iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-107622

Ensembl Protein ID

ENSSHAP00000021210.1

UniProt Accession

G3X0K5; G3X0K5_SARHA

Genbank Protein ID

ENSSHAP00000021210

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01111577

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000017981.1	ENSSHAT00000021382.1	ENSSHAP00000021210.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.60e-30	104.9	113	183

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 4    eyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaa.etkgnmqaaelLLktLvqkegWfrefl 73
             ++ll  lq++++++L+vtdv dk+l+  ll++e+++++  + e+ gn+ a+++LL+++ qke Wf+ fl
   Q: 113  QCVQLLDILQPTLVDKLLVTDVVDKCLEKALLTKEDRNRVVLLnENDGNERAVRELLSRIIQKEDWFSKFL 183
           5789**********************************987652799*********************996 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MSSEYSPENT FLNLILCFRP RLKQYIRVES VLDYLTFMGR AEKEQIQSTA VTRGNTTAAE 60
LLLHILEKGD WGPGWTQEFL NGLMNGGCTL AARYMNPDLA DLPSPSLEAS YDQCVQLLDI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTCTATC TGACTTGGAT GGGAATCCAT AGATTATATC TCTGGGTTCT CATGTGATTA 60
GAATGTGAGC TCCCATTAAA ATATGAGCTC TATTACAGCA TCTATTACAG CATCTATTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	71.11	0.00e+00	1381.00
IUUC-Apl-003900	Anas platyrhynchos	60.71	0.00e+00	1218.00
IUUC-Aca-005329	Anolis carolinensis	59.07	0.00e+00	1053.00
IUUC-Ame-011305	Astyanax mexicanus	56.96	0.00e+00	801.00
IUUC-Bta-012361	Bos taurus	72.55	0.00e+00	1370.00
IUUC-Cel-018230	Caenorhabditis elegans	25.86	2.00e-55	211.00
IUUC-Cja-018760	Callithrix jacchus	71.07	0.00e+00	1309.00
IUUC-Cfa-020321	Canis familiaris	71.35	0.00e+00	1337.00
IUUC-Cpo-022450	Cavia porcellus	69.34	0.00e+00	1346.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	32.52	4.00e-13	70.50
IUUC-Csa-024194	Chlorocebus sabaeus	73.18	0.00e+00	1314.00
IUUC-Cho-024364	Choloepus hoffmanni	65.39	0.00e+00	897.00
IUUC-Cin-025792	Ciona intestinalis	29.59	5.00e-72	265.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	33.06	8.00e-13	70.10
IUUC-Dre-028305	Danio rerio	55.20	0.00e+00	728.00
IUUC-Dno-029831	Dasypus novemcinctus	72.07	0.00e+00	1368.00
IUUC-Dor-030410	Dipodomys ordii	79.49	0.00e+00	969.00
IUUC-Ete-032950	Echinops telfairi	62.52	0.00e+00	709.00
IUUC-Eca-034279	Equus caballus	73.15	0.00e+00	1377.00
IUUC-Eeu-034678	Erinaceus europaeus	69.81	0.00e+00	1387.00
IUUC-Fca-035618	Felis catus	75.44	0.00e+00	853.00
IUUC-Fal-037106	Ficedula albicollis	60.72	0.00e+00	1130.00
IUUC-Fso-038398	Fusarium solani	26.36	6.00e-28	120.00
IUUC-Gmo-038598	Gadus morhua	51.34	0.00e+00	697.00
IUUC-Gga-040467	Gallus gallus	61.48	0.00e+00	1207.00
IUUC-Gac-042316	Gasterosteus aculeatus	47.84	0.00e+00	849.00
IUUC-Ggo-045461	Gorilla gorilla	72.41	0.00e+00	1310.00
IUUC-Hsa-045771	Homo sapiens	72.89	0.00e+00	1305.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	72.29	0.00e+00	1365.00
IUUC-Lch-049913	Latimeria chalumnae	65.53	0.00e+00	927.00
IUUC-Loc-052768	Lepisosteus oculatus	55.02	0.00e+00	1021.00
IUUC-Laf-053933	Loxodonta africana	72.83	0.00e+00	1343.00
IUUC-Mcc-054695	Macaca mulatta	73.28	0.00e+00	1320.00
IUUC-Meu-056829	Macropus eugenii	83.29	0.00e+00	1271.00
IUUC-Mga-059205	Meleagris gallopavo	61.61	0.00e+00	1206.00
IUUC-Mvi-060497	Microbotryum violaceum	30.19	4.00e-17	84.30
IUUC-Mmr-060703	Microcebus murinus	73.44	0.00e+00	1347.00
IUUC-Mdo-063079	Monodelphis domestica	81.84	0.00e+00	1666.00
IUUC-Mmu-064066	Mus musculus	70.45	0.00e+00	1397.00
IUUC-Mpu-066261	Mustela putorius furo	71.25	0.00e+00	1347.00
IUUC-Mlu-068196	Myotis lucifugus	71.26	0.00e+00	1325.00
IUUC-Nfi-068405	Neosartorya fischeri	25.56	2.00e-21	98.60
IUUC-Nle-069479	Nomascus leucogenys	71.90	0.00e+00	1312.00
IUUC-Opr-070717	Ochotona princeps	64.27	0.00e+00	964.00
IUUC-Ont-071702	Oreochromis niloticus	48.42	0.00e+00	894.00
IUUC-Oan-073639	Ornithorhynchus anatinus	67.27	0.00e+00	1215.00
IUUC-Ocu-074521	Oryctolagus cuniculus	71.86	0.00e+00	1360.00
IUUC-Ola-086351	Oryzias latipes	45.86	0.00e+00	819.00
IUUC-Oga-088539	Otolemur garnettii	70.71	0.00e+00	1338.00
IUUC-Oar-090186	Ovis aries	72.97	0.00e+00	1342.00
IUUC-Ptr-090575	Pan troglodytes	71.41	0.00e+00	1300.00
IUUC-Pan-092371	Papio anubis	73.48	0.00e+00	1320.00
IUUC-Psi-093072	Pelodiscus sinensis	64.66	0.00e+00	1307.00
IUUC-Pma-094345	Petromyzon marinus	44.30	1.00e-98	353.00
IUUC-Pfo-096401	Poecilia formosa	53.95	0.00e+00	711.00
IUUC-Pab-097623	Pongo abelii	72.70	0.00e+00	1310.00
IUUC-Pca-100993	Procavia capensis	67.31	0.00e+00	1117.00
IUUC-Pva-102227	Pteropus vampyrus	68.48	0.00e+00	1248.00
IUUC-Pgr-103529	Puccinia graminis	39.32	6.00e-16	80.10
IUUC-Rno-105198	Rattus norvegicus	69.78	0.00e+00	1398.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	26.26	6.30e-01	31.20
IUUC-Sar-113625	Sorex araneus	79.46	3.00e-149	522.00
IUUC-Ssc-116120	Sus scrofa	32.37	1.00e-85	310.00
IUUC-Tgu-117486	Taeniopygia guttata	59.15	0.00e+00	1148.00
IUUC-Tru-118445	Takifugu rubripes	45.94	0.00e+00	837.00
IUUC-Tsy-119512	Tarsius syrichta	70.74	0.00e+00	1280.00
IUUC-Tni-120711	Tetraodon nigroviridis	45.01	0.00e+00	865.00
IUUC-Tre-122194	Trichoderma reesei	34.78	1.00e-11	66.20
IUUC-Tme-126965	Tuber melanosporum	29.55	1.60e+00	27.70
IUUC-Tbe-127644	Tupaia belangeri	64.47	0.00e+00	1194.00
IUUC-Ttr-128989	Tursiops truncatus	67.70	0.00e+00	1328.00
IUUC-Vpa-130587	Vicugna pacos	68.87	0.00e+00	1085.00
IUUC-Xtr-132127	Xenopus tropicalis	54.27	0.00e+00	1046.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence