iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107342

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01019576

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000005370.1	ENSSHAT00000006227.1	ENSSHAP00000006173.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	1.20e-07	31.6	69	122

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 15   lk....vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdg 64
           l+    v p++tVa LK++++   g++p  qr+++ G+ L +d +tL +yg++++
   Q: 69   LHiwlmVRPTMTVASLKDMVFLDYGFHPSLQRWVI-GQRLpRDQDTLHSYGVRQD 122
           3333668****************************.99999*********99643 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MEEKTKKVEE MALKLARAVA GGDEKMAVSC ATWLAKQRAL LTLQLKSEVY PKQEIKLWVG 60
VEDAQMHTLH IWLMVRPTMT VASLKDMVFL DYGFHPSLQR WVIGQRLPRD QDTLHSYGVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTATTCTCTA CATCCACGGG TCTCCATCCT CCACTATTTT TCCCACGTCA ATTCCTCGGA 60
TGCTTCTCCC ATCCAATAAG GCTTCTCCGA TTCGTGGCTC CGCCTCCAAG GCCCCGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR029071--Ubiquitin-rel_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

KEGG

shr:100919033

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	77.13	0.00e+00	739.00
IUUC-Apl-003627	Anas platyrhynchos	53.66	2.00e-15	73.20
IUUC-Aca-004507	Anolis carolinensis	66.23	3.00e-169	587.00
IUUC-Ame-011008	Astyanax mexicanus	51.54	7.00e-153	533.00
IUUC-Bta-013247	Bos taurus	76.25	0.00e+00	738.00
IUUC-Cja-018880	Callithrix jacchus	77.71	0.00e+00	744.00
IUUC-Cfa-020477	Canis familiaris	77.71	0.00e+00	732.00
IUUC-Cpo-021558	Cavia porcellus	75.97	0.00e+00	727.00
IUUC-Csa-024129	Chlorocebus sabaeus	76.55	0.00e+00	731.00
IUUC-Cin-025630	Ciona intestinalis	40.00	2.00e-87	316.00
IUUC-Csv-026069	Ciona savignyi	52.40	1.00e-80	292.00
IUUC-Dre-028569	Danio rerio	50.46	9.00e-149	520.00
IUUC-Dno-029015	Dasypus novemcinctus	76.36	0.00e+00	757.00
IUUC-Dor-030313	Dipodomys ordii	69.49	0.00e+00	659.00
IUUC-Ete-032908	Echinops telfairi	68.18	1.00e-178	619.00
IUUC-Eca-034295	Equus caballus	66.99	0.00e+00	655.00
IUUC-Eeu-034454	Erinaceus europaeus	66.67	5.00e-90	324.00
IUUC-Fca-036380	Felis catus	78.29	0.00e+00	755.00
IUUC-Fal-037440	Ficedula albicollis	61.67	4.00e-18	82.00
IUUC-Gmo-038561	Gadus morhua	52.91	2.00e-122	432.00
IUUC-Gga-040198	Gallus gallus	40.89	8.00e-34	137.00
IUUC-Gac-041319	Gasterosteus aculeatus	52.80	5.00e-147	514.00
IUUC-Ggo-044456	Gorilla gorilla	53.82	6.00e-136	477.00
IUUC-Hsa-045738	Homo sapiens	76.55	0.00e+00	730.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	75.78	0.00e+00	733.00
IUUC-Lch-050269	Latimeria chalumnae	45.49	2.00e-126	446.00
IUUC-Loc-052776	Lepisosteus oculatus	64.56	1.00e-117	416.00
IUUC-Laf-054269	Loxodonta africana	75.39	0.00e+00	731.00
IUUC-Mcc-055669	Macaca mulatta	77.13	0.00e+00	735.00
IUUC-Mga-059615	Meleagris gallopavo	63.08	5.00e-20	88.20
IUUC-Mmr-061562	Microcebus murinus	77.78	0.00e+00	659.00
IUUC-Mdo-062263	Monodelphis domestica	93.41	0.00e+00	937.00
IUUC-Mmu-064325	Mus musculus	76.55	0.00e+00	735.00
IUUC-Mpu-066385	Mustela putorius furo	77.13	0.00e+00	744.00
IUUC-Mlu-067000	Myotis lucifugus	76.36	0.00e+00	738.00
IUUC-Nle-069812	Nomascus leucogenys	76.94	0.00e+00	728.00
IUUC-Opr-070575	Ochotona princeps	90.20	9.00e-107	380.00
IUUC-Ont-071314	Oreochromis niloticus	50.65	6.00e-139	488.00
IUUC-Ocu-074358	Oryctolagus cuniculus	68.50	0.00e+00	662.00
IUUC-Ola-087012	Oryzias latipes	52.60	1.00e-152	533.00
IUUC-Oga-087986	Otolemur garnettii	75.19	0.00e+00	725.00
IUUC-Oar-089600	Ovis aries	75.00	0.00e+00	748.00
IUUC-Ptr-091224	Pan troglodytes	76.74	0.00e+00	732.00
IUUC-Pan-092739	Papio anubis	77.33	0.00e+00	738.00
IUUC-Pma-094407	Petromyzon marinus	48.30	3.00e-138	485.00
IUUC-Pfo-096767	Poecilia formosa	51.78	1.00e-156	546.00
IUUC-Pab-098627	Pongo abelii	76.36	0.00e+00	724.00
IUUC-Pca-100641	Procavia capensis	76.94	0.00e+00	715.00
IUUC-Pva-102670	Pteropus vampyrus	76.30	0.00e+00	737.00
IUUC-Rno-105504	Rattus norvegicus	75.58	0.00e+00	721.00
IUUC-Sar-113425	Sorex araneus	80.95	1.00e-108	386.00
IUUC-Ssc-115904	Sus scrofa	90.75	2.00e-95	340.00
IUUC-Tru-118096	Takifugu rubripes	52.49	7.00e-147	513.00
IUUC-Tni-120890	Tetraodon nigroviridis	51.68	3.00e-132	464.00
IUUC-Tme-126901	Tuber melanosporum	25.63	3.00e-06	47.40
IUUC-Tbe-127578	Tupaia belangeri	75.99	1.00e-179	622.00
IUUC-Ttr-129107	Tursiops truncatus	76.16	0.00e+00	719.00
IUUC-Vpa-130353	Vicugna pacos	71.94	2.00e-94	339.00
IUUC-Xtr-132168	Xenopus tropicalis	43.61	7.00e-106	377.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence