iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116256

Ensembl Protein ID

ENSSSCP00000030229.1

UniProt Accession

A5D9M6; A5D9M5; A5D9M7; B9TSQ3; BAG6_PIG

Genbank Protein ID

ABX82810.1; CAN59675.1; CAN59676.1; CAN59677.1

Protein Name

Large proline-rich protein BAG6; BCL2-associated athanogene 6; HLA-B-associated transcript 3

Genbank Nucleotide ID

EU282341; BX548169; BX548169; BX548169

Gene Name

BAG6; BAT3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000001410.3	ENSSSCT00000034959.1	ENSSSCP00000029976.1
ENSSSCG00000001410.3	ENSSSCT00000034083.1	ENSSSCP00000030229.1
ENSSSCG00000001410.3	ENSSSCT00000034548.1	ENSSSCP00000029165.1
ENSSSCG00000001410.3	ENSSSCT00000034386.1	ENSSSCP00000029889.1
ENSSSCG00000001410.3	ENSSSCT00000036064.1	ENSSSCP00000028825.1
ENSSSCG00000001410.3	ENSSSCT00000035973.1	ENSSSCP00000029172.1
ENSSSCG00000001410.3	ENSSSCT00000035395.1	ENSSSCP00000029728.1
ENSSSCG00000001410.3	ENSSSCT00000032967.1	ENSSSCP00000030611.1
ENSSSCG00000001410.3	ENSSSCT00000001543.2	ENSSSCP00000001501.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_PIM	5.30e-20	71.4	18	90

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_PIM

   S: 2    kltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           ++ vktl++++ ++ v  +++v+e+Ke+ia++ ++p e+q+LIy+G++L+Dd++L+e+++  g+v+hlv + ++
   Q: 18   EVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYNVG-GKVIHLVERAPP 90
           799*********************************************************9.*******99876 PP

Organism

Sus scrofa

Functional Description
(View)

May mediate ricin-induced apoptosis.

Protein Sequence
(Fasta)

MEPNDSTSTT MEEPESLEVL VKTLDSQTRT FIVGAQMNVK EFKEHIAASV SIPSEKQRLI 60
YQGRVLQDDK KLQEYNVGGK VIHLVERAPP QTQLPSGASS GTGSASATHG GGPPPGTRGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGGAGGCG TCCTTTTTTA TAAACAAACG TCCTGAAAGG TAGTAAATCC TCAACTTTTC 60
CAAAACATGA TAATGTCCCC CCGCGGCCGC ACACCGCGGG AAGGAACATG GCGCCCACGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0053--Apoptosis
KW-0143--Chaperone
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0221--Differentiation
KW-0391--Immunity
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0964--Secreted
KW-0744--Spermatogenesis
KW-0813--Transport

Interpro

IPR021925--DUF3538
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2

Pfam

PF12057--DUF3538
PF00240--ubiquitin

SMART

SM00213--UBQ

Gene Ontology

GO:0071818--C:BAT3 complex
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0031593--F:polyubiquitin binding
GO:0070628--F:proteasome binding
GO:0043022--F:ribosome binding
GO:0015643--F:toxic substance binding
GO:0007420--P:brain development
GO:0030154--P:cell differentiation
GO:0016569--P:covalent chromatin modification
GO:0009790--P:embryo development
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0002429--P:immune response-activating cell surface receptor signaling pathway
GO:0018393--P:internal peptidyl-lysine acetylation
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0001822--P:kidney development
GO:0030324--P:lung development
GO:1904378--P:maintenance of unfolded protein involved in ERAD pathway
GO:0030101--P:natural killer cell activation
GO:0043066--P:negative regulation of apoptotic process
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045861--P:negative regulation of proteolysis
GO:1904294--P:positive regulation of ERAD pathway
GO:0050821--P:protein stabilization
GO:0042981--P:regulation of apoptotic process
GO:0007283--P:spermatogenesis
GO:0007130--P:synaptonemal complex assembly
GO:0071816--P:tail-anchored membrane protein insertion into ER membrane
GO:0006810--P:transport
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ssc:100153950

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000364	Aegilops tauschii	44.74	2.00e-12	68.20
IUUC-Aml-001312	Ailuropoda melanoleuca	92.25	0.00e+00	1448.00
IUUC-Atr-002741	Amborella trichopoda	37.78	5.00e-19	90.10
IUUC-Aca-005226	Anolis carolinensis	68.88	2.00e-157	550.00
IUUC-Aly-005932	Arabidopsis lyrata	41.61	2.00e-17	84.30
IUUC-Ath-006845	Arabidopsis thaliana	40.88	1.00e-15	78.60
IUUC-Acl-008361	Aspergillus clavatus	36.78	4.00e-09	55.80
IUUC-Afl-008403	Aspergillus flavus	36.78	2.00e-09	56.60
IUUC-Afu-009029	Aspergillus fumigatus	34.48	1.00e-08	54.30
IUUC-Ang-009826	Aspergillus niger	37.65	2.00e-10	59.30
IUUC-Aor-010091	Aspergillus oryzae	36.78	2.00e-09	56.60
IUUC-Ate-010419	Aspergillus terreus	37.65	3.00e-08	53.10
IUUC-Ame-011606	Astyanax mexicanus	55.64	9.00e-147	514.00
IUUC-Bta-012561	Bos taurus	96.28	0.00e+00	1470.00
IUUC-Bdi-015055	Brachypodium distachyon	43.16	6.00e-13	68.90
IUUC-Bol-015438	Brassica oleracea	38.85	2.00e-15	77.40
IUUC-Bra-017388	Brassica rapa	43.48	3.00e-15	77.00
IUUC-Cja-019188	Callithrix jacchus	87.37	0.00e+00	1311.00
IUUC-Cfa-021178	Canis familiaris	90.70	0.00e+00	1456.00
IUUC-Cpo-022133	Cavia porcellus	90.60	0.00e+00	1415.00
IUUC-Cin-025671	Ciona intestinalis	50.65	5.00e-15	74.30
IUUC-Dre-028559	Danio rerio	54.44	3.00e-153	536.00
IUUC-Dno-029388	Dasypus novemcinctus	87.12	0.00e+00	1401.00
IUUC-Dor-030577	Dipodomys ordii	86.73	0.00e+00	867.00
IUUC-Dme-031599	Drosophila melanogaster	43.53	3.00e-17	84.70
IUUC-Ete-032733	Echinops telfairi	95.02	1.00e-157	550.00
IUUC-Eca-033397	Equus caballus	96.03	0.00e+00	1449.00
IUUC-Eeu-034638	Erinaceus europaeus	97.93	0.00e+00	704.00
IUUC-Fca-036518	Felis catus	91.73	0.00e+00	1480.00
IUUC-Gmo-038892	Gadus morhua	48.02	7.00e-119	421.00
IUUC-Ggr-039961	Gaeumannomyces graminis	36.00	2.00e-07	50.10
IUUC-Gac-041284	Gasterosteus aculeatus	49.91	1.00e-129	457.00
IUUC-Gma-043850	Glycine max	45.57	1.00e-14	75.10
IUUC-Ggo-044420	Gorilla gorilla	90.04	0.00e+00	1408.00
IUUC-Hsa-046336	Homo sapiens	91.28	0.00e+00	1384.00
IUUC-Hvu-047806	Hordeum vulgare	44.74	1.00e-12	68.60
IUUC-Itr-048007	Ictidomys tridecemlineatus	94.01	0.00e+00	761.00
IUUC-Lch-049762	Latimeria chalumnae	53.93	3.00e-118	419.00
IUUC-Lpe-051531	Leersia perrieri	41.67	6.00e-12	66.20
IUUC-Laf-053832	Loxodonta africana	92.72	0.00e+00	724.00
IUUC-Mcc-055256	Macaca mulatta	88.67	0.00e+00	1377.00
IUUC-Meu-056280	Macropus eugenii	73.93	1.00e-157	550.00
IUUC-Mtr-058642	Medicago truncatula	37.50	4.00e-16	80.10
IUUC-Mmr-061073	Microcebus murinus	90.03	0.00e+00	1434.00
IUUC-Mdo-062059	Monodelphis domestica	78.37	0.00e+00	932.00
IUUC-Mmu-063815	Mus musculus	92.09	0.00e+00	730.00
IUUC-Mac-064677	Musa acuminata	35.37	2.00e-05	45.10
IUUC-Mpu-066558	Mustela putorius furo	94.70	0.00e+00	1489.00
IUUC-Mlu-067697	Myotis lucifugus	93.21	0.00e+00	1145.00
IUUC-Nfi-068487	Neosartorya fischeri	34.48	9.00e-09	54.70
IUUC-Nle-068988	Nomascus leucogenys	88.58	0.00e+00	1355.00
IUUC-Opr-071123	Ochotona princeps	86.43	0.00e+00	1348.00
IUUC-Ont-072239	Oreochromis niloticus	53.02	4.00e-122	432.00
IUUC-Ocu-073903	Oryctolagus cuniculus	88.75	0.00e+00	1404.00
IUUC-Oba-075736	Oryza barthii	42.27	5.00e-13	69.30
IUUC-Obr-076574	Oryza brachyantha	42.45	3.00e-13	69.70
IUUC-Ogl-077678	Oryza glaberrima	42.27	5.00e-13	69.30
IUUC-Ogu-078952	Oryza glumaepatula	42.27	6.00e-13	69.30
IUUC-Oin-079943	Oryza indica	42.27	6.00e-13	68.90
IUUC-Ome-081937	Oryza meridionalis	42.27	8.00e-13	68.90
IUUC-Oni-082471	Oryza nivara	42.27	5.00e-13	69.30
IUUC-Opu-083366	Oryza punctata	42.27	6.00e-13	69.30
IUUC-Oru-085170	Oryza rufipogon	42.27	6.00e-13	69.30
IUUC-Osa-085915	Oryza sativa	44.57	4.00e-13	68.20
IUUC-Ola-087116	Oryzias latipes	47.03	3.00e-114	406.00
IUUC-Oga-088614	Otolemur garnettii	93.21	0.00e+00	1452.00
IUUC-Oar-090085	Ovis aries	91.07	0.00e+00	1381.00
IUUC-Pan-091999	Papio anubis	91.85	0.00e+00	1392.00
IUUC-Ppa-095775	Physcomitrella patens	38.93	1.00e-16	82.00
IUUC-Pfo-097252	Poecilia formosa	48.78	2.00e-124	440.00
IUUC-Pab-098493	Pongo abelii	92.12	0.00e+00	1399.00
IUUC-Pop-099480	Populus trichocarpa	49.43	1.00e-16	82.40
IUUC-Ppe-101620	Prunus persica	46.58	5.00e-13	70.10
IUUC-Pva-103214	Pteropus vampyrus	92.41	0.00e+00	752.00
IUUC-Rno-105636	Rattus norvegicus	90.58	0.00e+00	719.00
IUUC-Sha-106964	Sarcophilus harrisii	79.28	0.00e+00	666.00
IUUC-Smo-108818	Selaginella moellendorffii	38.79	1.00e-13	71.60
IUUC-Sit-109935	Setaria italica	42.68	5.00e-12	66.60
IUUC-Sly-111457	Solanum lycopersicum	48.78	2.00e-15	77.40
IUUC-Sar-113198	Sorex araneus	97.78	9.00e-165	574.00
IUUC-Sbi-114712	Sorghum bicolor	43.62	2.00e-12	67.80
IUUC-Tru-118440	Takifugu rubripes	51.97	8.00e-110	391.00
IUUC-Tsy-119351	Tarsius syrichta	87.62	0.00e+00	674.00
IUUC-Tca-121642	Theobroma cacao	47.44	4.00e-14	73.60
IUUC-Tae-125387	Triticum aestivum	44.74	1.00e-12	68.60
IUUC-Tbe-127897	Tupaia belangeri	97.60	5.00e-152	531.00
IUUC-Ttr-128389	Tursiops truncatus	94.24	0.00e+00	1417.00
IUUC-Vvi-130920	Vitis vinifera	48.00	1.00e-14	75.10
IUUC-Xtr-132680	Xenopus tropicalis	57.23	9.00e-146	511.00
IUUC-Xma-133181	Xiphophorus maculatus	57.98	9.00e-51	194.00
IUUC-Yli-134630	Yarrowia lipolytica	37.66	4.00e-10	58.50

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence