iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034401

UUCD1 version

UUC-EqC-00726

Ensembl Protein ID

ENSECAP00000011150.1

UniProt Accession

F7BIV4; F7BIV4_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRAF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000013192.1	ENSECAT00000013996.1	ENSECAP00000011150.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	90.10	0.00e+00	945.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MAAASVTPPG SLDLLQPGFS KTLLGTKLED KYLCSACKNV LRRPFQAQCG HRYCSYCLTS 60
ILSSGPQNCA ACVHEGIYEE GISILESSSA FPDNAARREV ESLPAVCPSD GCTWKGTLKE 120

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Nucleotide Sequence
(Fasta)

GTTCACGGGG GTCGCGGCTC TCATGGCTGC AGCTAGTGTG ACTCCTCCTG GCTCCCTAGA 60
TTTGCTGCAG CCCGGCTTCT CAAAGACCCT TCTGGGGACC AAGCTGGAGG ACAAGTACCT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	90.06	0.00e+00	964.00
IUUC-Apl-004202	Anas platyrhynchos	73.55	0.00e+00	824.00
IUUC-Aca-005029	Anolis carolinensis	57.51	1.00e-145	509.00
IUUC-Ame-011841	Astyanax mexicanus	55.77	0.00e+00	653.00
IUUC-Bta-013180	Bos taurus	88.67	0.00e+00	921.00
IUUC-Cja-019813	Callithrix jacchus	90.10	0.00e+00	944.00
IUUC-Cfa-021205	Canis familiaris	93.66	0.00e+00	956.00
IUUC-Cpo-021346	Cavia porcellus	86.05	0.00e+00	912.00
IUUC-Csa-023809	Chlorocebus sabaeus	89.71	0.00e+00	830.00
IUUC-Dre-027669	Danio rerio	57.34	1.00e-175	609.00
IUUC-Dno-029458	Dasypus novemcinctus	82.85	0.00e+00	888.00
IUUC-Dor-030338	Dipodomys ordii	84.75	0.00e+00	830.00
IUUC-Eeu-034668	Erinaceus europaeus	95.39	2.00e-84	305.00
IUUC-Fca-036057	Felis catus	90.63	0.00e+00	976.00
IUUC-Fal-037560	Ficedula albicollis	72.83	0.00e+00	736.00
IUUC-Gmo-038964	Gadus morhua	62.33	0.00e+00	666.00
IUUC-Gga-040425	Gallus gallus	74.15	0.00e+00	825.00
IUUC-Gac-041908	Gasterosteus aculeatus	63.19	0.00e+00	676.00
IUUC-Ggo-044606	Gorilla gorilla	83.17	0.00e+00	855.00
IUUC-Hsa-046952	Homo sapiens	90.10	0.00e+00	945.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	74.33	0.00e+00	754.00
IUUC-Lch-049571	Latimeria chalumnae	59.01	0.00e+00	703.00
IUUC-Loc-051973	Lepisosteus oculatus	62.40	0.00e+00	636.00
IUUC-Laf-053815	Loxodonta africana	83.92	0.00e+00	861.00
IUUC-Mcc-054888	Macaca mulatta	90.30	0.00e+00	944.00
IUUC-Meu-056547	Macropus eugenii	72.17	0.00e+00	652.00
IUUC-Mga-059819	Meleagris gallopavo	74.05	0.00e+00	782.00
IUUC-Mdo-062570	Monodelphis domestica	82.18	0.00e+00	863.00
IUUC-Mmu-063133	Mus musculus	85.35	0.00e+00	875.00
IUUC-Mpu-065802	Mustela putorius furo	90.04	0.00e+00	954.00
IUUC-Nle-070155	Nomascus leucogenys	90.69	0.00e+00	949.00
IUUC-Opr-070856	Ochotona princeps	80.08	9.00e-108	383.00
IUUC-Ont-071930	Oreochromis niloticus	64.69	0.00e+00	715.00
IUUC-Ola-087397	Oryzias latipes	60.71	0.00e+00	687.00
IUUC-Oga-088109	Otolemur garnettii	89.70	0.00e+00	942.00
IUUC-Oar-090310	Ovis aries	78.89	0.00e+00	819.00
IUUC-Ptr-090643	Pan troglodytes	90.69	0.00e+00	948.00
IUUC-Pan-091933	Papio anubis	90.59	0.00e+00	946.00
IUUC-Psi-093681	Pelodiscus sinensis	74.51	0.00e+00	798.00
IUUC-Pfo-096148	Poecilia formosa	60.71	0.00e+00	694.00
IUUC-Pab-098631	Pongo abelii	90.69	0.00e+00	950.00
IUUC-Pca-100582	Procavia capensis	65.98	1.00e-83	303.00
IUUC-Pva-102396	Pteropus vampyrus	75.45	0.00e+00	756.00
IUUC-Rno-106120	Rattus norvegicus	82.84	0.00e+00	863.00
IUUC-Sha-106493	Sarcophilus harrisii	81.78	0.00e+00	879.00
IUUC-Sar-113570	Sorex araneus	93.37	1.00e-99	356.00
IUUC-Ssc-115843	Sus scrofa	87.74	0.00e+00	940.00
IUUC-Tgu-117144	Taeniopygia guttata	69.14	0.00e+00	697.00
IUUC-Tru-117853	Takifugu rubripes	61.52	0.00e+00	688.00
IUUC-Tni-120256	Tetraodon nigroviridis	65.35	0.00e+00	721.00
IUUC-Tbe-127943	Tupaia belangeri	64.78	2.00e-100	358.00
IUUC-Ttr-129246	Tursiops truncatus	90.10	0.00e+00	927.00
IUUC-Xtr-132279	Xenopus tropicalis	60.71	5.00e-176	610.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence