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Tag Content
iUUCD ID IUUC-Dre-028199
Ensembl Protein ID ENSDARP00000138677.1
UniProt Accession A0A0R4IS91; A0A0R4IS91_DANRE
Genbank Protein ID ENSDARP00000138677
Protein Name Vav 3 guanine nucleotide exchange factor b
Genbank Nucleotide ID BX510321
Gene Name vav3b
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000075962.5 ENSDART00000110059.4 ENSDARP00000099666.3
ENSDARG00000075962.5 ENSDART00000142828.1 ENSDARP00000122702.1
ENSDARG00000075962.5 ENSDART00000167782.1 ENSDARP00000138677.1
ENSDARG00000075962.5 ENSDART00000153480.2 ENSDARP00000128776.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 3.90e-16 59.7 802 851
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 8    vlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + yd+++ ++ eL+l+ Gd v++    +  +gW+kg  e +g+ G fP+ +ve+
   Q: 802  ARYDFSSRDTRELSLQVGDLVKIY--IKCTNGWWKG--EVNGRVGWFPSTYVEE 851
           56*********************7..77789*****..9*************86 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MEYWRQCSLW LINCKVLPRN HRVTADSAQV FDLAQTLRDG VLLCQLLNNL RPDTINLKEI 60
NLRPQMSQFL CLKNIRTFLS ACCEEFGMKK SDLFEAFDLF DVRDFGKVID TLSKLSYTPV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028199|UBD,SH3|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GATCAACCAC GCAACGTAAT CAATACCTAA TTAATATTCA TAAGACTTCG CCGAAGATCA 60
GAGGCACGTC GCACGACTCA TTTATTATAA ACCGTTGCCA TAGTAGAATA CGTAACTCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028199|UBD,SH3|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc
Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain
IPR003096--SM22_calponin
PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2
Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2
PRINTS

PR00452--SH3DOMAIN
PR00888--SM22CALPONIN
SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3
Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001362 Ailuropoda melanoleuca 67.20 0.00e+00 1066.00
IUUC-Apl-003734 Anas platyrhynchos 66.46 0.00e+00 991.00
IUUC-Aca-004477 Anolis carolinensis 67.58 0.00e+00 1102.00
IUUC-Ame-011279 Astyanax mexicanus 63.89 0.00e+00 1025.00
IUUC-Bta-012722 Bos taurus 67.05 0.00e+00 1070.00
IUUC-Cja-018941 Callithrix jacchus 67.02 0.00e+00 1062.00
IUUC-Cfa-020266 Canis familiaris 65.22 0.00e+00 910.00
IUUC-Cpo-021966 Cavia porcellus 63.70 0.00e+00 894.00
IUUC-Csa-023892 Chlorocebus sabaeus 65.55 0.00e+00 957.00
IUUC-Dno-029474 Dasypus novemcinctus 67.01 0.00e+00 1068.00
IUUC-Eca-033961 Equus caballus 64.97 0.00e+00 936.00
IUUC-Eeu-034719 Erinaceus europaeus 50.45 2.00e-139 490.00
IUUC-Fca-036572 Felis catus 66.67 0.00e+00 1035.00
IUUC-Fal-036802 Ficedula albicollis 68.95 0.00e+00 1152.00
IUUC-Gmo-039409 Gadus morhua 68.74 0.00e+00 1130.00
IUUC-Gga-040884 Gallus gallus 66.59 0.00e+00 1095.00
IUUC-Gac-041395 Gasterosteus aculeatus 70.92 0.00e+00 1199.00
IUUC-Ggo-044460 Gorilla gorilla 63.06 0.00e+00 879.00
IUUC-Hsa-046099 Homo sapiens 68.22 0.00e+00 1119.00
IUUC-Hvu-047839 Hordeum vulgare 45.83 9.00e-09 53.10
IUUC-Itr-048144 Ictidomys tridecemlineatus 65.25 0.00e+00 945.00
IUUC-Lch-049650 Latimeria chalumnae 60.52 5.00e-79 286.00
IUUC-Loc-052487 Lepisosteus oculatus 69.27 0.00e+00 1147.00
IUUC-Laf-054564 Loxodonta africana 67.09 0.00e+00 1066.00
IUUC-Mcc-054622 Macaca mulatta 68.00 0.00e+00 1119.00
IUUC-Meu-056680 Macropus eugenii 62.49 0.00e+00 1001.00
IUUC-Mga-060013 Meleagris gallopavo 66.21 0.00e+00 1081.00
IUUC-Mmr-061251 Microcebus murinus 66.07 0.00e+00 1118.00
IUUC-Mdo-061875 Monodelphis domestica 66.94 0.00e+00 1094.00
IUUC-Mmu-063735 Mus musculus 66.48 0.00e+00 1098.00
IUUC-Mpu-065856 Mustela putorius furo 66.86 0.00e+00 1064.00
IUUC-Mlu-068108 Myotis lucifugus 66.82 0.00e+00 1053.00
IUUC-Nle-069863 Nomascus leucogenys 66.86 0.00e+00 1084.00
IUUC-Opr-070372 Ochotona princeps 59.31 0.00e+00 691.00
IUUC-Ont-072249 Oreochromis niloticus 70.37 0.00e+00 1249.00
IUUC-Ocu-074194 Oryctolagus cuniculus 66.48 0.00e+00 1084.00
IUUC-Ola-086336 Oryzias latipes 69.52 0.00e+00 1178.00
IUUC-Oga-089104 Otolemur garnettii 54.16 0.00e+00 873.00
IUUC-Oar-089272 Ovis aries 66.97 0.00e+00 1097.00
IUUC-Ptr-090652 Pan troglodytes 65.37 0.00e+00 1058.00
IUUC-Pan-092550 Papio anubis 65.99 0.00e+00 962.00
IUUC-Psi-093784 Pelodiscus sinensis 65.80 0.00e+00 981.00
IUUC-Ppa-095161 Physcomitrella patens 40.00 1.00e-10 61.20
IUUC-Pfo-097308 Poecilia formosa 72.81 0.00e+00 1257.00
IUUC-Pab-098698 Pongo abelii 65.17 0.00e+00 1057.00
IUUC-Pva-102262 Pteropus vampyrus 66.74 0.00e+00 1036.00
IUUC-Rno-105421 Rattus norvegicus 66.82 0.00e+00 1109.00
IUUC-Sha-107325 Sarcophilus harrisii 67.09 0.00e+00 1096.00
IUUC-Sar-113456 Sorex araneus 62.60 0.00e+00 1011.00
IUUC-Ssc-115338 Sus scrofa 52.57 0.00e+00 786.00
IUUC-Tgu-116595 Taeniopygia guttata 65.85 0.00e+00 1056.00
IUUC-Tru-117884 Takifugu rubripes 67.05 0.00e+00 1202.00
IUUC-Tsy-119429 Tarsius syrichta 61.07 0.00e+00 869.00
IUUC-Tni-119951 Tetraodon nigroviridis 68.42 0.00e+00 1127.00
IUUC-Tbe-127995 Tupaia belangeri 62.37 3.00e-130 459.00
IUUC-Ttr-128281 Tursiops truncatus 67.28 0.00e+00 1067.00
IUUC-Xtr-132427 Xenopus tropicalis 60.48 0.00e+00 1036.00
Created Date 25-Jun-2017

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