iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003961

Ensembl Protein ID

ENSAPLP00000005862.1

UniProt Accession

U3IF40; U3IF40_ANAPL

Genbank Protein ID

ENSAPLP00000005862

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01065751

Gene Name

SH3RF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000006243.1	ENSAPLT00000006497.1	ENSAPLP00000005862.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.10e-08	32.6	35	76
UBD/SH3	2.00e-48	161.9	466	521

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +     ss++e rCP Cr
   Q: 35   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VSSRNELRCPECR 76
           **********9**************9777....89**********8 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           + +++y+y++ ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+v+ +
   Q: 466  VYIAIYPYTPRKEDELELRKGEMFLVF-ERC-QDGWFKGTSMHTSKIGVFPGNYVAPV 521
           5789**********************9.555.569********************988 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

SLGALKTPEF CEDCFFRLSD TKKMDESALL DLLECPVCLE RLDASAKVLP CQHTFCKRCL 60
LGIVSSRNEL RCPECRTLVD CSVDELPSNI LLVRLLDGIK QRPRKPGTGG GTGGTNALRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCTTGGAG CGCTCAAAAC ACCCGAATTC TGTGAAGATT GTTTTTTTCG GCTGAGCGAT 60
ACGAAGAAAA TGGATGAATC GGCTCTGCTG GATCTGCTGG AGTGCCCGGT GTGCCTCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	79.95	0.00e+00	1155.00
IUUC-Aca-004386	Anolis carolinensis	82.74	0.00e+00	1276.00
IUUC-Ame-010659	Astyanax mexicanus	60.26	0.00e+00	913.00
IUUC-Bta-012563	Bos taurus	62.53	2.00e-118	419.00
IUUC-Cja-019730	Callithrix jacchus	77.98	0.00e+00	1140.00
IUUC-Cfa-020992	Canis familiaris	79.02	0.00e+00	1184.00
IUUC-Cpo-021304	Cavia porcellus	78.88	0.00e+00	1211.00
IUUC-Csa-023925	Chlorocebus sabaeus	78.38	0.00e+00	1155.00
IUUC-Cho-024630	Choloepus hoffmanni	73.48	0.00e+00	771.00
IUUC-Cin-025274	Ciona intestinalis	47.45	1.00e-72	266.00
IUUC-Csv-026136	Ciona savignyi	43.54	4.00e-72	264.00
IUUC-Cme-027278	Cyanidioschyzon merolae	42.55	3.00e-08	53.50
IUUC-Dre-028290	Danio rerio	62.29	0.00e+00	934.00
IUUC-Dno-029083	Dasypus novemcinctus	82.32	0.00e+00	909.00
IUUC-Dor-030388	Dipodomys ordii	85.11	5.00e-166	577.00
IUUC-Dme-032207	Drosophila melanogaster	46.99	9.00e-66	244.00
IUUC-Ete-032809	Echinops telfairi	70.61	0.00e+00	746.00
IUUC-Eca-034185	Equus caballus	79.13	0.00e+00	992.00
IUUC-Eeu-034816	Erinaceus europaeus	69.81	0.00e+00	985.00
IUUC-Fca-036439	Felis catus	77.58	0.00e+00	1204.00
IUUC-Fal-037074	Ficedula albicollis	93.59	0.00e+00	1356.00
IUUC-Gmo-039443	Gadus morhua	60.32	2.00e-117	416.00
IUUC-Ggr-040119	Gaeumannomyces graminis	41.38	5.00e-12	66.60
IUUC-Gga-040749	Gallus gallus	94.39	0.00e+00	1340.00
IUUC-Gac-041420	Gasterosteus aculeatus	73.77	1.00e-147	516.00
IUUC-Ggo-045215	Gorilla gorilla	79.03	0.00e+00	1180.00
IUUC-Hsa-046315	Homo sapiens	79.73	0.00e+00	1172.00
IUUC-Itr-048265	Ictidomys tridecemlineatus	73.82	7.00e-132	463.00
IUUC-Kpa-049247	Komagataella pastoris	41.82	5.00e-10	58.50
IUUC-Lch-049453	Latimeria chalumnae	74.73	0.00e+00	932.00
IUUC-Loc-052248	Lepisosteus oculatus	38.26	3.00e-78	286.00
IUUC-Laf-053651	Loxodonta africana	78.78	0.00e+00	1160.00
IUUC-Mcc-054688	Macaca mulatta	78.43	0.00e+00	1175.00
IUUC-Meu-056291	Macropus eugenii	62.01	0.00e+00	774.00
IUUC-Mor-056932	Magnaporthe oryzae	40.00	3.00e-12	67.40
IUUC-Mpo-057322	Magnaporthe poae	41.38	5.00e-12	67.00
IUUC-Mga-059944	Meleagris gallopavo	93.36	0.00e+00	1380.00
IUUC-Mmr-061553	Microcebus murinus	77.54	0.00e+00	1103.00
IUUC-Mdo-062313	Monodelphis domestica	77.30	0.00e+00	1174.00
IUUC-Mmu-063516	Mus musculus	79.15	0.00e+00	1216.00
IUUC-Mpu-066064	Mustela putorius furo	78.64	0.00e+00	1160.00
IUUC-Mlu-067312	Myotis lucifugus	76.34	0.00e+00	1115.00
IUUC-Nle-069035	Nomascus leucogenys	78.80	0.00e+00	1174.00
IUUC-Opr-070690	Ochotona princeps	74.56	4.00e-165	574.00
IUUC-Ont-071484	Oreochromis niloticus	61.00	0.00e+00	886.00
IUUC-Oan-073305	Ornithorhynchus anatinus	81.00	0.00e+00	1212.00
IUUC-Ocu-074936	Oryctolagus cuniculus	77.68	0.00e+00	1171.00
IUUC-Ola-086675	Oryzias latipes	62.58	6.00e-179	620.00
IUUC-Oga-087933	Otolemur garnettii	73.75	0.00e+00	933.00
IUUC-Oar-090408	Ovis aries	62.00	6.00e-111	394.00
IUUC-Ptr-090865	Pan troglodytes	78.94	0.00e+00	1179.00
IUUC-Pan-092362	Papio anubis	78.38	0.00e+00	1154.00
IUUC-Psi-093876	Pelodiscus sinensis	86.99	0.00e+00	1292.00
IUUC-Pfo-097116	Poecilia formosa	61.34	0.00e+00	906.00
IUUC-Pab-098127	Pongo abelii	78.94	0.00e+00	1177.00
IUUC-Pca-100485	Procavia capensis	80.39	0.00e+00	876.00
IUUC-Pva-102661	Pteropus vampyrus	76.84	0.00e+00	1108.00
IUUC-Rno-105728	Rattus norvegicus	78.55	0.00e+00	1174.00
IUUC-Sce-106404	Saccharomyces cerevisiae	46.43	9.00e-12	64.30
IUUC-Sha-106515	Sarcophilus harrisii	85.18	0.00e+00	847.00
IUUC-Smo-109517	Selaginella moellendorffii	40.30	3.00e-08	49.30
IUUC-Sar-113161	Sorex araneus	73.12	0.00e+00	1013.00
IUUC-Ssc-115314	Sus scrofa	71.92	0.00e+00	984.00
IUUC-Tgu-117012	Taeniopygia guttata	94.08	0.00e+00	1385.00
IUUC-Tru-118467	Takifugu rubripes	62.96	1.00e-169	590.00
IUUC-Tsy-119566	Tarsius syrichta	77.52	2.00e-160	559.00
IUUC-Tni-120830	Tetraodon nigroviridis	55.78	4.00e-175	608.00
IUUC-Tbe-128070	Tupaia belangeri	78.20	0.00e+00	768.00
IUUC-Ttr-128161	Tursiops truncatus	86.67	3.00e-124	439.00
IUUC-Xtr-132628	Xenopus tropicalis	76.50	0.00e+00	891.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence