iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089460

Ensembl Protein ID

ENSOARP00000015375.1

UniProt Accession

W5PY41; W5PY41_SHEEP

Genbank Protein ID

ENSOARP00000015375

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01042964

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000014327.1	ENSOART00000015600.1	ENSOARP00000015375.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.00e-47	162.2	68	257

Active Site

Position(s)	Description	Evidence
75	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
78	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
251		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+ktkgDGnC++rA+++s                                                          ll+vf+d+s sd
   Q: 68   AIRKTKGDGNCFYRALGYSylesllgksreilkfkervlqtpndllaagfeehtfrnffnafysvvelvekdgsvssLLKVFNDQSFSD 156
           79*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
            +v++Lr+lts+++++++dff++fi+e++d+k+fc ++vep+a  +++i+i+aL+q+L+++++v++vd++++    +l++++fpe++ +
   Q: 157  RIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCAHEVEPMAMeCDHIQITALSQALNIALQVEYVDEMDT----ALNHHVFPEAA-T 240
           **********************************************************************95....***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlY+++HY++L+a
   Q: 241  PSVYLLYKTSHYNILYA 257
           ***************97 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

SGRRRAPHRI APRWGGTWPD GSGHYVFQSE TSFNLISEKC DILSILRDHP ENRIYQRKIQ 60
ELSKRFTAIR KTKGDGNCFY RALGYSYLES LLGKSREILK FKERVLQTPN DLLAAGFEEH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTGGGCGCC GCCGCGCCCC CCNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	96.57	3.00e-133	466.00
IUUC-Bta-012766	Bos taurus	99.57	5.00e-137	479.00
IUUC-Cja-019480	Callithrix jacchus	94.42	9.00e-130	455.00
IUUC-Cfa-021106	Canis familiaris	97.00	9.00e-134	468.00
IUUC-Cpo-022187	Cavia porcellus	96.60	8.00e-135	472.00
IUUC-Csa-023493	Chlorocebus sabaeus	95.76	3.00e-133	467.00
IUUC-Cho-024411	Choloepus hoffmanni	77.56	4.00e-86	310.00
IUUC-Dno-029346	Dasypus novemcinctus	97.84	8.00e-134	468.00
IUUC-Dor-031012	Dipodomys ordii	97.00	6.00e-134	469.00
IUUC-Ete-032266	Echinops telfairi	87.93	2.00e-119	421.00
IUUC-Eca-033356	Equus caballus	95.38	7.00e-144	502.00
IUUC-Eeu-034775	Erinaceus europaeus	96.55	5.00e-132	462.00
IUUC-Fca-035363	Felis catus	95.71	9.00e-132	462.00
IUUC-Ggo-045023	Gorilla gorilla	95.71	6.00e-131	459.00
IUUC-Hsa-046984	Homo sapiens	96.14	9.00e-132	462.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	96.14	2.00e-132	464.00
IUUC-Lch-050514	Latimeria chalumnae	61.78	3.00e-83	301.00
IUUC-Loc-052003	Lepisosteus oculatus	50.66	5.00e-64	236.00
IUUC-Laf-054382	Loxodonta africana	96.57	4.00e-133	466.00
IUUC-Mcc-055516	Macaca mulatta	95.73	6.00e-132	462.00
IUUC-Meu-056038	Macropus eugenii	89.42	9.00e-101	358.00
IUUC-Mmr-060918	Microcebus murinus	98.28	4.00e-135	473.00
IUUC-Mdo-062638	Monodelphis domestica	91.38	2.00e-126	444.00
IUUC-Mmu-063973	Mus musculus	95.76	2.00e-133	468.00
IUUC-Mpu-066013	Mustela putorius furo	96.98	4.00e-133	466.00
IUUC-Mlu-067509	Myotis lucifugus	94.42	8.00e-129	452.00
IUUC-Nle-069673	Nomascus leucogenys	96.14	9.00e-132	462.00
IUUC-Opr-070761	Ochotona princeps	88.48	7.00e-81	292.00
IUUC-Oan-072922	Ornithorhynchus anatinus	82.97	1.00e-113	402.00
IUUC-Ocu-074643	Oryctolagus cuniculus	96.14	3.00e-132	463.00
IUUC-Oni-082026	Oryza nivara	28.32	2.00e-16	80.50
IUUC-Oru-084761	Oryza rufipogon	28.32	2.00e-16	80.50
IUUC-Ola-086603	Oryzias latipes	45.37	4.00e-52	197.00
IUUC-Oga-088936	Otolemur garnettii	96.58	2.00e-133	467.00
IUUC-Ptr-090805	Pan troglodytes	95.71	2.00e-131	460.00
IUUC-Pan-091969	Papio anubis	96.14	9.00e-132	462.00
IUUC-Pab-098476	Pongo abelii	95.34	1.00e-132	464.00
IUUC-Pca-100252	Procavia capensis	92.00	2.00e-52	198.00
IUUC-Pva-102204	Pteropus vampyrus	95.71	2.00e-132	464.00
IUUC-Pgr-103552	Puccinia graminis	75.00	2.80e-02	31.20
IUUC-Rno-105062	Rattus norvegicus	96.57	3.00e-133	467.00
IUUC-Sha-106968	Sarcophilus harrisii	90.56	1.00e-126	445.00
IUUC-Sar-113295	Sorex araneus	96.98	4.00e-131	459.00
IUUC-Ssc-115288	Sus scrofa	96.98	2.00e-132	464.00
IUUC-Tni-120440	Tetraodon nigroviridis	39.83	5.00e-44	170.00
IUUC-Tbe-127717	Tupaia belangeri	97.30	7.00e-79	285.00
IUUC-Ttr-128221	Tursiops truncatus	76.72	3.00e-99	354.00
IUUC-Uma-129443	Ustilago maydis	33.49	9.00e-25	107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence