iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-060008

Ensembl Protein ID

ENSMGAP00000005809.2

UniProt Accession

G1N2F4; G1N2F4_MELGA

Protein Name

Uncharacterized protein

Gene Name

TRIO

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000005861.2	ENSMGAT00000006553.2	ENSMGAP00000005809.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-13	50.3	1611	1662

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk..elegkrGlfP 55
             v++d++a n++eLt+++G +v+v+e  +   +W+           +Gl+P
   Q: 1611 TVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTtdRSPAAEGLVP 1662
           679********************************97755334445678887 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

SGFRKNDEMK AMEVLPILKE KVAYLSGGRD KRGGPILTFP ARSNHDRIRQ EDLRRLISYL 60
ACIPSEEVCK RGFTVIVDMR GSKWDSIKPL LKILQESFPC CIHVALIIKP DNFWQKQRTN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGGGTTTC GCAAAAATGA TGAAATGAAG GCTATGGAAG TTTTGCCAAT TTTAAAGGAA 60
AAAGTCGCAT ACCTTTCAGG TACAGTTATT TTCTTTTGTT GTATAGTGCA TAACTGTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR001251--CRAL-TRIO_dom
IPR000219--DH-domain
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR013098--Ig_I-set
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain
IPR018159--Spectrin/alpha-actinin
IPR002017--Spectrin_repeat
IPR028570--TRIO

PROSITE

PS50191--CRAL_TRIO
PS50010--DH_2
PS50835--IG_LIKE
PS50003--PH_DOMAIN
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF00650--CRAL_TRIO
PF07679--I-set
PF00169--PH
PF00069--Pkinase
PF00621--RhoGEF
PF00018--SH3_1
PF00435--Spectrin

SMART

SM00409--IG
SM00408--IGc2
SM00233--PH
SM00325--RhoGEF
SM00220--S_TKc
SM00516--SEC14
SM00326--SH3
SM00150--SPEC

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001797	Ailuropoda melanoleuca	92.69	0.00e+00	5488.00
IUUC-Apl-003498	Anas platyrhynchos	97.13	0.00e+00	5385.00
IUUC-Bta-013121	Bos taurus	96.16	0.00e+00	4274.00
IUUC-Cja-018919	Callithrix jacchus	98.21	0.00e+00	4358.00
IUUC-Cfa-020547	Canis familiaris	97.84	0.00e+00	4328.00
IUUC-Cpo-022301	Cavia porcellus	97.90	0.00e+00	4360.00
IUUC-Csa-023889	Chlorocebus sabaeus	97.99	0.00e+00	4358.00
IUUC-Dre-028386	Danio rerio	88.95	0.00e+00	3919.00
IUUC-Dno-028888	Dasypus novemcinctus	91.26	0.00e+00	5418.00
IUUC-Dor-030992	Dipodomys ordii	90.80	0.00e+00	3962.00
IUUC-Ete-033167	Echinops telfairi	89.76	0.00e+00	1670.00
IUUC-Eca-033685	Equus caballus	97.66	0.00e+00	4313.00
IUUC-Fca-035647	Felis catus	97.10	0.00e+00	4347.00
IUUC-Fal-036845	Ficedula albicollis	99.11	0.00e+00	4401.00
IUUC-Gga-040959	Gallus gallus	97.80	0.00e+00	5823.00
IUUC-Gac-041349	Gasterosteus aculeatus	87.41	0.00e+00	3777.00
IUUC-Ggo-045170	Gorilla gorilla	98.38	0.00e+00	4355.00
IUUC-Hsa-046059	Homo sapiens	97.95	0.00e+00	4361.00
IUUC-Lch-050010	Latimeria chalumnae	89.82	0.00e+00	5274.00
IUUC-Loc-052783	Lepisosteus oculatus	92.63	0.00e+00	4120.00
IUUC-Laf-053884	Loxodonta africana	97.89	0.00e+00	4332.00
IUUC-Mcc-055804	Macaca mulatta	97.60	0.00e+00	4345.00
IUUC-Mmr-061081	Microcebus murinus	92.38	0.00e+00	5499.00
IUUC-Mdo-062888	Monodelphis domestica	99.22	0.00e+00	4034.00
IUUC-Mmu-063327	Mus musculus	98.03	0.00e+00	4315.00
IUUC-Mpu-066905	Mustela putorius furo	97.63	0.00e+00	4341.00
IUUC-Mlu-068215	Myotis lucifugus	94.54	0.00e+00	4257.00
IUUC-Nle-069414	Nomascus leucogenys	95.49	0.00e+00	4209.00
IUUC-Opr-070819	Ochotona princeps	94.40	0.00e+00	4167.00
IUUC-Ont-072678	Oreochromis niloticus	89.15	0.00e+00	3887.00
IUUC-Oan-072974	Ornithorhynchus anatinus	98.57	0.00e+00	4365.00
IUUC-Ocu-074919	Oryctolagus cuniculus	91.71	0.00e+00	5431.00
IUUC-Oga-088068	Otolemur garnettii	92.67	0.00e+00	5538.00
IUUC-Oar-090050	Ovis aries	94.43	0.00e+00	4213.00
IUUC-Ptr-090841	Pan troglodytes	97.99	0.00e+00	4361.00
IUUC-Psi-093088	Pelodiscus sinensis	95.99	0.00e+00	5715.00
IUUC-Pfo-097201	Poecilia formosa	87.16	0.00e+00	2548.00
IUUC-Pab-098130	Pongo abelii	98.16	0.00e+00	4355.00
IUUC-Pca-100839	Procavia capensis	93.31	0.00e+00	2553.00
IUUC-Pva-102115	Pteropus vampyrus	94.43	0.00e+00	2894.00
IUUC-Rno-105207	Rattus norvegicus	97.55	0.00e+00	4307.00
IUUC-Sha-107011	Sarcophilus harrisii	90.45	0.00e+00	4320.00
IUUC-Tgu-116970	Taeniopygia guttata	96.52	0.00e+00	5687.00
IUUC-Tru-117758	Takifugu rubripes	87.59	0.00e+00	3853.00
IUUC-Ttr-128857	Tursiops truncatus	89.47	0.00e+00	3939.00
IUUC-Xtr-131909	Xenopus tropicalis	87.41	0.00e+00	5229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence