iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	miRNAMap	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.70e-32	113.1	284	411

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfdddslsdalveaLreltseylqkesdffsefieekedekefcqklvepeakgeeihifaLaqiLs 90
           ++ ++ +DGnCL+rAvs++   v++d+s    l+++Lre+t +y++++ d+fs++ie+  d+ ef+  ++++ a+++  ++ a+ q+L+
   Q: 284  YRFHIIPDGNCLYRAVSKT---VYGDQS----LHRELREQTVHYIADHLDHFSPLIEG--DVGEFIIAAAQDGAWAGYPELLAMGQMLN 363
           78899**************...******....**************************..9**************************** PP
   S: 91   rpiivvdvdsleskvggillpllfpeeklkkpivLlY.rsgHYdaLva 137
           ++i++++  +les++ ++++++l pe++l+++i+L++ ++gHYda+++
   Q: 364  VNIHLTTGGRLESPTVSTMVHYLGPEDSLRPSIWLSWlSNGHYDAVFD 411
           *********************************************986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MQLYSSVCTH YPAGTPGPTA AAPPATTAAF KVSLQSAGPA AAAPEPDTGE RPPAAATEPR 60
EAAAAAAMPA FSACFERSGS ATAAAPPGAC CKPPLPPHFT STAHIAVRAL GAERLLLPPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGCTCT ACAGCAGCGT GTGCACCCAC TACCCTGCGG GCACGCCGGG CCCCACGGCC 60
GCCGCCCCGC CTGCCACCAC CGCCGCCTTC AAGGTCTCCT TGCAGTCAGC GGGCCCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom

PROSITE

PS50802--OTU

Pfam

PF02338--OTU

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003381	Anas platyrhynchos	87.28	8.00e-91	325.00
IUUC-Aca-004882	Anolis carolinensis	69.39	1.00e-78	286.00
IUUC-Ame-011068	Astyanax mexicanus	76.04	1.00e-90	326.00
IUUC-Bta-013311	Bos taurus	95.63	2.00e-119	422.00
IUUC-Cel-018389	Caenorhabditis elegans	37.65	7.00e-10	59.70
IUUC-Cja-019570	Callithrix jacchus	78.30	2.00e-149	522.00
IUUC-Cfa-021137	Canis familiaris	96.98	5.00e-118	417.00
IUUC-Csa-024211	Chlorocebus sabaeus	70.41	8.00e-147	513.00
IUUC-Dre-028539	Danio rerio	76.38	2.00e-93	335.00
IUUC-Fal-037563	Ficedula albicollis	86.60	2.00e-101	361.00
IUUC-Gmo-039313	Gadus morhua	67.53	2.00e-77	281.00
IUUC-Gga-040877	Gallus gallus	86.08	5.00e-101	360.00
IUUC-Gac-042036	Gasterosteus aculeatus	66.67	3.00e-86	310.00
IUUC-Ggo-045008	Gorilla gorilla	72.45	1.00e-145	509.00
IUUC-Hsa-045990	Homo sapiens	72.45	2.00e-146	512.00
IUUC-Lch-049775	Latimeria chalumnae	79.59	6.00e-97	347.00
IUUC-Loc-052017	Lepisosteus oculatus	76.59	7.00e-95	340.00
IUUC-Laf-053375	Loxodonta africana	72.66	7.00e-145	506.00
IUUC-Mcc-055248	Macaca mulatta	73.12	5.00e-148	517.00
IUUC-Mla-058976	Melampsora laricipopulina	38.89	5.00e-09	54.30
IUUC-Mga-059968	Meleagris gallopavo	87.65	4.00e-84	303.00
IUUC-Mmr-061376	Microcebus murinus	76.44	3.00e-71	262.00
IUUC-Mdo-062375	Monodelphis domestica	66.67	1.00e-122	432.00
IUUC-Mmu-063193	Mus musculus	90.65	4.00e-162	564.00
IUUC-Oan-073325	Ornithorhynchus anatinus	83.16	9.00e-100	355.00
IUUC-Oga-087994	Otolemur garnettii	75.70	1.00e-149	522.00
IUUC-Oar-089449	Ovis aries	83.77	1.00e-120	425.00
IUUC-Ptr-090831	Pan troglodytes	72.39	2.00e-146	512.00
IUUC-Pan-091895	Papio anubis	70.41	2.00e-146	512.00
IUUC-Psi-093538	Pelodiscus sinensis	83.00	3.00e-100	357.00
IUUC-Pfo-097114	Poecilia formosa	77.84	4.00e-93	335.00
IUUC-Pab-098228	Pongo abelii	98.83	7.00e-104	368.00
IUUC-Tgu-117161	Taeniopygia guttata	86.22	2.00e-102	363.00
IUUC-Tru-117642	Takifugu rubripes	73.85	3.00e-88	317.00
IUUC-Tsy-119310	Tarsius syrichta	91.67	1.00e-120	426.00
IUUC-Tni-120672	Tetraodon nigroviridis	70.73	3.00e-85	307.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence