iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067210

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02044667

Gene Name

KLHL40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000001619.2	ENSMLUT00000001615.2	ENSMLUP00000001484.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.20e-14	53.6	34	98
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.00e-07	29.0	130	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D+++ vg++ef++h++vLaa+S++F+a fl e e     ++  +++v p+v+ ++l++lYt++++++e
   Q: 34   DCVVRVGEREFPCHRLVLAACSPYFRARFLAEPEPA---GELRLEEVAPDVVAQVLHYLYTSEITLDE 98
           9****************************9988865...689999******************98865 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           l+Ncl+++r++ l+dc +L+ aa+dfi+  F+
   Q: 130  LSNCLAVFRLGLLLDCARLAVAARDFICARFP 161
           69***************************995 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MALGLEQAEE QRLYQQTLLQ DGLKDMLDHG KFLDCVVRVG EREFPCHRLV LAACSPYFRA 60
RFLAEPEPAG ELRLEEVAPD VVAQVLHYLY TSEITLDEAS VQDLFAAAHR FQIPSIFTIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCCGCTCA CCATGGCGCT GGGCTTGGAG CAGGCGGAGG AGCAGCGGCT GTACCAGCAG 60
ACGCTCCTGC AGGACGGGCT CAAGGACATG CTGGACCACG GCAAGTTCCT GGACTGCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030607--KLHL40
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031397--P:negative regulation of protein ubiquitination
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001792	Ailuropoda melanoleuca	88.78	0.00e+00	1065.00
IUUC-Apl-003748	Anas platyrhynchos	71.84	0.00e+00	907.00
IUUC-Aca-005275	Anolis carolinensis	64.06	0.00e+00	818.00
IUUC-Acl-008133	Aspergillus clavatus	32.26	2.00e-03	37.00
IUUC-Ame-011294	Astyanax mexicanus	57.19	0.00e+00	728.00
IUUC-Bta-012801	Bos taurus	92.79	0.00e+00	1142.00
IUUC-Cja-019795	Callithrix jacchus	91.48	0.00e+00	1012.00
IUUC-Cfa-021245	Canis familiaris	88.57	0.00e+00	783.00
IUUC-Cpo-022436	Cavia porcellus	88.76	0.00e+00	1135.00
IUUC-Csa-023105	Chlorocebus sabaeus	92.46	0.00e+00	1134.00
IUUC-Dre-028603	Danio rerio	57.76	0.00e+00	751.00
IUUC-Dno-030015	Dasypus novemcinctus	77.37	0.00e+00	642.00
IUUC-Eca-034393	Equus caballus	92.62	0.00e+00	1069.00
IUUC-Fca-035823	Felis catus	82.81	0.00e+00	1004.00
IUUC-Fal-037632	Ficedula albicollis	72.96	0.00e+00	894.00
IUUC-Gmo-039697	Gadus morhua	57.89	0.00e+00	747.00
IUUC-Gga-040525	Gallus gallus	72.32	0.00e+00	913.00
IUUC-Gac-042421	Gasterosteus aculeatus	60.86	0.00e+00	776.00
IUUC-Ggo-045596	Gorilla gorilla	92.46	0.00e+00	1130.00
IUUC-Hsa-046235	Homo sapiens	92.30	0.00e+00	1126.00
IUUC-Itr-048612	Ictidomys tridecemlineatus	93.26	0.00e+00	1178.00
IUUC-Lch-050123	Latimeria chalumnae	65.16	0.00e+00	870.00
IUUC-Loc-051824	Lepisosteus oculatus	63.41	0.00e+00	833.00
IUUC-Laf-053485	Loxodonta africana	87.86	0.00e+00	720.00
IUUC-Mcc-054909	Macaca mulatta	92.30	0.00e+00	1132.00
IUUC-Meu-055972	Macropus eugenii	75.80	0.00e+00	970.00
IUUC-Mga-059451	Meleagris gallopavo	72.64	0.00e+00	924.00
IUUC-Mmr-060736	Microcebus murinus	91.65	0.00e+00	1155.00
IUUC-Mdo-062563	Monodelphis domestica	77.31	0.00e+00	764.00
IUUC-Mmu-063549	Mus musculus	92.62	0.00e+00	1158.00
IUUC-Mpu-066262	Mustela putorius furo	93.59	0.00e+00	1148.00
IUUC-Nle-069300	Nomascus leucogenys	90.91	0.00e+00	792.00
IUUC-Opr-070384	Ochotona princeps	85.90	0.00e+00	1031.00
IUUC-Ont-071273	Oreochromis niloticus	60.54	0.00e+00	762.00
IUUC-Ocu-074499	Oryctolagus cuniculus	91.71	0.00e+00	1123.00
IUUC-Ola-087175	Oryzias latipes	59.81	0.00e+00	762.00
IUUC-Oga-088855	Otolemur garnettii	91.17	0.00e+00	1151.00
IUUC-Oar-089342	Ovis aries	80.13	0.00e+00	908.00
IUUC-Ptr-091028	Pan troglodytes	90.89	0.00e+00	776.00
IUUC-Pan-091827	Papio anubis	92.62	0.00e+00	1134.00
IUUC-Psi-092998	Pelodiscus sinensis	72.80	0.00e+00	915.00
IUUC-Pma-094586	Petromyzon marinus	57.95	1.00e-95	342.00
IUUC-Pfo-096216	Poecilia formosa	58.47	0.00e+00	769.00
IUUC-Pab-097656	Pongo abelii	90.23	0.00e+00	680.00
IUUC-Pva-102331	Pteropus vampyrus	83.01	0.00e+00	1011.00
IUUC-Pte-104085	Pyrenophora teres	35.29	1.00e-04	41.20
IUUC-Pyt-104655	Pyrenophora triticirepentis	35.29	9.00e-05	41.20
IUUC-Rno-105613	Rattus norvegicus	91.80	0.00e+00	1029.00
IUUC-Sha-107091	Sarcophilus harrisii	77.64	0.00e+00	1008.00
IUUC-Sar-112941	Sorex araneus	89.14	0.00e+00	783.00
IUUC-Ssc-116276	Sus scrofa	93.91	0.00e+00	1152.00
IUUC-Tgu-116494	Taeniopygia guttata	72.48	0.00e+00	929.00
IUUC-Tru-118614	Takifugu rubripes	59.90	0.00e+00	786.00
IUUC-Tsy-119499	Tarsius syrichta	90.79	0.00e+00	654.00
IUUC-Tni-119776	Tetraodon nigroviridis	60.06	0.00e+00	771.00
IUUC-Tbe-127806	Tupaia belangeri	83.79	0.00e+00	1032.00
IUUC-Ttr-128813	Tursiops truncatus	90.69	0.00e+00	1140.00
IUUC-Vpa-130127	Vicugna pacos	94.30	0.00e+00	695.00
IUUC-Xtr-132942	Xenopus tropicalis	67.46	0.00e+00	873.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence