iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000012790.3	ENSSSCT00000036605.1	ENSSSCP00000030040.1
ENSSSCG00000012790.3	ENSSSCT00000032713.1	ENSSSCP00000031115.1
ENSSSCG00000012790.3	ENSSSCT00000013982.2	ENSSSCP00000013599.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-10	41.5	765	813

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 8    vlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + + y++ +  eLt+++Gdv+++  +e  +++W++g  el+g rGl+P+ +++
   Q: 765  ACFAYTGRTAQELTFQRGDVLRL--HERASGDWWRG--ELAGARGLIPHKYIT 813
           789********************..59*********..9************96 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MATHGKLRRE RGPQAEYEAQ VKEMRWQLGE QLRCLELQGE LRRELLQELA EFMRRRAEVE 60
LEYSRGLDRL AERFSGRAGR LGGSGREHQS FRKEPSLLSP LHCWAVLLQQ TRQQSRESAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCCGGGCC CGCTCACGGC CGCGTGGGAA GAGCGGGGCT CGACGGCGCG GCCGCCGGGC 60
GGCCATGGCC ACGCACGGGA AGCTGCGCCG GGAGCGAGGG CCGCAGGCCG AGTATGAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00611--FCH
PF00620--RhoGAP
PF00018--SH3_1

SMART

SM00055--FCH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005096--F:GTPase activator activity
GO:0048365--F:Rac GTPase binding
GO:0030336--P:negative regulation of cell migration
GO:0007165--P:signal transduction

KEGG

ssc:100523659

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011131	Astyanax mexicanus	47.96	0.00e+00	692.00
IUUC-Bta-012780	Bos taurus	86.71	0.00e+00	1394.00
IUUC-Gac-042431	Gasterosteus aculeatus	33.16	2.00e-24	107.00
IUUC-Hsa-045896	Homo sapiens	87.39	3.00e-51	194.00
IUUC-Mmu-064211	Mus musculus	78.07	2.00e-37	148.00
IUUC-Ont-071342	Oreochromis niloticus	32.26	5.00e-22	99.40
IUUC-Pma-094731	Petromyzon marinus	31.90	3.00e-22	101.00
IUUC-Tru-118770	Takifugu rubripes	45.25	0.00e+00	671.00
IUUC-Tni-120458	Tetraodon nigroviridis	33.51	1.00e-24	108.00
IUUC-Tbe-128126	Tupaia belangeri	28.65	9.00e-10	58.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence