iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092165

Ensembl Protein ID

ENSPANP00000001997.1

UniProt Accession

A0A096MQG9; A0A096MQG9_PAPAN

Genbank Protein ID

ENSPANP00000001997

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01068360

Gene Name

TRIM68

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000004042.1	ENSPANT00000007137.1	ENSPANP00000001997.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.70e-09	36.4	16	61
E3 activity/RING/U-box	6.30e-06	26.2	10	81

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw..pglknssskefrCPlCr 46
           C+iC++ +++ p++ +CgH f+++Cl   w  pg +  ++   +CPlCr
   Q: 16   CPICMTFLRE-PVSIDCGHSFCHSCLsGLWeiPGES--QNWGYTCPLCR 61
           ********88.***************8788544444..78888*****8 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwl...asggk......tcPvtrqplteedlvPnltlrrliqa 67
           + ee  CpI ++  r+Pv + +G+++  s++           +      tcP++r+p+++++l Pn  l +++++
   Q: 10   IVEEVACPICMTFLREPVSIDCGHSFCHSCLSGLWeipG---EsqnwgyTCPLCRAPVQPRNLRPNWQLANVVEK 81
           67999**************************98554441...2355789*****************999888765 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MDPTALVEAI VEEVACPICM TFLREPVSID CGHSFCHSCL SGLWEIPGES QNWGYTCPLC 60
RAPVQPRNLR PNWQLANVVE KVRLLRLHPG MGLKGDLCEC HGEKLKMFCK EDVLIMCEAC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCCCA CAGCCTTGGT GGAAGCCATT GTGGAAGAAG TGGCCTGTCC CATCTGTATG 60
ACCTTCCTGA GGGAGCCTGT GAGCATTGAC TGTGGCCATA GCTTCTGCCA CAGCTGCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005730--C:nucleolus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0051865--P:protein autoubiquitination
GO:0060765--P:regulation of androgen receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002078	Ailuropoda melanoleuca	90.10	0.00e+00	837.00
IUUC-Bta-012800	Bos taurus	84.36	0.00e+00	850.00
IUUC-Cja-019382	Callithrix jacchus	94.43	0.00e+00	872.00
IUUC-Cfa-020686	Canis familiaris	87.47	2.00e-178	618.00
IUUC-Csa-023952	Chlorocebus sabaeus	99.79	0.00e+00	910.00
IUUC-Cho-024811	Choloepus hoffmanni	79.42	0.00e+00	712.00
IUUC-Dno-029361	Dasypus novemcinctus	83.71	0.00e+00	795.00
IUUC-Dor-030703	Dipodomys ordii	82.89	0.00e+00	771.00
IUUC-Ete-033159	Echinops telfairi	88.43	5.00e-115	407.00
IUUC-Eca-033633	Equus caballus	79.96	0.00e+00	707.00
IUUC-Eeu-034686	Erinaceus europaeus	77.89	0.00e+00	720.00
IUUC-Fca-035750	Felis catus	87.89	0.00e+00	815.00
IUUC-Ggo-045524	Gorilla gorilla	98.14	0.00e+00	898.00
IUUC-Hsa-046031	Homo sapiens	97.73	0.00e+00	922.00
IUUC-Itr-048898	Ictidomys tridecemlineatus	82.89	0.00e+00	765.00
IUUC-Laf-054264	Loxodonta africana	86.96	0.00e+00	856.00
IUUC-Mcc-055388	Macaca mulatta	99.79	0.00e+00	910.00
IUUC-Mmr-060612	Microcebus murinus	82.68	0.00e+00	781.00
IUUC-Mmu-063761	Mus musculus	78.10	0.00e+00	773.00
IUUC-Mpu-066319	Mustela putorius furo	90.52	0.00e+00	839.00
IUUC-Mlu-067368	Myotis lucifugus	87.22	0.00e+00	813.00
IUUC-Nle-069702	Nomascus leucogenys	97.53	0.00e+00	892.00
IUUC-Opr-070810	Ochotona princeps	73.07	0.00e+00	640.00
IUUC-Ont-072259	Oreochromis niloticus	33.01	3.00e-68	252.00
IUUC-Oga-088935	Otolemur garnettii	85.15	0.00e+00	786.00
IUUC-Oar-089940	Ovis aries	89.48	0.00e+00	838.00
IUUC-Ptr-091056	Pan troglodytes	97.73	0.00e+00	896.00
IUUC-Pab-098415	Pongo abelii	97.24	4.00e-173	600.00
IUUC-Pca-100470	Procavia capensis	80.04	0.00e+00	807.00
IUUC-Pva-102603	Pteropus vampyrus	83.30	0.00e+00	758.00
IUUC-Rno-105709	Rattus norvegicus	74.89	0.00e+00	717.00
IUUC-Sar-113101	Sorex araneus	78.72	2.00e-149	521.00
IUUC-Ssc-115920	Sus scrofa	85.77	0.00e+00	809.00
IUUC-Tbe-127512	Tupaia belangeri	76.98	7.00e-168	583.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence