iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066216

Ensembl Protein ID

ENSMPUP00000016128.1

UniProt Accession

M3YXR8; M3YXR8_MUSPF

Genbank Protein ID

ENSMPUP00000016128

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01076723

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000016232.1	ENSMPUT00000016372.1	ENSMPUP00000016128.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	95.09	0.00e+00	926.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MVDTETLICP LSPLEAEDLE SPLSEEFLQE MGNIQEISQS IGEDSSGSFS FAEYQYLGSG 60
PGSDGSVITD TLSPASSPSS VTYPVAAGSA DEPSSIALNI ECRICGDKAS GYHYGVHACE 120

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Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNACC CACGGCGGCC 60
GACCCGCTGC GTGCCCGCGC GCTCCTCAGC TAGTTTTCAA GTTTAAAGGA GGGCGGCGTG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	96.60	0.00e+00	946.00
IUUC-Apl-003330	Anas platyrhynchos	87.71	0.00e+00	834.00
IUUC-Aca-004598	Anolis carolinensis	85.26	0.00e+00	817.00
IUUC-Acl-008339	Aspergillus clavatus	45.45	1.40e-01	29.60
IUUC-Ame-011508	Astyanax mexicanus	73.40	0.00e+00	700.00
IUUC-Bta-012621	Bos taurus	94.87	0.00e+00	894.00
IUUC-Cja-019688	Callithrix jacchus	94.23	0.00e+00	885.00
IUUC-Cfa-020859	Canis familiaris	97.01	0.00e+00	947.00
IUUC-Cpo-021607	Cavia porcellus	87.61	0.00e+00	832.00
IUUC-Csa-023313	Chlorocebus sabaeus	94.44	0.00e+00	882.00
IUUC-Cho-024741	Choloepus hoffmanni	83.55	0.00e+00	751.00
IUUC-Cgl-026615	Colletotrichum gloeosporioides	34.48	4.10e-01	27.30
IUUC-Dre-027446	Danio rerio	72.13	0.00e+00	686.00
IUUC-Dno-029173	Dasypus novemcinctus	92.52	0.00e+00	867.00
IUUC-Dor-030581	Dipodomys ordii	90.58	0.00e+00	818.00
IUUC-Ete-032330	Echinops telfairi	90.81	0.00e+00	877.00
IUUC-Eca-033712	Equus caballus	94.87	0.00e+00	882.00
IUUC-Fca-036555	Felis catus	97.23	0.00e+00	947.00
IUUC-Fal-036677	Ficedula albicollis	87.61	0.00e+00	832.00
IUUC-Gmo-039240	Gadus morhua	81.02	0.00e+00	638.00
IUUC-Gga-040473	Gallus gallus	88.46	0.00e+00	840.00
IUUC-Gac-041872	Gasterosteus aculeatus	71.88	0.00e+00	700.00
IUUC-Ggo-045226	Gorilla gorilla	95.09	0.00e+00	890.00
IUUC-Hsa-046893	Homo sapiens	95.09	0.00e+00	890.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	91.67	0.00e+00	867.00
IUUC-Lch-050116	Latimeria chalumnae	79.49	0.00e+00	765.00
IUUC-Loc-052131	Lepisosteus oculatus	83.00	0.00e+00	689.00
IUUC-Laf-054323	Loxodonta africana	94.44	0.00e+00	889.00
IUUC-Mcc-054841	Macaca mulatta	95.09	0.00e+00	888.00
IUUC-Meu-056833	Macropus eugenii	83.55	0.00e+00	758.00
IUUC-Mtr-058471	Medicago truncatula	29.82	2.00e-01	30.00
IUUC-Mga-059995	Meleagris gallopavo	79.24	0.00e+00	739.00
IUUC-Mdo-061954	Monodelphis domestica	88.39	0.00e+00	787.00
IUUC-Mmu-064295	Mus musculus	90.60	0.00e+00	825.00
IUUC-Nle-069970	Nomascus leucogenys	94.87	0.00e+00	889.00
IUUC-Ont-071594	Oreochromis niloticus	72.73	0.00e+00	695.00
IUUC-Oan-073501	Ornithorhynchus anatinus	90.95	0.00e+00	763.00
IUUC-Ocu-074634	Oryctolagus cuniculus	83.50	0.00e+00	823.00
IUUC-Oni-082926	Oryza nivara	27.45	1.50e-02	30.40
IUUC-Ola-086585	Oryzias latipes	79.05	0.00e+00	630.00
IUUC-Oga-088738	Otolemur garnettii	95.09	0.00e+00	882.00
IUUC-Oar-090453	Ovis aries	94.87	0.00e+00	892.00
IUUC-Ptr-091518	Pan troglodytes	94.87	0.00e+00	884.00
IUUC-Pan-092006	Papio anubis	94.87	0.00e+00	884.00
IUUC-Psi-093352	Pelodiscus sinensis	86.02	0.00e+00	831.00
IUUC-Pfo-096060	Poecilia formosa	72.52	0.00e+00	683.00
IUUC-Pab-098602	Pongo abelii	88.61	0.00e+00	790.00
IUUC-Pva-102175	Pteropus vampyrus	89.10	0.00e+00	858.00
IUUC-Rno-105283	Rattus norvegicus	91.03	0.00e+00	830.00
IUUC-Sce-106436	Saccharomyces cerevisiae	29.03	1.20e-02	31.20
IUUC-Sha-106560	Sarcophilus harrisii	92.31	0.00e+00	868.00
IUUC-Smo-109075	Selaginella moellendorffii	30.00	8.40e-02	30.00
IUUC-Ssc-115266	Sus scrofa	94.87	0.00e+00	930.00
IUUC-Tgu-116778	Taeniopygia guttata	87.61	0.00e+00	832.00
IUUC-Tru-118436	Takifugu rubripes	71.04	0.00e+00	689.00
IUUC-Tsy-119642	Tarsius syrichta	98.27	3.00e-134	471.00
IUUC-Tni-119859	Tetraodon nigroviridis	71.88	0.00e+00	689.00
IUUC-Tbe-127464	Tupaia belangeri	92.52	0.00e+00	899.00
IUUC-Ttr-129307	Tursiops truncatus	91.26	0.00e+00	844.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence