iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073336

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01114158

Gene Name

BMI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000005695.4	ENSOANT00000009063.3	ENSOANP00000009061.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.90e-06	27.9	18	57
ULD/UDP/UFD/RAWUL	1.30e-30	106.0	131	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +C   f d + +  C H f+++C+ ++        ++ +CP+C+
   Q: 18   CVLCGGYFIDATTIIECLHSFCKTCIVRY------LETSKYCPICD 57
           ********99999****************......**********5 PP

ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsk..........lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwkkeg 79
           isls+e++++n+ +++ +          ++k+ylrc+a++tV+hl+kfl++k+++++++++d+++e+e+L+d++tL++i+yi++w+++g
   Q: 131  ISLSIEFFDQNRLERKVNkdkekskeevNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNG 219
           7899999999998887768888899999************************************************************* PP
   S: 80   pLvLqYr 86
           pL+L+Yr
   Q: 220  PLPLKYR 226
           ******9 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVRYLETS KYCPICDVQV 60
HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADAANGS NEDRGEVADE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCCTTCT CCCCGCCCCG ACCGCGCCCC GCACCTCGGG GGCGGGGACC GGGCCGCGCC 60
CCGGGGATGA CGGGCGGCGT TTCTGTTTCC CGCAGGACCT CCCCCCAGCC CCCGACCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0000792--C:heterochromatin
GO:0016604--C:nuclear body
GO:0031519--C:PcG protein complex
GO:0000151--C:ubiquitin ligase complex
GO:1990841--F:promoter-specific chromatin binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0008270--F:zinc ion binding
GO:0007420--P:brain development
GO:0006306--P:DNA methylation
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0016574--P:histone ubiquitination
GO:0006959--P:humoral immune response
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030890--P:positive regulation of B cell proliferation
GO:0033092--P:positive regulation of immature T cell proliferation in thymus
GO:2000011--P:regulation of adaxial/abaxial pattern formation
GO:0021903--P:rostrocaudal neural tube patterning
GO:0048103--P:somatic stem cell division

KEGG

oaa:100075752

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001498	Ailuropoda melanoleuca	96.93	1.00e-164	571.00
IUUC-Atr-002463	Amborella trichopoda	35.79	1.00e-11	63.90
IUUC-Apl-004208	Anas platyrhynchos	97.92	1.00e-137	481.00
IUUC-Aca-004661	Anolis carolinensis	84.66	2.00e-139	488.00
IUUC-Ath-007649	Arabidopsis thaliana	39.08	2.00e-12	66.20
IUUC-Ame-010610	Astyanax mexicanus	73.56	3.00e-133	467.00
IUUC-Bta-012606	Bos taurus	97.55	3.00e-166	576.00
IUUC-Bol-015090	Brassica oleracea	36.73	5.00e-13	68.20
IUUC-Cja-019482	Callithrix jacchus	97.45	6.00e-171	592.00
IUUC-Cfa-020482	Canis familiaris	96.93	1.00e-164	571.00
IUUC-Cpo-022061	Cavia porcellus	97.45	5.00e-171	592.00
IUUC-Csa-024102	Chlorocebus sabaeus	97.77	2.00e-172	597.00
IUUC-Cho-025081	Choloepus hoffmanni	80.32	1.00e-110	391.00
IUUC-Cin-025612	Ciona intestinalis	49.07	2.00e-52	199.00
IUUC-Csv-026203	Ciona savignyi	37.26	2.00e-38	150.00
IUUC-Dre-027929	Danio rerio	78.22	8.00e-140	488.00
IUUC-Dno-029797	Dasypus novemcinctus	96.82	1.00e-177	614.00
IUUC-Dor-030256	Dipodomys ordii	94.27	2.00e-158	551.00
IUUC-Dme-031904	Drosophila melanogaster	44.74	5.00e-53	203.00
IUUC-Ete-033148	Echinops telfairi	64.29	2.00e-82	298.00
IUUC-Eca-033318	Equus caballus	97.55	4.00e-166	576.00
IUUC-Eeu-034547	Erinaceus europaeus	84.71	4.00e-141	493.00
IUUC-Fca-035866	Felis catus	97.55	1.00e-165	574.00
IUUC-Fal-036660	Ficedula albicollis	97.85	2.00e-161	560.00
IUUC-Gmo-039341	Gadus morhua	82.69	7.00e-126	442.00
IUUC-Gga-040611	Gallus gallus	97.45	1.00e-161	561.00
IUUC-Gac-041888	Gasterosteus aculeatus	72.27	8.00e-127	445.00
IUUC-Gma-042798	Glycine max	39.51	5.00e-12	65.10
IUUC-Ggo-045027	Gorilla gorilla	97.77	2.00e-171	594.00
IUUC-Hsa-045665	Homo sapiens	97.77	3.00e-172	597.00
IUUC-Itr-049045	Ictidomys tridecemlineatus	97.13	1.00e-168	584.00
IUUC-Lch-049714	Latimeria chalumnae	87.16	2.00e-161	560.00
IUUC-Lpe-051490	Leersia perrieri	42.03	9.00e-12	63.90
IUUC-Loc-052161	Lepisosteus oculatus	81.96	3.00e-142	497.00
IUUC-Laf-054108	Loxodonta africana	95.60	9.00e-169	585.00
IUUC-Mcc-055562	Macaca mulatta	97.77	3.00e-172	597.00
IUUC-Meu-056709	Macropus eugenii	98.47	2.00e-173	600.00
IUUC-Mtr-058158	Medicago truncatula	43.42	3.00e-10	57.00
IUUC-Mla-059113	Melampsora laricipopulina	36.17	4.00e-05	42.00
IUUC-Mga-060104	Meleagris gallopavo	95.18	3.00e-116	410.00
IUUC-Mmr-061191	Microcebus murinus	97.77	3.00e-172	597.00
IUUC-Mdo-062711	Monodelphis domestica	93.17	2.00e-153	534.00
IUUC-Mmu-064255	Mus musculus	93.31	2.00e-157	547.00
IUUC-Mpu-066466	Mustela putorius furo	96.63	8.00e-165	572.00
IUUC-Mlu-067622	Myotis lucifugus	97.13	2.00e-170	590.00
IUUC-Nle-069253	Nomascus leucogenys	97.77	3.00e-172	597.00
IUUC-Opr-070511	Ochotona princeps	96.50	4.00e-170	589.00
IUUC-Ont-072177	Oreochromis niloticus	84.29	3.00e-129	454.00
IUUC-Ocu-074113	Oryctolagus cuniculus	97.13	1.00e-160	557.00
IUUC-Osa-086282	Oryza sativa	42.25	4.00e-12	65.50
IUUC-Ola-087057	Oryzias latipes	84.55	5.00e-124	436.00
IUUC-Oga-088346	Otolemur garnettii	97.77	2.00e-171	594.00
IUUC-Oar-089843	Ovis aries	97.55	3.00e-166	576.00
IUUC-Ptr-090486	Pan troglodytes	97.77	2.00e-171	594.00
IUUC-Pan-092667	Papio anubis	98.48	1.00e-158	551.00
IUUC-Psi-093469	Pelodiscus sinensis	96.93	1.00e-173	601.00
IUUC-Pma-094481	Petromyzon marinus	74.04	8.00e-90	322.00
IUUC-Ppa-095811	Physcomitrella patens	41.38	3.00e-10	59.30
IUUC-Pfo-097156	Poecilia formosa	79.39	8.00e-133	465.00
IUUC-Pab-097670	Pongo abelii	97.77	2.00e-171	594.00
IUUC-Pop-099100	Populus trichocarpa	37.65	1.00e-12	67.00
IUUC-Pca-100551	Procavia capensis	71.70	3.00e-111	394.00
IUUC-Ppe-102026	Prunus persica	36.46	7.00e-13	67.40
IUUC-Pva-102800	Pteropus vampyrus	97.77	2.00e-171	594.00
IUUC-Rno-105128	Rattus norvegicus	92.36	7.00e-160	555.00
IUUC-Sha-106747	Sarcophilus harrisii	99.08	1.00e-163	568.00
IUUC-Smo-109158	Selaginella moellendorffii	46.38	4.00e-11	62.40
IUUC-Sly-111012	Solanum lycopersicum	45.07	6.00e-13	67.80
IUUC-Stu-112047	Solanum tuberosum	45.07	1.00e-12	67.40
IUUC-Sar-113416	Sorex araneus	97.13	1.00e-170	591.00
IUUC-Sbi-114697	Sorghum bicolor	40.85	1.00e-10	60.10
IUUC-Ssc-115864	Sus scrofa	97.45	3.00e-171	593.00
IUUC-Tgu-116851	Taeniopygia guttata	96.88	4.00e-137	479.00
IUUC-Tru-117698	Takifugu rubripes	84.80	2.00e-124	437.00
IUUC-Tsy-119590	Tarsius syrichta	97.77	2.00e-171	594.00
IUUC-Tni-120170	Tetraodon nigroviridis	83.46	1.00e-128	451.00
IUUC-Tca-121851	Theobroma cacao	40.85	3.00e-11	62.00
IUUC-Tbe-127790	Tupaia belangeri	97.45	6.00e-171	592.00
IUUC-Ttr-129316	Tursiops truncatus	97.55	4.00e-175	606.00
IUUC-Vpa-130669	Vicugna pacos	97.85	2.00e-166	577.00
IUUC-Xtr-131912	Xenopus tropicalis	87.46	6.00e-145	506.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence