iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fox-038035

Ensembl Protein ID

FOXG_05999P0

UniProt Accession

A0A0J9UXD1; A0A0J9UXD1_FUSO4

Genbank Protein ID

KNB03538.1

Protein Name

E3 ubiquitin-protein ligase TRIP12

Genbank Nucleotide ID

DS231701

Gene Name

FOXG_19156

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FOXG_05999	FOXG_05999T0	FOXG_05999P0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.70e-79	265.1	348	721

Active Site

Position(s)	Description	Evidence
1836	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvgEegldlgGvtreflallskelqnpdlglflysen.dketlqpnpdsglknp.............ehlklFeflGrllgkalqdgrll 88
           ++ leve+ +E g++l G+t+ef++ +ske+ + +l+l++  ++ ++ + +++ ++gl +              + l lF++lG++++ ++ d+r++
   Q: 348  QSILEVEYFEEVGTGL-GPTLEFYSTVSKEFSKRKLKLWREVDSsGSDE-FVSGATGLFPRpqsdeeagtpngeRILHLFKMLGKFVARSMIDSRII 442
           56799***********.**********************6555524444.334444433334777778899************************** PP
   S: 89   dlplsksfykll....lgkklsledleevdpelykslkeikena......es...................dieelgldltfsvseeilgetkeeeL 156
           dl++++ f++       g+k sl  ++ vdp l++slk ik+ a      ++                    ++  +l+l f+     l+ + + +L
   Q: 443  DLHFNPIFFRIGdavsSGVKPSLGAVKIVDPGLARSLKAIKQFAlakkeiDEdpnrtpaqkvadtenitidGVKLDDLCLDFT-----LPGYPNIQL 534
           *********85444445669*********************998766655115556666666666766666555555666665.....999****** PP
   S: 157  kpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwev 252
             +G++ +Vt++N ++Y ++v++++l +g+++qv+afr+Gf++v+p + ls+Ft+ el +l     e++++e+l + +k ++gy+ ds+++++++++
   Q: 535  EDNGSQKRVTIDNVDSYLEKVIDMTLGSGVRRQVDAFRAGFSQVFPYSALSAFTPDELVTLFGRVdEDWSLETLLDSIKADHGYNMDSKTVKNLLHT 631
           **********************************************************99887768******************************* PP
   S: 253  leefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
           ++ef++ +r++fLqF+Tgs++lP+gGf++l p+++v+ k     + sdd lPs++TC+nyLkLP+Ys+ ei++++L +A++e+  +F+ls
   Q: 632  MSEFDASQRRDFLQFTTGSPKLPIGGFKSLTPMFTVVCKpsehpYISDDYLPSVMTCVNYLKLPDYSTIEIMRKQLFTAVKEGqGAFHLS 721
           *****************************************99999*************************************8899985 PP

Organism

Fusarium oxysporum

Protein Sequence
(Fasta)

MQDTLECADE KQLTDDEDVG ESSALDAIVG ELEEDMEEES TPEDTSAVNM EVATGGHVTA 60
RKEDGTRIAT PTGSGAPSRA GGPSVGTQGT PTPASSSSRP MSYASALQAV PQDWHIEFSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACCCTCGGC TCCTCGACCT CCGCCTGTTG ATGACGAGGA AATGCAGGAT ACACTAGAAT 60
GCGCCGACGA GAAGCAGCTG ACTGATGACG AAGACGTCGG AGAAAGCAGT GCATTGGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom
IPR012677--Nucleotide-bd_a/b_plait

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	39.34	1.00e-111	397.00
IUUC-Aml-001502	Ailuropoda melanoleuca	37.33	5.00e-113	401.00
IUUC-Atr-002821	Amborella trichopoda	40.37	3.00e-112	399.00
IUUC-Apl-003531	Anas platyrhynchos	35.05	4.00e-103	368.00
IUUC-Aca-004521	Anolis carolinensis	35.07	1.00e-38	155.00
IUUC-Aly-005962	Arabidopsis lyrata	40.07	3.00e-112	399.00
IUUC-Ath-006636	Arabidopsis thaliana	39.90	3.00e-112	399.00
IUUC-Ago-007875	Ashbya gossypii	41.49	6.00e-126	444.00
IUUC-Acl-008242	Aspergillus clavatus	63.85	0.00e+00	909.00
IUUC-Afl-008736	Aspergillus flavus	61.36	0.00e+00	848.00
IUUC-Afu-008812	Aspergillus fumigatus	63.09	0.00e+00	872.00
IUUC-Ani-009407	Aspergillus nidulans	60.88	0.00e+00	846.00
IUUC-Ang-009763	Aspergillus niger	61.02	0.00e+00	815.00
IUUC-Aor-009941	Aspergillus oryzae	63.72	0.00e+00	815.00
IUUC-Ate-010459	Aspergillus terreus	60.84	0.00e+00	775.00
IUUC-Ame-011761	Astyanax mexicanus	37.67	2.00e-114	406.00
IUUC-Bgr-012265	Blumeria graminis	69.28	0.00e+00	950.00
IUUC-Bta-013070	Bos taurus	37.03	2.00e-112	399.00
IUUC-Bci-013890	Botrytis cinerea	71.35	0.00e+00	919.00
IUUC-Bdi-014961	Brachypodium distachyon	39.26	7.00e-111	394.00
IUUC-Bol-015942	Brassica oleracea	39.76	7.00e-109	387.00
IUUC-Bra-016849	Brassica rapa	39.41	2.00e-108	386.00
IUUC-Cel-018153	Caenorhabditis elegans	33.39	4.00e-78	285.00
IUUC-Cja-019046	Callithrix jacchus	39.17	6.00e-113	401.00
IUUC-Cfa-020521	Canis familiaris	37.18	2.00e-112	399.00
IUUC-Cpo-021639	Cavia porcellus	39.33	2.00e-112	399.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	39.39	3.00e-97	347.00
IUUC-Csa-023231	Chlorocebus sabaeus	39.17	4.00e-113	401.00
IUUC-Cho-024380	Choloepus hoffmanni	43.67	5.00e-90	325.00
IUUC-Cin-025482	Ciona intestinalis	38.29	9.00e-105	372.00
IUUC-Csv-026121	Ciona savignyi	35.19	1.00e-104	373.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	78.90	0.00e+00	1155.00
IUUC-Cne-026857	Cryptococcus neoformans	46.41	3.00e-153	535.00
IUUC-Cme-027226	Cyanidioschyzon merolae	36.77	3.00e-78	285.00
IUUC-Dre-028174	Danio rerio	37.33	2.00e-113	402.00
IUUC-Dno-029954	Dasypus novemcinctus	33.96	1.00e-37	151.00
IUUC-Dor-030939	Dipodomys ordii	33.23	6.00e-92	331.00
IUUC-Dse-031444	Dothistroma septosporum	65.36	0.00e+00	905.00
IUUC-Dme-031739	Drosophila melanogaster	31.59	5.00e-80	292.00
IUUC-Ete-032345	Echinops telfairi	33.83	4.00e-85	308.00
IUUC-Eca-033229	Equus caballus	39.17	4.00e-113	402.00
IUUC-Eeu-035205	Erinaceus europaeus	37.03	5.00e-111	394.00
IUUC-Fca-036444	Felis catus	37.73	2.00e-113	402.00
IUUC-Fal-037131	Ficedula albicollis	36.87	6.00e-114	404.00
IUUC-Fso-038320	Fusarium solani	93.20	0.00e+00	1325.00
IUUC-Gmo-039497	Gadus morhua	37.18	2.00e-112	399.00
IUUC-Ggr-040057	Gaeumannomyces graminis	70.65	0.00e+00	1025.00
IUUC-Gga-041021	Gallus gallus	37.03	3.00e-114	405.00
IUUC-Gac-042474	Gasterosteus aculeatus	37.03	2.00e-113	403.00
IUUC-Gma-043060	Glycine max	40.58	2.00e-113	402.00
IUUC-Ggo-044855	Gorilla gorilla	39.17	5.00e-113	401.00
IUUC-Hsa-046147	Homo sapiens	39.17	7.00e-113	401.00
IUUC-Hvu-047775	Hordeum vulgare	38.46	6.00e-109	387.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	39.17	2.00e-112	399.00
IUUC-Kpa-049098	Komagataella pastoris	44.86	2.00e-131	462.00
IUUC-Lch-049818	Latimeria chalumnae	39.81	2.00e-105	376.00
IUUC-Lpe-051017	Leersia perrieri	39.21	8.00e-108	384.00
IUUC-Loc-051777	Lepisosteus oculatus	37.08	5.00e-115	408.00
IUUC-Lma-052990	Leptosphaeria maculans	64.72	0.00e+00	944.00
IUUC-Laf-053727	Loxodonta africana	37.33	4.00e-113	402.00
IUUC-Mcc-055799	Macaca mulatta	39.17	3.00e-113	402.00
IUUC-Meu-056065	Macropus eugenii	33.33	2.00e-85	310.00
IUUC-Mor-057054	Magnaporthe oryzae	72.16	0.00e+00	1051.00
IUUC-Mpo-057417	Magnaporthe poae	73.31	0.00e+00	1045.00
IUUC-Mtr-057849	Medicago truncatula	40.48	2.00e-113	402.00
IUUC-Mla-058870	Melampsora laricipopulina	43.52	1.00e-148	519.00
IUUC-Mga-059409	Meleagris gallopavo	31.93	6.00e-46	179.00
IUUC-Mvi-060507	Microbotryum violaceum	43.42	3.00e-164	571.00
IUUC-Mmr-060816	Microcebus murinus	38.17	3.00e-111	395.00
IUUC-Mdo-062866	Monodelphis domestica	33.61	1.00e-86	313.00
IUUC-Mmu-063906	Mus musculus	37.18	3.00e-112	399.00
IUUC-Mac-064675	Musa acuminata	40.70	2.00e-112	397.00
IUUC-Mpu-066199	Mustela putorius furo	37.33	4.00e-113	402.00
IUUC-Mlu-067110	Myotis lucifugus	38.67	1.00e-110	393.00
IUUC-Nfi-068482	Neosartorya fischeri	61.97	0.00e+00	875.00
IUUC-Ncr-068906	Neurospora crassa	74.00	0.00e+00	1051.00
IUUC-Nle-069410	Nomascus leucogenys	39.17	5.00e-113	401.00
IUUC-Opr-070401	Ochotona princeps	41.67	1.00e-52	201.00
IUUC-Ont-072100	Oreochromis niloticus	36.17	7.00e-111	394.00
IUUC-Oan-073121	Ornithorhynchus anatinus	36.57	1.00e-112	400.00
IUUC-Ocu-074623	Oryctolagus cuniculus	39.33	1.00e-113	403.00
IUUC-Oba-075380	Oryza barthii	34.89	7.00e-103	367.00
IUUC-Obr-076915	Oryza brachyantha	39.18	5.00e-106	378.00
IUUC-Ogl-077055	Oryza glaberrima	39.22	1.00e-105	376.00
IUUC-Ogu-078892	Oryza glumaepatula	34.89	6.00e-104	370.00
IUUC-Oin-079256	Oryza indica	38.66	7.00e-104	370.00
IUUC-Olo-080343	Oryza longistaminata	38.32	6.00e-104	371.00
IUUC-Ome-081422	Oryza meridionalis	38.32	9.00e-104	370.00
IUUC-Oni-083047	Oryza nivara	34.89	9.00e-106	377.00
IUUC-Opu-083641	Oryza punctata	35.24	2.00e-102	365.00
IUUC-Oru-084439	Oryza rufipogon	34.89	8.00e-104	370.00
IUUC-Osa-085972	Oryza sativa	38.71	9.00e-105	372.00
IUUC-Ola-087173	Oryzias latipes	36.17	9.00e-111	394.00
IUUC-Olu-087871	Ostreococcus lucimarinus	38.61	6.00e-99	352.00
IUUC-Oga-087908	Otolemur garnettii	37.18	4.00e-112	398.00
IUUC-Oar-090277	Ovis aries	37.03	2.00e-112	399.00
IUUC-Ptr-091543	Pan troglodytes	39.17	6.00e-113	401.00
IUUC-Pan-092243	Papio anubis	39.17	4.00e-113	402.00
IUUC-Psi-093150	Pelodiscus sinensis	36.87	1.00e-112	400.00
IUUC-Pno-094891	Phaeosphaeria nodorum	64.30	0.00e+00	911.00
IUUC-Ppa-095181	Physcomitrella patens	42.47	5.00e-108	383.00
IUUC-Pfo-096267	Poecilia formosa	36.42	1.00e-111	397.00
IUUC-Pab-098072	Pongo abelii	39.17	6.00e-113	401.00
IUUC-Pop-099541	Populus trichocarpa	38.95	9.00e-111	394.00
IUUC-Pca-100311	Procavia capensis	41.45	1.00e-112	400.00
IUUC-Ppe-101284	Prunus persica	39.76	2.00e-114	405.00
IUUC-Pva-102215	Pteropus vampyrus	36.00	8.00e-97	347.00
IUUC-Pgr-103694	Puccinia graminis	46.48	2.00e-157	548.00
IUUC-Ptt-103916	Puccinia triticina	44.66	4.00e-148	518.00
IUUC-Pte-104346	Pyrenophora teres	64.20	0.00e+00	920.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	64.61	0.00e+00	921.00
IUUC-Rno-105315	Rattus norvegicus	37.48	4.00e-113	402.00
IUUC-Sce-106273	Saccharomyces cerevisiae	41.53	1.00e-116	412.00
IUUC-Sha-106835	Sarcophilus harrisii	36.57	1.00e-111	397.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	46.56	1.00e-140	492.00
IUUC-Spo-108081	Schizosaccharomyces pombe	45.56	9.00e-139	486.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	71.76	0.00e+00	944.00
IUUC-Smo-109590	Selaginella moellendorffii	40.22	7.00e-108	384.00
IUUC-Sit-110717	Setaria italica	38.93	4.00e-112	398.00
IUUC-Sly-111557	Solanum lycopersicum	40.65	1.00e-114	406.00
IUUC-Stu-112896	Solanum tuberosum	36.86	6.00e-105	373.00
IUUC-Sar-113224	Sorex araneus	44.35	9.00e-83	301.00
IUUC-Sbi-113884	Sorghum bicolor	40.03	2.00e-112	399.00
IUUC-Sre-114993	Sporisorium reilianum	44.28	9.00e-157	546.00
IUUC-Ssc-115535	Sus scrofa	35.32	3.00e-90	325.00
IUUC-Tgu-117167	Taeniopygia guttata	33.33	7.00e-39	154.00
IUUC-Tru-118669	Takifugu rubripes	36.78	2.00e-112	399.00
IUUC-Tsy-119373	Tarsius syrichta	32.58	9.00e-71	261.00
IUUC-Tni-120049	Tetraodon nigroviridis	34.53	1.00e-81	295.00
IUUC-Tca-121779	Theobroma cacao	39.35	4.00e-108	385.00
IUUC-Tre-122195	Trichoderma reesei	76.63	0.00e+00	1124.00
IUUC-Tvi-122650	Trichoderma virens	75.81	0.00e+00	1134.00
IUUC-Tae-123120	Triticum aestivum	39.77	2.00e-111	396.00
IUUC-Tur-126295	Triticum urartu	38.99	2.00e-110	392.00
IUUC-Tme-126964	Tuber melanosporum	66.27	0.00e+00	882.00
IUUC-Tbe-128149	Tupaia belangeri	39.71	9.00e-66	244.00
IUUC-Ttr-128165	Tursiops truncatus	39.17	3.00e-113	402.00
IUUC-Uma-129365	Ustilago maydis	44.71	6.00e-150	524.00
IUUC-Vda-129725	Verticillium dahliae	81.64	0.00e+00	1009.00
IUUC-Vpa-130678	Vicugna pacos	38.83	1.00e-112	400.00
IUUC-Vvi-131147	Vitis vinifera	39.86	7.00e-113	400.00
IUUC-Xtr-132636	Xenopus tropicalis	39.71	2.00e-107	383.00
IUUC-Xma-133458	Xiphophorus maculatus	36.57	3.00e-112	399.00
IUUC-Yli-134481	Yarrowia lipolytica	45.92	2.00e-153	535.00
IUUC-Zma-135657	Zea mays	40.13	6.00e-112	397.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence