iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-097203

Ensembl Protein ID

ENSPFOP00000015400.2

UniProt Accession

A0A087YBJ7; A0A087YBJ7_POEFO

Genbank Protein ID

ENSPFOP00000015400

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01015925

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000015224.2	ENSPFOT00000015422.2	ENSPFOP00000015400.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.00e-127	424.8	394	726

Active Site

Position(s)	Description	Evidence
695	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkkrl+v+f+gEegld+gGv+re+l+ll++e+ np++glf+ys ++ +tlq+npds + np+hl++F+f+Gr++g+a++++++++ 
   Q: 394  PKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSI-NPDHLSYFHFVGRVMGLAVFHSHYING 481
           689*********************************************************9.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            ++ +fyk+llgk+++l+dle++dpel+ksl +i+en   di+   ld tf+v+++ +g+ +++eLkp+G+nipVt+eNk+eYv+l+v+
   Q: 482  SFTLPFYKQLLGKPIQLNDLETTDPELHKSLVWILEN---DITSV-LDHTFCVEHNAFGKFSQHELKPNGRNIPVTEENKKEYVRLYVN 566
           ***********************************99...99998.******************************************* PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +gi+ q+ a+++Gf+e+ip++ll+ F+++elel+i G  +id+ d+k++t+ k+ +t +s++++wFw+++e+fs+e r ++LqFv
   Q: 567  WRFMRGIEAQFLALQKGFSELIPQHLLKPFDHKELELIIGGLGKIDLADWKANTRLKH-CTGESNVVRWFWQAVEAFSEERRGRLLQFV 654
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tgs r+Pl+Gf++l+    prlf+i+  da++++lP+++TCfn++++P+Y+s+e+l+ekLl+A+eet gF +
   Q: 655  TGSTRVPLQGFKALQgsagPRLFTIHLiDANTENLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAV 726
           ***************************99999**************************************76 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MSNPGSRRNG SSIKIRLTVL CAKNLAKKDF FRLPDPFAKV VVDGSGQCHS TDTVKSTLDP 60
KWNQHYDLYI GKTDSITISI WNHKKIHKRQ GAGFLGCIRL LSNAISRLKD TGYQRLDLCK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAACGCATC AGTCAACTTT TTGTCGTATT ATACGGGCGC GCTCACGCCA TCCGGCGCGA 60
GCACGCAGCG GTGAGAACAT GACGTCAGCA GCGTACGTGC TTAAGCCTGC CCGAAAATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001459	Ailuropoda melanoleuca	79.92	0.00e+00	1233.00
IUUC-Apl-004155	Anas platyrhynchos	81.94	0.00e+00	1263.00
IUUC-Aca-005238	Anolis carolinensis	84.28	0.00e+00	1277.00
IUUC-Ame-010901	Astyanax mexicanus	89.04	0.00e+00	1350.00
IUUC-Bta-013221	Bos taurus	78.53	0.00e+00	1190.00
IUUC-Cja-018985	Callithrix jacchus	82.25	0.00e+00	1289.00
IUUC-Cfa-020568	Canis familiaris	80.08	0.00e+00	1238.00
IUUC-Cpo-022531	Cavia porcellus	81.85	0.00e+00	1281.00
IUUC-Csa-024145	Chlorocebus sabaeus	85.35	0.00e+00	1308.00
IUUC-Cho-024963	Choloepus hoffmanni	67.09	0.00e+00	789.00
IUUC-Dre-028341	Danio rerio	89.04	0.00e+00	1351.00
IUUC-Dno-029705	Dasypus novemcinctus	80.13	0.00e+00	1223.00
IUUC-Eca-034125	Equus caballus	81.42	0.00e+00	1247.00
IUUC-Fca-035905	Felis catus	83.22	0.00e+00	1246.00
IUUC-Fal-037336	Ficedula albicollis	85.00	0.00e+00	1259.00
IUUC-Gmo-039486	Gadus morhua	80.68	0.00e+00	1161.00
IUUC-Gga-040218	Gallus gallus	84.38	0.00e+00	1300.00
IUUC-Gac-041707	Gasterosteus aculeatus	95.89	0.00e+00	1394.00
IUUC-Ggo-045408	Gorilla gorilla	77.14	0.00e+00	1157.00
IUUC-Hsa-045878	Homo sapiens	82.25	0.00e+00	1288.00
IUUC-Itr-048317	Ictidomys tridecemlineatus	81.93	0.00e+00	1252.00
IUUC-Loc-052628	Lepisosteus oculatus	81.89	0.00e+00	1308.00
IUUC-Laf-053644	Loxodonta africana	80.11	0.00e+00	1214.00
IUUC-Mcc-055479	Macaca mulatta	77.57	0.00e+00	1146.00
IUUC-Mga-059723	Meleagris gallopavo	82.08	0.00e+00	1246.00
IUUC-Mdo-063005	Monodelphis domestica	85.12	0.00e+00	1303.00
IUUC-Mmu-063634	Mus musculus	84.59	0.00e+00	1276.00
IUUC-Mpu-065898	Mustela putorius furo	83.63	0.00e+00	1251.00
IUUC-Mlu-067584	Myotis lucifugus	81.06	0.00e+00	1250.00
IUUC-Nle-069033	Nomascus leucogenys	81.95	0.00e+00	1253.00
IUUC-Ont-072265	Oreochromis niloticus	92.37	0.00e+00	1409.00
IUUC-Oan-073621	Ornithorhynchus anatinus	80.05	0.00e+00	1271.00
IUUC-Ocu-073960	Oryctolagus cuniculus	80.80	0.00e+00	1222.00
IUUC-Ola-086960	Oryzias latipes	83.64	0.00e+00	1217.00
IUUC-Oga-088579	Otolemur garnettii	82.25	0.00e+00	1288.00
IUUC-Oar-090396	Ovis aries	81.12	0.00e+00	1201.00
IUUC-Ptr-091624	Pan troglodytes	82.25	0.00e+00	1288.00
IUUC-Pan-092479	Papio anubis	81.95	0.00e+00	1254.00
IUUC-Pab-097540	Pongo abelii	81.58	0.00e+00	1217.00
IUUC-Rno-105396	Rattus norvegicus	84.59	0.00e+00	1276.00
IUUC-Sha-107216	Sarcophilus harrisii	81.45	0.00e+00	1266.00
IUUC-Ssc-116413	Sus scrofa	82.79	0.00e+00	1234.00
IUUC-Tgu-116723	Taeniopygia guttata	81.95	0.00e+00	1238.00
IUUC-Tru-117843	Takifugu rubripes	91.41	0.00e+00	1393.00
IUUC-Tsy-119455	Tarsius syrichta	80.98	0.00e+00	1163.00
IUUC-Tni-120037	Tetraodon nigroviridis	91.71	0.00e+00	1316.00
IUUC-Tbe-127879	Tupaia belangeri	68.66	0.00e+00	993.00
IUUC-Ttr-128423	Tursiops truncatus	80.72	0.00e+00	1180.00
IUUC-Xtr-132237	Xenopus tropicalis	80.47	0.00e+00	1260.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence