iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000011278.5	ENSGALT00000018402.5	ENSGALP00000018380.5
ENSGALG00000011278.5	ENSGALT00000059415.1	ENSGALP00000053796.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	91.72	0.00e+00	1376.00	IUUC-Hsa-046970

Active Site

Position(s)	Description	Evidence
546	Proton donor/acceptor	{ECO:0000256\|PIRSR:PIRSR003048-1}

Organism

Gallus gallus

Protein Sequence
(Fasta)

MAEAGGGAAA VAAGGGGPQQ GSPAAGGVAA AATGGPARSA AESPGGPGSA RTAGKKAQLR 60
AAPRAKKLEK LGVYSACKAE ESCKCNGWKN PNPPPTPPRA DLQQAVVSLT EPCRSCSHTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGCGGCGG CGCGGCGAAG GGGAGGGTCT AGGGCCGGGC GCACCGCGCC GGCCGGCCGG 60
ACGGGCGGCT GCCGCCGCGC CGCGGGCATG GCGGAGGCGG GCGGCGGGGC CGCGGCCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR016376--GCN5/PCAF
IPR000182--GNAT_dom
IPR009464--PCAF_N

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51186--GNAT

Pfam

PF00583--Acetyltransf_1
PF00439--Bromodomain
PF06466--PCAF_N

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO

Gene Ontology

GO:0031672--C:A band
GO:0042641--C:actomyosin
GO:0005671--C:Ada2/Gcn5/Ada3 transcription activator complex
GO:0031674--C:I band
GO:0000776--C:kinetochore
GO:0003682--F:chromatin binding
GO:0004861--F:cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0004402--F:histone acetyltransferase activity
GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0032869--P:cellular response to insulin stimulus
GO:0006338--P:chromatin remodeling
GO:0043970--P:histone H3-K9 acetylation
GO:0018076--P:N-terminal peptidyl-lysine acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0035948--P:positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
GO:0010835--P:regulation of protein ADP-ribosylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001599	Ailuropoda melanoleuca	89.73	0.00e+00	1265.00
IUUC-Atr-003130	Amborella trichopoda	43.08	7.00e-87	314.00
IUUC-Apl-004026	Anas platyrhynchos	98.91	0.00e+00	1387.00
IUUC-Aly-006486	Arabidopsis lyrata	43.21	3.00e-76	278.00
IUUC-Ath-006763	Arabidopsis thaliana	43.36	1.00e-76	280.00
IUUC-Ago-007819	Ashbya gossypii	49.29	2.00e-89	322.00
IUUC-Acl-008194	Aspergillus clavatus	44.60	2.00e-80	292.00
IUUC-Afl-008546	Aspergillus flavus	44.32	1.00e-80	293.00
IUUC-Afu-009124	Aspergillus fumigatus	45.17	8.00e-82	296.00
IUUC-Ani-009432	Aspergillus nidulans	43.08	1.00e-75	276.00
IUUC-Ang-009824	Aspergillus niger	44.89	3.00e-81	295.00
IUUC-Aor-010076	Aspergillus oryzae	43.45	9.00e-79	286.00
IUUC-Bgr-012003	Blumeria graminis	41.82	5.00e-75	274.00
IUUC-Bta-012381	Bos taurus	89.11	0.00e+00	1301.00
IUUC-Bci-013974	Botrytis cinerea	44.64	1.00e-81	296.00
IUUC-Bdi-015016	Brachypodium distachyon	43.41	6.00e-83	301.00
IUUC-Cel-018633	Caenorhabditis elegans	46.92	1.00e-84	307.00
IUUC-Cja-019375	Callithrix jacchus	90.87	0.00e+00	1245.00
IUUC-Cfa-020400	Canis familiaris	85.81	0.00e+00	1174.00
IUUC-Cpo-021686	Cavia porcellus	91.79	0.00e+00	1321.00
IUUC-Cre-023019	Chlamydomonas reinhardtii	53.80	4.00e-52	198.00
IUUC-Csa-024252	Chlorocebus sabaeus	91.70	0.00e+00	1234.00
IUUC-Cho-024635	Choloepus hoffmanni	87.28	0.00e+00	893.00
IUUC-Cgl-026660	Colletotrichum gloeosporioides	43.75	2.00e-75	276.00
IUUC-Cne-027050	Cryptococcus neoformans	43.49	3.00e-70	259.00
IUUC-Dre-027468	Danio rerio	84.49	0.00e+00	1250.00
IUUC-Dno-029306	Dasypus novemcinctus	82.61	0.00e+00	1142.00
IUUC-Dor-030465	Dipodomys ordii	78.92	1.00e-165	576.00
IUUC-Dse-031386	Dothistroma septosporum	40.32	8.00e-70	257.00
IUUC-Eca-034212	Equus caballus	91.79	0.00e+00	1290.00
IUUC-Eeu-034605	Erinaceus europaeus	63.80	2.00e-180	625.00
IUUC-Fca-035972	Felis catus	91.26	0.00e+00	1229.00
IUUC-Fal-037223	Ficedula albicollis	97.26	0.00e+00	1401.00
IUUC-Fox-037874	Fusarium oxysporum	44.13	3.00e-76	278.00
IUUC-Fso-038286	Fusarium solani	44.32	2.00e-76	279.00
IUUC-Gmo-039102	Gadus morhua	82.90	0.00e+00	1238.00
IUUC-Ggr-039925	Gaeumannomyces graminis	45.71	4.00e-80	291.00
IUUC-Gac-041887	Gasterosteus aculeatus	84.19	0.00e+00	1209.00
IUUC-Gma-043540	Glycine max	43.42	1.00e-86	313.00
IUUC-Ggo-044607	Gorilla gorilla	91.70	0.00e+00	1372.00
IUUC-Hsa-046970	Homo sapiens	91.70	0.00e+00	1373.00
IUUC-Hvu-047105	Hordeum vulgare	46.00	2.00e-51	195.00
IUUC-Kpa-049146	Komagataella pastoris	44.20	2.00e-83	303.00
IUUC-Lch-049478	Latimeria chalumnae	91.03	0.00e+00	1361.00
IUUC-Lpe-051678	Leersia perrieri	43.51	2.00e-75	276.00
IUUC-Loc-052255	Lepisosteus oculatus	88.21	0.00e+00	1340.00
IUUC-Laf-054575	Loxodonta africana	91.33	0.00e+00	1309.00
IUUC-Mcc-055161	Macaca mulatta	91.20	0.00e+00	1323.00
IUUC-Mor-057026	Magnaporthe oryzae	44.66	5.00e-81	294.00
IUUC-Mpo-057590	Magnaporthe poae	44.41	2.00e-79	289.00
IUUC-Mtr-057835	Medicago truncatula	45.92	5.00e-80	291.00
IUUC-Mla-058950	Melampsora laricipopulina	44.99	2.00e-76	278.00
IUUC-Mvi-060295	Microbotryum violaceum	46.45	3.00e-77	283.00
IUUC-Mmr-060643	Microcebus murinus	89.24	0.00e+00	1302.00
IUUC-Mdo-062732	Monodelphis domestica	93.42	0.00e+00	1401.00
IUUC-Mmu-064125	Mus musculus	88.67	0.00e+00	1288.00
IUUC-Mpu-066371	Mustela putorius furo	91.56	0.00e+00	1232.00
IUUC-Mlu-067447	Myotis lucifugus	89.60	0.00e+00	1272.00
IUUC-Nfi-068373	Neosartorya fischeri	45.17	2.00e-82	299.00
IUUC-Ncr-068652	Neurospora crassa	43.47	3.00e-76	278.00
IUUC-Nle-069659	Nomascus leucogenys	91.70	0.00e+00	1372.00
IUUC-Ont-071244	Oreochromis niloticus	84.81	0.00e+00	1245.00
IUUC-Oan-072794	Ornithorhynchus anatinus	96.00	0.00e+00	1284.00
IUUC-Ocu-074701	Oryctolagus cuniculus	89.69	0.00e+00	1238.00
IUUC-Oba-075479	Oryza barthii	41.90	2.00e-56	213.00
IUUC-Ogl-076970	Oryza glaberrima	42.55	3.00e-78	285.00
IUUC-Oin-079610	Oryza indica	41.90	3.00e-56	212.00
IUUC-Oni-083016	Oryza nivara	42.26	5.00e-77	281.00
IUUC-Opu-083976	Oryza punctata	42.97	7.00e-77	281.00
IUUC-Osa-085814	Oryza sativa	42.55	3.00e-78	285.00
IUUC-Ola-087071	Oryzias latipes	83.25	0.00e+00	1229.00
IUUC-Olu-087711	Ostreococcus lucimarinus	42.03	8.00e-78	283.00
IUUC-Oga-089043	Otolemur garnettii	92.09	0.00e+00	1343.00
IUUC-Oar-089893	Ovis aries	84.81	0.00e+00	1200.00
IUUC-Ptr-090629	Pan troglodytes	91.57	0.00e+00	1372.00
IUUC-Pan-092305	Papio anubis	91.33	0.00e+00	1365.00
IUUC-Psi-093574	Pelodiscus sinensis	94.26	0.00e+00	1368.00
IUUC-Pma-094160	Petromyzon marinus	76.71	0.00e+00	1128.00
IUUC-Ppa-095410	Physcomitrella patens	43.29	6.00e-79	288.00
IUUC-Pfo-097043	Poecilia formosa	85.11	0.00e+00	1245.00
IUUC-Pab-098748	Pongo abelii	87.58	0.00e+00	744.00
IUUC-Pca-100223	Procavia capensis	90.03	0.00e+00	1290.00
IUUC-Ppe-101832	Prunus persica	45.78	6.00e-87	314.00
IUUC-Pva-102122	Pteropus vampyrus	91.83	0.00e+00	1339.00
IUUC-Pte-104228	Pyrenophora teres	43.63	3.00e-82	298.00
IUUC-Pyt-104702	Pyrenophora triticirepentis	44.00	3.00e-82	298.00
IUUC-Sce-106432	Saccharomyces cerevisiae	47.90	6.00e-86	310.00
IUUC-Sha-107338	Sarcophilus harrisii	94.35	0.00e+00	1261.00
IUUC-Spo-108273	Schizosaccharomyces pombe	47.89	2.00e-93	335.00
IUUC-Ssl-108545	Sclerotinia sclerotiorum	44.35	3.00e-79	288.00
IUUC-Smo-109385	Selaginella moellendorffii	43.15	9.00e-79	287.00
IUUC-Sit-110222	Setaria italica	43.35	4.00e-79	288.00
IUUC-Sly-111498	Solanum lycopersicum	48.36	8.00e-54	204.00
IUUC-Sar-113574	Sorex araneus	91.24	0.00e+00	1276.00
IUUC-Sbi-114471	Sorghum bicolor	44.41	2.00e-81	296.00
IUUC-Sre-114915	Sporisorium reilianum	42.90	1.00e-82	300.00
IUUC-Ssc-116097	Sus scrofa	90.75	0.00e+00	1210.00
IUUC-Tgu-116699	Taeniopygia guttata	97.54	0.00e+00	1383.00
IUUC-Tru-118001	Takifugu rubripes	83.07	0.00e+00	1205.00
IUUC-Tsy-118910	Tarsius syrichta	77.19	0.00e+00	790.00
IUUC-Tni-119684	Tetraodon nigroviridis	84.08	0.00e+00	1221.00
IUUC-Tca-121066	Theobroma cacao	43.21	1.00e-84	307.00
IUUC-Tre-122112	Trichoderma reesei	44.32	2.00e-78	286.00
IUUC-Tvi-122355	Trichoderma virens	44.32	3.00e-78	285.00
IUUC-Tae-123931	Triticum aestivum	42.18	2.00e-76	279.00
IUUC-Tur-126587	Triticum urartu	44.02	2.00e-76	279.00
IUUC-Tme-126963	Tuber melanosporum	45.40	1.00e-85	309.00
IUUC-Tbe-127304	Tupaia belangeri	78.80	0.00e+00	1107.00
IUUC-Ttr-128536	Tursiops truncatus	90.83	0.00e+00	1276.00
IUUC-Uma-129538	Ustilago maydis	42.63	1.00e-81	297.00
IUUC-Vda-129860	Verticillium dahliae	43.91	1.00e-80	293.00
IUUC-Vpa-130239	Vicugna pacos	72.66	4.00e-152	531.00
IUUC-Vvi-130897	Vitis vinifera	44.54	8.00e-87	314.00
IUUC-Xtr-132300	Xenopus tropicalis	89.72	0.00e+00	1307.00
IUUC-Xma-134105	Xiphophorus maculatus	82.23	0.00e+00	1231.00
IUUC-Yli-134345	Yarrowia lipolytica	49.00	5.00e-88	318.00
IUUC-Zma-135384	Zea mays	44.35	2.00e-78	285.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence