iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Rno-105795

UUCD1 version

UUC-RaN-00682

Ensembl Protein ID

ENSRNOP00000015421.6

UniProt Accession

A0A140TAB2; A0A140TAB2_RAT

Genbank Protein ID

ENSRNOP00000015421

Protein Name

E3 ubiquitin-protein ligase RNF146

Genbank Nucleotide ID

AABR07000978

Gene Name

Rnf146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000011588.6	ENSRNOT00000015421.6	ENSRNOP00000015421.6

Annotation

mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	86.67	1.00e-161	566.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MEMMAGCGEI DHSLNMLPTN KKASETCSNT APSLTVPECA ICLQTCVHPV SLPCKHVFCY 60
LCVKGASWLG KRCALCRQEI PEDFLDKPTL LSPEELKAAS RGNGEYVWYY EGRNGWWQYD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGATGAGG AAGTGGCCAG AGGTCTCCAT AACTAAAGAA CAGGTGTGGG AATGCGAACT 60
GATGAGAAGG GCCAGCGCTT GTGGTCTGAG AATGCGATTG TGACTTGTTT TAGATGACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

KEGG

rno:308051

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	87.19	3.00e-147	514.00
IUUC-Apl-004143	Anas platyrhynchos	76.62	3.00e-128	451.00
IUUC-Aca-004557	Anolis carolinensis	75.84	1.00e-122	432.00
IUUC-Ame-011088	Astyanax mexicanus	60.08	1.00e-81	296.00
IUUC-Bta-012639	Bos taurus	88.73	3.00e-144	504.00
IUUC-Cel-018462	Caenorhabditis elegans	27.84	1.00e-18	86.30
IUUC-Cja-019397	Callithrix jacchus	90.28	6.00e-150	523.00
IUUC-Cfa-021140	Canis familiaris	86.67	7.00e-156	543.00
IUUC-Cpo-021387	Cavia porcellus	87.29	1.00e-162	565.00
IUUC-Csa-023503	Chlorocebus sabaeus	88.54	3.00e-147	514.00
IUUC-Cho-024895	Choloepus hoffmanni	86.18	2.00e-130	457.00
IUUC-Cin-025455	Ciona intestinalis	53.21	7.00e-44	169.00
IUUC-Dre-028824	Danio rerio	48.03	4.00e-83	301.00
IUUC-Dno-029269	Dasypus novemcinctus	89.14	2.00e-151	528.00
IUUC-Dor-030592	Dipodomys ordii	89.66	1.00e-159	555.00
IUUC-Dme-031618	Drosophila melanogaster	57.33	2.00e-55	209.00
IUUC-Ete-032478	Echinops telfairi	87.64	1.00e-154	539.00
IUUC-Eca-033389	Equus caballus	89.89	2.00e-167	581.00
IUUC-Fca-035488	Felis catus	89.33	6.00e-151	526.00
IUUC-Fal-037087	Ficedula albicollis	77.75	3.00e-148	517.00
IUUC-Gga-040401	Gallus gallus	82.82	3.00e-133	468.00
IUUC-Gac-042412	Gasterosteus aculeatus	63.16	1.00e-86	313.00
IUUC-Ggo-045417	Gorilla gorilla	91.64	2.00e-146	511.00
IUUC-Hsa-045790	Homo sapiens	90.00	2.00e-149	521.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	91.53	6.00e-160	556.00
IUUC-Lch-049493	Latimeria chalumnae	69.30	8.00e-111	393.00
IUUC-Loc-052927	Lepisosteus oculatus	68.27	1.00e-100	359.00
IUUC-Laf-053904	Loxodonta africana	82.92	6.00e-148	516.00
IUUC-Mcc-055427	Macaca mulatta	86.43	3.00e-150	524.00
IUUC-Mmr-060580	Microcebus murinus	89.64	1.00e-145	509.00
IUUC-Mdo-062094	Monodelphis domestica	94.70	6.00e-77	278.00
IUUC-Mmu-063363	Mus musculus	93.84	2.00e-165	575.00
IUUC-Mpu-066816	Mustela putorius furo	87.43	6.00e-145	506.00
IUUC-Mlu-067433	Myotis lucifugus	87.74	6.00e-166	576.00
IUUC-Nle-068986	Nomascus leucogenys	89.72	9.00e-161	559.00
IUUC-Ont-072670	Oreochromis niloticus	58.18	7.00e-80	290.00
IUUC-Oan-073330	Ornithorhynchus anatinus	86.07	8.00e-106	375.00
IUUC-Ocu-074161	Oryctolagus cuniculus	90.65	3.00e-162	564.00
IUUC-Ola-086902	Oryzias latipes	69.82	4.00e-83	301.00
IUUC-Oga-089159	Otolemur garnettii	89.58	3.00e-172	597.00
IUUC-Oar-089586	Ovis aries	88.52	2.00e-137	481.00
IUUC-Ptr-090987	Pan troglodytes	90.00	2.00e-149	521.00
IUUC-Pan-091867	Papio anubis	86.39	2.00e-149	521.00
IUUC-Psi-094024	Pelodiscus sinensis	82.25	2.00e-134	471.00
IUUC-Pma-094453	Petromyzon marinus	62.72	4.00e-64	238.00
IUUC-Pfo-097108	Poecilia formosa	50.92	3.00e-83	301.00
IUUC-Pab-097997	Pongo abelii	88.30	7.00e-154	536.00
IUUC-Pca-100260	Procavia capensis	83.15	7.00e-149	519.00
IUUC-Pva-103140	Pteropus vampyrus	85.83	7.00e-154	536.00
IUUC-Sha-107033	Sarcophilus harrisii	80.85	8.00e-148	516.00
IUUC-Ssc-116395	Sus scrofa	88.02	7.00e-167	579.00
IUUC-Tgu-116685	Taeniopygia guttata	76.14	1.00e-128	452.00
IUUC-Tru-118014	Takifugu rubripes	65.38	8.00e-84	303.00
IUUC-Tsy-119326	Tarsius syrichta	83.61	2.00e-161	561.00
IUUC-Tni-120322	Tetraodon nigroviridis	70.89	1.00e-81	296.00
IUUC-Tbe-128067	Tupaia belangeri	88.89	2.00e-158	551.00
IUUC-Ttr-128530	Tursiops truncatus	88.89	2.00e-151	528.00
IUUC-Vpa-130322	Vicugna pacos	89.44	5.00e-160	556.00
IUUC-Xtr-132606	Xenopus tropicalis	65.62	8.00e-115	406.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence