iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022183

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02031837

Gene Name

SKP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000013303.3	ENSCPOT00000013433.2	ENSCPOP00000011977.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	28.70	1.00e-30	130.00	IUUC-Cel-018410
E3 adaptor/Cullin RING/SCF/F-box	90.33	0.00e+00	790.00	IUUC-Hsa-046512
E3 adaptor/Cullin RING/SCF/F-box	56.37	5.00e-126	448.00	IUUC-Ots-000025

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

FHRKHLQEIP DQSSNVTTSF TWGWDSNKTS ELLSGMGVSA LEKEEVDSEN IPQELLPNVG 60
HPQSPPRKRL KSKGNDKDFV IIRRPKLNRE NFPGVSWDSL PDELLLGIFS CLCLPELLRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCACAGGA AGCACCTCCA GGAGATTCCA GACCAGAGTA GCAACGTTAC CACCAGCTTC 60
ACCTGGGGAT GGGATTCCAA TAAGACTTCT GAACTGTTGT CAGGCATGGG GGTCTCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051726--P:regulation of cell cycle
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002197	Ailuropoda melanoleuca	91.04	0.00e+00	772.00
IUUC-Atr-002711	Amborella trichopoda	21.92	8.00e-09	56.20
IUUC-Apl-003453	Anas platyrhynchos	67.87	3.00e-119	421.00
IUUC-Aca-005185	Anolis carolinensis	62.59	9.00e-141	493.00
IUUC-Ame-010665	Astyanax mexicanus	47.26	1.00e-91	329.00
IUUC-Bta-013450	Bos taurus	89.39	0.00e+00	791.00
IUUC-Bra-016626	Brassica rapa	23.55	6.00e-11	63.20
IUUC-Cel-018410	Caenorhabditis elegans	28.40	5.00e-28	118.00
IUUC-Cja-019834	Callithrix jacchus	91.27	0.00e+00	795.00
IUUC-Cfa-020401	Canis familiaris	91.51	0.00e+00	801.00
IUUC-Csa-023418	Chlorocebus sabaeus	90.33	0.00e+00	788.00
IUUC-Cho-024412	Choloepus hoffmanni	87.57	0.00e+00	630.00
IUUC-Cin-025248	Ciona intestinalis	32.01	1.00e-41	163.00
IUUC-Csv-026189	Ciona savignyi	29.89	9.00e-37	147.00
IUUC-Cme-027297	Cyanidioschyzon merolae	37.14	2.00e-06	46.60
IUUC-Dre-028032	Danio rerio	48.66	3.00e-104	372.00
IUUC-Dno-029222	Dasypus novemcinctus	89.39	0.00e+00	786.00
IUUC-Dor-030505	Dipodomys ordii	89.55	1.00e-178	619.00
IUUC-Dme-031972	Drosophila melanogaster	33.70	5.00e-52	198.00
IUUC-Ete-032234	Echinops telfairi	83.70	8.00e-118	416.00
IUUC-Eca-033944	Equus caballus	91.98	0.00e+00	805.00
IUUC-Eeu-035008	Erinaceus europaeus	84.23	5.00e-121	427.00
IUUC-Fca-035412	Felis catus	91.04	0.00e+00	795.00
IUUC-Fal-037337	Ficedula albicollis	63.03	1.00e-136	479.00
IUUC-Gmo-038934	Gadus morhua	43.58	2.00e-41	163.00
IUUC-Gga-041152	Gallus gallus	66.67	2.00e-157	548.00
IUUC-Gac-041819	Gasterosteus aculeatus	45.05	4.00e-76	278.00
IUUC-Ggo-045479	Gorilla gorilla	89.83	0.00e+00	656.00
IUUC-Hsa-046512	Homo sapiens	90.33	0.00e+00	790.00
IUUC-Itr-048515	Ictidomys tridecemlineatus	92.38	0.00e+00	775.00
IUUC-Lch-050115	Latimeria chalumnae	58.47	1.00e-139	489.00
IUUC-Loc-052554	Lepisosteus oculatus	49.41	4.00e-105	374.00
IUUC-Laf-053563	Loxodonta africana	89.86	0.00e+00	748.00
IUUC-Mcc-055143	Macaca mulatta	90.33	0.00e+00	787.00
IUUC-Meu-056593	Macropus eugenii	56.40	2.00e-104	372.00
IUUC-Mga-060084	Meleagris gallopavo	59.77	7.00e-83	300.00
IUUC-Mmr-060660	Microcebus murinus	92.69	0.00e+00	813.00
IUUC-Mdo-062363	Monodelphis domestica	70.38	1.00e-161	562.00
IUUC-Mmu-063287	Mus musculus	85.85	0.00e+00	751.00
IUUC-Mpu-065791	Mustela putorius furo	90.57	0.00e+00	796.00
IUUC-Mlu-067714	Myotis lucifugus	88.99	0.00e+00	753.00
IUUC-Nle-069823	Nomascus leucogenys	90.80	0.00e+00	793.00
IUUC-Opr-071046	Ochotona princeps	75.39	2.00e-109	389.00
IUUC-Ont-071820	Oreochromis niloticus	46.61	3.00e-68	252.00
IUUC-Ocu-074868	Oryctolagus cuniculus	92.69	0.00e+00	810.00
IUUC-Ola-086608	Oryzias latipes	47.40	3.00e-75	275.00
IUUC-Oga-089044	Otolemur garnettii	90.57	0.00e+00	795.00
IUUC-Oar-089650	Ovis aries	89.62	0.00e+00	790.00
IUUC-Ptr-090743	Pan troglodytes	90.33	0.00e+00	789.00
IUUC-Pan-092501	Papio anubis	90.33	0.00e+00	790.00
IUUC-Psi-094032	Pelodiscus sinensis	65.88	2.00e-158	551.00
IUUC-Pfo-097279	Poecilia formosa	46.02	2.00e-63	236.00
IUUC-Pab-097821	Pongo abelii	90.68	0.00e+00	659.00
IUUC-Pca-100100	Procavia capensis	90.11	3.00e-179	620.00
IUUC-Pva-103181	Pteropus vampyrus	90.96	0.00e+00	635.00
IUUC-Rno-105091	Rattus norvegicus	87.91	0.00e+00	761.00
IUUC-Sha-107226	Sarcophilus harrisii	71.09	5.00e-167	580.00
IUUC-Ssc-115665	Sus scrofa	91.98	0.00e+00	806.00
IUUC-Tgu-116982	Taeniopygia guttata	62.41	7.00e-134	470.00
IUUC-Tru-118276	Takifugu rubripes	45.77	2.00e-71	263.00
IUUC-Tsy-119074	Tarsius syrichta	91.53	0.00e+00	666.00
IUUC-Tni-120702	Tetraodon nigroviridis	47.55	1.00e-49	189.00
IUUC-Tbe-127990	Tupaia belangeri	91.95	3.00e-162	564.00
IUUC-Ttr-128661	Tursiops truncatus	77.69	1.00e-112	399.00
IUUC-Xtr-132166	Xenopus tropicalis	56.74	7.00e-128	450.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence