNANEVTQRE WCQVHGERLH LFCEEDGKIL CWVCSQSQNH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGACACGCC TCGACGGGAA ATCGAAAGTG AAATAGGGAG CCTGCCGCCG GCTGCCGAAA 60
GCCCTGAAAA GGTGAGTGAC TCGCCCCGAC CCGAGTGCCC CCGCCCTGGC TGGGGGACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR020457--Znf_B-box_chordata
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01406--BBOXZNFINGER
PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0090086--P:negative regulation of protein deubiquitination
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010508--P:positive regulation of autophagy
GO:0045787--P:positive regulation of cell cycle
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0046598--P:positive regulation of viral entry into host cell
GO:0051865--P:protein autoubiquitination
GO:0031648--P:protein destabilization
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0070206--P:protein trimerization
GO:0034341--P:response to interferon-gamma

KEGG

cfa:485226

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001896	Ailuropoda melanoleuca	86.90	0.00e+00	833.00
IUUC-Ang-009772	Aspergillus niger	41.43	1.00e-08	52.80
IUUC-Ate-010384	Aspergillus terreus	40.38	2.00e-07	48.90
IUUC-Bta-013083	Bos taurus	69.39	0.00e+00	630.00
IUUC-Cja-019002	Callithrix jacchus	75.60	0.00e+00	703.00
IUUC-Cpo-021948	Cavia porcellus	68.12	0.00e+00	637.00
IUUC-Csa-023135	Chlorocebus sabaeus	76.91	0.00e+00	654.00
IUUC-Cho-024493	Choloepus hoffmanni	63.37	3.00e-88	318.00
IUUC-Dno-030061	Dasypus novemcinctus	69.18	0.00e+00	657.00
IUUC-Ete-033168	Echinops telfairi	67.34	2.00e-159	555.00
IUUC-Eca-033578	Equus caballus	77.24	0.00e+00	725.00
IUUC-Eeu-034749	Erinaceus europaeus	54.31	9.00e-123	433.00
IUUC-Fca-035468	Felis catus	81.04	0.00e+00	764.00
IUUC-Ggo-045190	Gorilla gorilla	76.03	0.00e+00	679.00
IUUC-Hsa-046583	Homo sapiens	76.03	0.00e+00	676.00
IUUC-Itr-048632	Ictidomys tridecemlineatus	71.30	0.00e+00	641.00
IUUC-Laf-053455	Loxodonta africana	72.71	0.00e+00	644.00
IUUC-Mcc-054609	Macaca mulatta	76.69	0.00e+00	650.00
IUUC-Mmr-061369	Microcebus murinus	69.54	2.00e-165	575.00
IUUC-Mmu-063166	Mus musculus	67.18	2.00e-176	611.00
IUUC-Mpu-066889	Mustela putorius furo	83.41	0.00e+00	801.00
IUUC-Mlu-067647	Myotis lucifugus	78.34	0.00e+00	679.00
IUUC-Nle-069567	Nomascus leucogenys	75.38	0.00e+00	669.00
IUUC-Opr-071178	Ochotona princeps	64.92	1.00e-166	578.00
IUUC-Oar-090413	Ovis aries	73.41	0.00e+00	654.00
IUUC-Ptr-091187	Pan troglodytes	76.03	0.00e+00	676.00
IUUC-Pan-092231	Papio anubis	76.64	0.00e+00	649.00
IUUC-Pab-098079	Pongo abelii	72.19	8.00e-132	463.00
IUUC-Pca-100639	Procavia capensis	69.05	4.00e-134	471.00
IUUC-Pva-102476	Pteropus vampyrus	76.42	0.00e+00	709.00
IUUC-Rno-105054	Rattus norvegicus	67.40	3.00e-157	548.00
IUUC-Sar-113204	Sorex araneus	72.08	0.00e+00	630.00
IUUC-Ssc-116291	Sus scrofa	73.80	0.00e+00	678.00
IUUC-Tsy-118803	Tarsius syrichta	72.89	3.00e-129	455.00
IUUC-Tbe-127337	Tupaia belangeri	58.38	1.00e-99	356.00
IUUC-Ttr-128914	Tursiops truncatus	72.27	1.00e-175	609.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence