iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003734

Ensembl Protein ID

ENSAPLP00000004907.1

UniProt Accession

U3ICD5; U3ICD5_ANAPL

Genbank Protein ID

ENSAPLP00000004907

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01130257

Gene Name

VAV3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000005225.1	ENSAPLT00000005530.1	ENSAPLP00000004907.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.10e-15	54.3	725	776

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ yd+ a +  eL+l kGdvv++   +   +gW++g  e +g+ G fP+ +ve+
   Q: 725  IARYDFCARDMRELSLLKGDVVKIY-TKMSANGWWRG--EVNGRVGWFPSTYVEE 776
           578*********************9.999999*****..9*************86 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

FLCLKNIRTF LSACCEIFGM KKSELFEAFD LFDVRDFGKV IETLSKLSRT PIAIATGIRP 60
FPTEESVDDE DVYKGLPDLI DETGVDEDEE LYDCVYGEDE GGEVYEDLMK DEAAQQPKYT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCTTTGCT TGAAGAACAT AAGGACCTTC CTTTCAGCAT GTTGTGAAAT ATTTGGGATG 60
AAGAAAAGTG AGCTTTTTGA AGCATTCGAT TTGTTTGATG TAAGAGACTT TGGAAAGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001362	Ailuropoda melanoleuca	87.03	0.00e+00	1331.00
IUUC-Aca-004477	Anolis carolinensis	85.86	0.00e+00	1338.00
IUUC-Ath-007340	Arabidopsis thaliana	50.00	1.20e-02	33.90
IUUC-Ame-011279	Astyanax mexicanus	65.90	0.00e+00	1005.00
IUUC-Bta-012722	Bos taurus	86.39	0.00e+00	1327.00
IUUC-Cel-018578	Caenorhabditis elegans	28.26	1.00e-83	304.00
IUUC-Cja-018941	Callithrix jacchus	86.78	0.00e+00	1330.00
IUUC-Cfa-020266	Canis familiaris	87.50	0.00e+00	1301.00
IUUC-Cpo-021966	Cavia porcellus	86.38	0.00e+00	1262.00
IUUC-Csa-023892	Chlorocebus sabaeus	86.65	0.00e+00	1329.00
IUUC-Dre-028199	Danio rerio	65.96	0.00e+00	1018.00
IUUC-Dno-029474	Dasypus novemcinctus	86.91	0.00e+00	1332.00
IUUC-Eca-033961	Equus caballus	87.37	0.00e+00	1326.00
IUUC-Eeu-034719	Erinaceus europaeus	69.07	0.00e+00	715.00
IUUC-Fca-036572	Felis catus	86.78	0.00e+00	1323.00
IUUC-Fal-036802	Ficedula albicollis	94.04	0.00e+00	1494.00
IUUC-Gmo-039409	Gadus morhua	67.94	0.00e+00	1045.00
IUUC-Gga-040884	Gallus gallus	96.92	0.00e+00	1503.00
IUUC-Gac-041395	Gasterosteus aculeatus	71.52	0.00e+00	1141.00
IUUC-Ggo-044460	Gorilla gorilla	84.65	0.00e+00	1256.00
IUUC-Hsa-046099	Homo sapiens	83.77	0.00e+00	1315.00
IUUC-Itr-048144	Ictidomys tridecemlineatus	83.27	0.00e+00	1271.00
IUUC-Lch-049650	Latimeria chalumnae	84.51	5.00e-111	392.00
IUUC-Loc-052487	Lepisosteus oculatus	72.61	0.00e+00	1137.00
IUUC-Laf-054564	Loxodonta africana	86.91	0.00e+00	1329.00
IUUC-Mcc-054622	Macaca mulatta	83.52	0.00e+00	1310.00
IUUC-Meu-056680	Macropus eugenii	79.31	0.00e+00	1206.00
IUUC-Mga-060013	Meleagris gallopavo	92.06	0.00e+00	1409.00
IUUC-Mmr-061251	Microcebus murinus	82.57	0.00e+00	1343.00
IUUC-Mdo-061875	Monodelphis domestica	86.89	0.00e+00	1343.00
IUUC-Mmu-063735	Mus musculus	86.65	0.00e+00	1357.00
IUUC-Mpu-065856	Mustela putorius furo	87.16	0.00e+00	1338.00
IUUC-Mlu-068108	Myotis lucifugus	82.78	0.00e+00	1266.00
IUUC-Nle-069863	Nomascus leucogenys	83.02	0.00e+00	1302.00
IUUC-Opr-070372	Ochotona princeps	72.98	0.00e+00	794.00
IUUC-Ont-072286	Oreochromis niloticus	71.99	0.00e+00	1118.00
IUUC-Ocu-074194	Oryctolagus cuniculus	86.91	0.00e+00	1338.00
IUUC-Ola-086336	Oryzias latipes	70.64	0.00e+00	1125.00
IUUC-Oga-089104	Otolemur garnettii	57.98	0.00e+00	886.00
IUUC-Oar-089272	Ovis aries	86.26	0.00e+00	1362.00
IUUC-Ptr-090652	Pan troglodytes	84.38	0.00e+00	1314.00
IUUC-Pan-092550	Papio anubis	83.38	0.00e+00	1271.00
IUUC-Psi-093784	Pelodiscus sinensis	86.01	0.00e+00	1338.00
IUUC-Pfo-097308	Poecilia formosa	69.68	0.00e+00	1127.00
IUUC-Pab-098698	Pongo abelii	84.21	0.00e+00	1312.00
IUUC-Pva-102262	Pteropus vampyrus	86.68	0.00e+00	1273.00
IUUC-Rno-105421	Rattus norvegicus	86.01	0.00e+00	1352.00
IUUC-Sha-107325	Sarcophilus harrisii	87.15	0.00e+00	1367.00
IUUC-Sar-113456	Sorex araneus	81.00	0.00e+00	1256.00
IUUC-Ssc-115338	Sus scrofa	57.82	0.00e+00	892.00
IUUC-Tgu-116595	Taeniopygia guttata	91.81	0.00e+00	1391.00
IUUC-Tru-118577	Takifugu rubripes	66.39	0.00e+00	1087.00
IUUC-Tsy-119429	Tarsius syrichta	80.10	0.00e+00	1210.00
IUUC-Tni-119951	Tetraodon nigroviridis	68.11	0.00e+00	1037.00
IUUC-Tbe-127995	Tupaia belangeri	75.78	2.00e-137	483.00
IUUC-Ttr-128281	Tursiops truncatus	87.03	0.00e+00	1332.00
IUUC-Vpa-130066	Vicugna pacos	47.26	2.00e-34	140.00
IUUC-Xtr-132427	Xenopus tropicalis	71.65	0.00e+00	1164.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence