iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133923

Ensembl Protein ID

ENSXMAP00000002443.1

UniProt Accession

M3ZJQ1; M3ZJQ1_XIPMA

Genbank Protein ID

ENSXMAP00000002443

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01006346

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000002424.1	ENSXMAT00000002448.1	ENSXMAP00000002443.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.50e-105	350.9	744	1081

Active Site

Position(s)	Description	Evidence
1049	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +   +++++flGr+lgkal++
   Q: 744  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAEMLVGD-SFTRHYYFLGRILGKALYE 829
           689**********99**9*********************************9999999999999855.9****************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++++f+++llg+  ++++++l+++dpe+y++l ++k++ e d+eelgl++t+   ++ lge++++eLkpgG++ipVt +N
   Q: 830  NMLVELPFASFFLSKLLGTsaDVDIHHLASLDPEMYRNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKPGGKDIPVTTAN 913
           ******************9666889******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i+ ++ afr+G+ +v++le+l++F+++e+++li+G    i ++dlk++t+y ggy++++p+iq Fwev+e+
   Q: 914  RIAYIHLVADYRLNKQIRPHCLAFRQGLANVVNLEWLRMFDQQEIQVLISGAhVPICLDDLKNFTNYSGGYSANHPVIQIFWEVVEG 1000
           ****************************************************999******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd +rlP+++TC+n+LkLPe+  +  +++kLlyAie+++gFels
   Q: 1001 FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlERLPTASTCMNLLKLPEFCDQHLMRSKLLYAIESSAGFELS 1081
           ****************************88.*****99999**************************************985 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MFSFEGDFKT RPKVSLGGAS KKEEKASLLH RTQEERRKRE EERKRLKNAI IIQSYIRGYQ 60
DLKQQYAIQR AKFDESVSQS QAEGTQHVLA ATTLCLLSRR LIFFYRQNVD AHRLIWLCQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCTGTGTT GTGATGATTT CCAGAGTGGA GGAAAAGAAG ACTTGATAAT TGGATTTCTC 60
AGTGTCAGTG TTTCTGTTAC ACTTCGTAGT TTACAAGTTA AAGGTAAGAA GGTTATTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	76.79	0.00e+00	1596.00
IUUC-Apl-003731	Anas platyrhynchos	80.65	0.00e+00	1705.00
IUUC-Aca-005248	Anolis carolinensis	80.52	0.00e+00	1724.00
IUUC-Aly-005768	Arabidopsis lyrata	36.10	5.00e-110	392.00
IUUC-Ath-006576	Arabidopsis thaliana	35.85	1.00e-109	391.00
IUUC-Ago-007748	Ashbya gossypii	42.62	1.00e-79	291.00
IUUC-Acl-008158	Aspergillus clavatus	39.10	7.00e-77	282.00
IUUC-Afl-008398	Aspergillus flavus	39.45	1.00e-78	288.00
IUUC-Afu-008937	Aspergillus fumigatus	39.28	1.00e-78	288.00
IUUC-Ani-009252	Aspergillus nidulans	38.51	6.00e-80	292.00
IUUC-Ang-009773	Aspergillus niger	35.11	3.00e-79	290.00
IUUC-Aor-009940	Aspergillus oryzae	39.45	1.00e-78	288.00
IUUC-Ate-010395	Aspergillus terreus	38.17	4.00e-79	290.00
IUUC-Ame-010769	Astyanax mexicanus	67.82	0.00e+00	1111.00
IUUC-Bgr-012269	Blumeria graminis	38.70	3.00e-76	278.00
IUUC-Bta-012841	Bos taurus	77.37	0.00e+00	1644.00
IUUC-Bci-013743	Botrytis cinerea	38.33	7.00e-84	306.00
IUUC-Bra-016853	Brassica rapa	36.27	7.00e-110	392.00
IUUC-Cel-018638	Caenorhabditis elegans	39.28	5.00e-90	326.00
IUUC-Cja-019743	Callithrix jacchus	76.12	0.00e+00	1603.00
IUUC-Cfa-021031	Canis familiaris	77.94	0.00e+00	1655.00
IUUC-Cpo-022401	Cavia porcellus	79.24	0.00e+00	1657.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.76	7.00e-86	310.00
IUUC-Csa-024107	Chlorocebus sabaeus	78.02	0.00e+00	1665.00
IUUC-Cho-024750	Choloepus hoffmanni	76.67	0.00e+00	743.00
IUUC-Cin-025432	Ciona intestinalis	46.34	9.00e-99	353.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.50	1.00e-86	315.00
IUUC-Cne-026841	Cryptococcus neoformans	35.83	1.00e-94	341.00
IUUC-Cme-027265	Cyanidioschyzon merolae	48.07	1.00e-106	380.00
IUUC-Dre-028196	Danio rerio	84.37	0.00e+00	1729.00
IUUC-Dno-029024	Dasypus novemcinctus	78.20	0.00e+00	1666.00
IUUC-Dor-030483	Dipodomys ordii	82.25	3.00e-175	608.00
IUUC-Dse-031416	Dothistroma septosporum	34.71	3.00e-79	290.00
IUUC-Dme-031946	Drosophila melanogaster	48.28	0.00e+00	629.00
IUUC-Ete-032240	Echinops telfairi	74.93	2.00e-143	503.00
IUUC-Eca-033828	Equus caballus	78.15	0.00e+00	1619.00
IUUC-Eeu-034604	Erinaceus europaeus	81.92	1.00e-121	431.00
IUUC-Fca-035907	Felis catus	77.86	0.00e+00	1656.00
IUUC-Fal-037389	Ficedula albicollis	80.39	0.00e+00	1721.00
IUUC-Fox-037788	Fusarium oxysporum	37.43	1.00e-91	331.00
IUUC-Fso-038088	Fusarium solani	35.77	5.00e-87	316.00
IUUC-Gmo-039254	Gadus morhua	76.41	0.00e+00	1420.00
IUUC-Ggr-039941	Gaeumannomyces graminis	34.84	2.00e-85	311.00
IUUC-Gga-040310	Gallus gallus	80.81	0.00e+00	1721.00
IUUC-Gac-042054	Gasterosteus aculeatus	85.01	0.00e+00	1552.00
IUUC-Gma-042836	Glycine max	35.50	6.00e-102	365.00
IUUC-Ggo-045031	Gorilla gorilla	78.30	0.00e+00	1670.00
IUUC-Hsa-045880	Homo sapiens	78.21	0.00e+00	1669.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	62.09	2.00e-139	488.00
IUUC-Kpa-049307	Komagataella pastoris	37.53	1.00e-66	248.00
IUUC-Lch-050403	Latimeria chalumnae	78.45	0.00e+00	1591.00
IUUC-Loc-052218	Lepisosteus oculatus	85.50	0.00e+00	1786.00
IUUC-Lma-053096	Leptosphaeria maculans	39.31	8.00e-83	302.00
IUUC-Laf-054162	Loxodonta africana	75.28	0.00e+00	1399.00
IUUC-Mcc-055127	Macaca mulatta	78.12	0.00e+00	1668.00
IUUC-Meu-056187	Macropus eugenii	80.43	4.00e-103	369.00
IUUC-Mor-057021	Magnaporthe oryzae	34.08	7.00e-79	289.00
IUUC-Mpo-057570	Magnaporthe poae	36.98	2.00e-78	288.00
IUUC-Mtr-058154	Medicago truncatula	35.53	1.00e-105	377.00
IUUC-Mla-059124	Melampsora laricipopulina	48.03	5.00e-102	364.00
IUUC-Mga-059581	Meleagris gallopavo	80.61	0.00e+00	1702.00
IUUC-Mvi-060445	Microbotryum violaceum	38.31	4.00e-104	373.00
IUUC-Mmr-061360	Microcebus murinus	74.83	0.00e+00	1516.00
IUUC-Mdo-062194	Monodelphis domestica	77.13	0.00e+00	1691.00
IUUC-Mmu-064189	Mus musculus	78.87	0.00e+00	1659.00
IUUC-Mpu-066439	Mustela putorius furo	76.50	0.00e+00	1595.00
IUUC-Mlu-068228	Myotis lucifugus	76.04	0.00e+00	1608.00
IUUC-Nfi-068280	Neosartorya fischeri	39.49	2.00e-79	291.00
IUUC-Ncr-068869	Neurospora crassa	36.32	5.00e-86	313.00
IUUC-Nle-069687	Nomascus leucogenys	77.38	0.00e+00	1611.00
IUUC-Opr-070592	Ochotona princeps	92.50	4.00e-110	392.00
IUUC-Ont-071836	Oreochromis niloticus	93.72	0.00e+00	1968.00
IUUC-Oan-072800	Ornithorhynchus anatinus	80.07	0.00e+00	1725.00
IUUC-Ocu-074587	Oryctolagus cuniculus	78.95	0.00e+00	1682.00
IUUC-Ola-087209	Oryzias latipes	91.78	0.00e+00	1878.00
IUUC-Olu-087699	Ostreococcus lucimarinus	43.94	1.00e-88	319.00
IUUC-Oga-088776	Otolemur garnettii	75.25	0.00e+00	1529.00
IUUC-Oar-089441	Ovis aries	77.26	0.00e+00	1631.00
IUUC-Ptr-091273	Pan troglodytes	78.21	0.00e+00	1669.00
IUUC-Pan-091981	Papio anubis	78.12	0.00e+00	1666.00
IUUC-Psi-093203	Pelodiscus sinensis	78.96	0.00e+00	1471.00
IUUC-Pma-094738	Petromyzon marinus	64.78	0.00e+00	1298.00
IUUC-Pno-095132	Phaeosphaeria nodorum	29.48	2.00e-60	227.00
IUUC-Ppa-095682	Physcomitrella patens	37.18	5.00e-111	395.00
IUUC-Pfo-097511	Poecilia formosa	99.35	0.00e+00	2103.00
IUUC-Pab-098634	Pongo abelii	75.37	0.00e+00	1587.00
IUUC-Pop-098928	Populus trichocarpa	36.14	8.00e-100	358.00
IUUC-Pca-100987	Procavia capensis	92.95	0.00e+00	751.00
IUUC-Pva-103034	Pteropus vampyrus	74.20	0.00e+00	1513.00
IUUC-Pgr-103513	Puccinia graminis	39.42	1.00e-107	384.00
IUUC-Ptt-103967	Puccinia triticina	41.20	7.00e-95	342.00
IUUC-Pte-104105	Pyrenophora teres	35.37	7.00e-82	299.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	35.20	4.00e-80	293.00
IUUC-Rno-105380	Rattus norvegicus	77.78	0.00e+00	1436.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.49	1.00e-69	258.00
IUUC-Sha-107108	Sarcophilus harrisii	73.81	0.00e+00	1548.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	43.90	3.00e-98	353.00
IUUC-Spo-108097	Schizosaccharomyces pombe	43.84	2.00e-97	350.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	30.53	2.00e-84	307.00
IUUC-Sly-111362	Solanum lycopersicum	35.99	3.00e-101	363.00
IUUC-Sar-113687	Sorex araneus	74.91	0.00e+00	830.00
IUUC-Sre-115038	Sporisorium reilianum	43.53	6.00e-99	355.00
IUUC-Ssc-115378	Sus scrofa	89.39	0.00e+00	705.00
IUUC-Tgu-116729	Taeniopygia guttata	80.04	0.00e+00	1708.00
IUUC-Tru-118068	Takifugu rubripes	89.55	0.00e+00	1861.00
IUUC-Tsy-118942	Tarsius syrichta	83.15	6.00e-168	585.00
IUUC-Tni-120732	Tetraodon nigroviridis	86.73	0.00e+00	1820.00
IUUC-Tre-121892	Trichoderma reesei	36.04	4.00e-87	316.00
IUUC-Tvi-122354	Trichoderma virens	35.38	6.00e-89	322.00
IUUC-Tme-127102	Tuber melanosporum	36.51	3.00e-94	340.00
IUUC-Tbe-127351	Tupaia belangeri	68.65	0.00e+00	1280.00
IUUC-Ttr-129061	Tursiops truncatus	75.65	0.00e+00	1585.00
IUUC-Uma-129343	Ustilago maydis	45.32	6.00e-102	365.00
IUUC-Vda-129748	Verticillium dahliae	38.07	1.00e-78	288.00
IUUC-Vvi-131234	Vitis vinifera	35.87	5.00e-103	369.00
IUUC-Xtr-132094	Xenopus tropicalis	80.11	0.00e+00	1656.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence