iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002167

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01144970

Gene Name

KLHL41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000010622.1	ENSAMET00000011661.1	ENSAMEP00000011182.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.60e-19	68.4	35	101
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.30e-10	38.4	133	163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+ g++  ++h+++L+a+S++F+  fl+e++e+k k++v+++ v+p v+  ++k+lY+ ++d+n+
   Q: 35   DCTLKAGDKSLPCHRLILSACSPYFREYFLSEMDEGK-KKEVVLDNVDPAVLDLIIKYLYSASIDLND 101
           9************************************.***************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Ncl+ilr++ l+dcp+L+ +a++f+++ F
   Q: 133  PGNCLAILRLGLLLDCPRLAISAREFVSDRF 163
           56***************************99 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

KMDSQRELTE ELRLYQSTLL QDGLKDLLEE KKFIDCTLKA GDKSLPCHRL ILSACSPYFR 60
EYFLSEMDEG KKKEVVLDNV DPAVLDLIIK YLYSASIDLN DGNVQDIFAL ASRFQIPSVF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAATGGATT CCCAGCGGGA ACTCACAGAG GAACTGCGGC TTTACCAATC CACCCTTCTT 60
CAGGATGGTC TAAAAGATCT CCTGGAGGAA AAAAAATTCA TCGATTGCAC CCTAAAAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0031430--C:M band
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003866	Anas platyrhynchos	86.16	0.00e+00	1041.00
IUUC-Ame-011172	Astyanax mexicanus	62.35	0.00e+00	758.00
IUUC-Bta-012925	Bos taurus	97.52	0.00e+00	1186.00
IUUC-Bci-013875	Botrytis cinerea	29.11	2.00e-18	85.90
IUUC-Cja-019348	Callithrix jacchus	96.86	0.00e+00	1182.00
IUUC-Cfa-020782	Canis familiaris	98.85	0.00e+00	1200.00
IUUC-Cpo-021825	Cavia porcellus	93.40	0.00e+00	1135.00
IUUC-Csa-023184	Chlorocebus sabaeus	96.74	0.00e+00	1011.00
IUUC-Cin-025237	Ciona intestinalis	28.99	4.00e-69	255.00
IUUC-Dre-028278	Danio rerio	60.40	0.00e+00	774.00
IUUC-Dno-029516	Dasypus novemcinctus	95.54	0.00e+00	1169.00
IUUC-Dor-030850	Dipodomys ordii	93.47	0.00e+00	761.00
IUUC-Dse-031340	Dothistroma septosporum	33.78	1.00e-05	43.90
IUUC-Ete-032697	Echinops telfairi	93.89	0.00e+00	1127.00
IUUC-Eca-033714	Equus caballus	97.36	0.00e+00	1189.00
IUUC-Eeu-035245	Erinaceus europaeus	94.73	0.00e+00	1071.00
IUUC-Gmo-039392	Gadus morhua	57.96	0.00e+00	733.00
IUUC-Ggr-040041	Gaeumannomyces graminis	28.47	4.00e-08	52.00
IUUC-Gga-041106	Gallus gallus	85.64	0.00e+00	1053.00
IUUC-Gac-042252	Gasterosteus aculeatus	61.49	0.00e+00	781.00
IUUC-Ggo-044817	Gorilla gorilla	96.87	0.00e+00	1182.00
IUUC-Hsa-046620	Homo sapiens	97.03	0.00e+00	1181.00
IUUC-Lch-050477	Latimeria chalumnae	69.80	0.00e+00	857.00
IUUC-Loc-051955	Lepisosteus oculatus	70.02	0.00e+00	913.00
IUUC-Laf-053500	Loxodonta africana	96.37	0.00e+00	1171.00
IUUC-Mcc-055316	Macaca mulatta	96.86	0.00e+00	1182.00
IUUC-Mmr-061444	Microcebus murinus	97.52	0.00e+00	1184.00
IUUC-Mmu-064147	Mus musculus	95.87	0.00e+00	1170.00
IUUC-Mlu-067481	Myotis lucifugus	94.22	0.00e+00	1155.00
IUUC-Ncr-068938	Neurospora crassa	30.10	7.00e-08	52.00
IUUC-Nle-069339	Nomascus leucogenys	97.19	0.00e+00	1184.00
IUUC-Opr-070703	Ochotona princeps	96.53	0.00e+00	1132.00
IUUC-Ont-072420	Oreochromis niloticus	60.43	0.00e+00	798.00
IUUC-Oan-073476	Ornithorhynchus anatinus	92.90	0.00e+00	1139.00
IUUC-Ocu-074248	Oryctolagus cuniculus	96.71	0.00e+00	1186.00
IUUC-Ola-086361	Oryzias latipes	61.96	0.00e+00	785.00
IUUC-Oar-090349	Ovis aries	97.03	0.00e+00	1183.00
IUUC-Pan-092069	Papio anubis	97.03	0.00e+00	1184.00
IUUC-Psi-093671	Pelodiscus sinensis	88.28	0.00e+00	1053.00
IUUC-Pma-094586	Petromyzon marinus	57.14	5.00e-94	337.00
IUUC-Pfo-096122	Poecilia formosa	62.91	0.00e+00	816.00
IUUC-Pab-098711	Pongo abelii	96.86	0.00e+00	1181.00
IUUC-Pca-100495	Procavia capensis	87.95	0.00e+00	1050.00
IUUC-Pva-102401	Pteropus vampyrus	96.86	0.00e+00	1181.00
IUUC-Rno-105969	Rattus norvegicus	95.38	0.00e+00	1165.00
IUUC-Sar-113405	Sorex araneus	93.40	0.00e+00	1129.00
IUUC-Tgu-116725	Taeniopygia guttata	85.81	0.00e+00	1073.00
IUUC-Tru-117743	Takifugu rubripes	59.05	0.00e+00	763.00
IUUC-Tsy-119225	Tarsius syrichta	89.77	0.00e+00	1077.00
IUUC-Tni-120547	Tetraodon nigroviridis	62.58	0.00e+00	797.00
IUUC-Ttr-128645	Tursiops truncatus	97.36	0.00e+00	1185.00
IUUC-Vpa-130714	Vicugna pacos	97.85	0.00e+00	1189.00
IUUC-Xtr-132144	Xenopus tropicalis	75.95	0.00e+00	940.00
IUUC-Xma-133860	Xiphophorus maculatus	63.08	0.00e+00	817.00
IUUC-Yli-134535	Yarrowia lipolytica	23.44	8.00e-07	47.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence