iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052474

Ensembl Protein ID

ENSLOCP00000006240.1

UniProt Accession

W5MCY1; W5MCY1_LEPOC

Genbank Protein ID

ENSLOCP00000006240

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01005782

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000005178.1	ENSLOCT00000006248.1	ENSLOCP00000006240.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-106	357.1	745	1567

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln+ np ++ g+++k++ +l++elw++++k+v+p +l  +++k+a++f+g
   Q: 745  TGLSNLGNTCFMNSSIQCVSNTKPLTQYFISgRHLYELNRMNPIGMRGHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNG 831
           7******************************99****************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a+e++ ++nks+++dlF+gqlksq+kc++c+++s r++p
   Q: 832  FQQQDSQELLAFLLDGLHEDLNRVHDKPYVELKDSD--GRPDWevaseAWENHLRRNKSIVVDLFHGQLKSQVKCKTCGHISARFDP 916
           ********************************9999..5555566777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 917  FNFLSLPLPMDSYMHLEitvikldgstpvryglrlnmdekytglkkqlselcvlkpdqillaevhasniknfpldnqkvrlsvsgfl 1003
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1004 cafeipvpgsptsisspssiafievaplangipamasngnslipngmpstvvpcgtektlangvpnghvvplqdspftgyiiaihrk 1090
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1091 mmrtelyflssqknrpslfgmplivpctvhtrkrdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgnscar 1177
           *************************************************************************************** PP
   S: 186  ................................................................slqdcLesftkeeelegenkyyc 208
                                                                           sl++cL++ft+eeel ++++yyc
   Q: 1178 cpwyrfcrgctidcneerasvgnayiavdwdptalhlryqtsqervveehesvelsrraqaepiSLDSCLRAFTSEEELGEDEMYYC 1264
           *************************************************************************************** PP
   S: 209  ekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................... 267
           +kck ++ a+kkl+l++lP+vLi+hLkRf+f +   + +k +k v+fp+e +d s f++                            
   Q: 1265 SKCKTHRLATKKLDLWRLPPVLIIHLKRFQFVNG--RWIKSQKIVKFPRErFDPSAFLVPrdagacqrgreecqgeepaetrgaevg 1349
           *****************************99775..5569********999*********888888888887777777777777777 PP
   S: 268  ...................................................peekqke............................. 274
                                                              +     +                             
   Q: 1350 vaqtagsgdagtaapgtavthsikaspgpgrkstnplsrnsspcnspktpgK-----Nkgrlrlpqlgsrhklsnskenldscregs 1431
           7777777777777777777777777777666666666666665555555550.....055555555555555666666666667777 PP
   S: 275  ............................................................................kkkYeLiavvv 285
                                                                                       k  Y+L+a+ +
   Q: 1432 geldqgpaadleassgvgvaegngqdvwpgeapgrdceavmvnglglghepgqsnghaetimdsesfhhqrdeiclKPVYNLYAISC 1518
           7777777777777777777777777778888888888888888888888888888888899999999999999999*********** PP
   S: 286  HsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           HsG l++GHYv+y+kn ++kW++++Ds+++ev+ ee+ +   ++aY+lfY++
   Q: 1519 HSGILGGGHYVTYAKNPNEKWYCYNDSSCKEVHSEEIDT---DSAYILFYEQ 1567
           ***************************************...********97 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MGAKESRIGF LSYDEAVKRV TDVELKRLKD AFRRTSGLSC YMTQQCFFRE VLGDGMPPKV 60
AEVIYNSFGG TSKGLHFNNL IVGLVLLTRG RDEEKAKYIF SLFANESGSY VVREDMESML 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGCGCCCGG CGCCTGCGCG CTGCAGTGCC GCTGTAGCTG TTTTCCTACC TCGTCAGGTG 60
ACCCGACATT AGGTTCGGTC ATGTGACCAA GTATGGAGGC GTCGGCGAGG AAGAGCGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	75.48	0.00e+00	2085.00
IUUC-Apl-003272	Anas platyrhynchos	76.13	0.00e+00	2413.00
IUUC-Aca-005057	Anolis carolinensis	79.97	0.00e+00	2147.00
IUUC-Ame-010781	Astyanax mexicanus	79.25	0.00e+00	2565.00
IUUC-Bta-013502	Bos taurus	74.82	0.00e+00	2275.00
IUUC-Cja-018754	Callithrix jacchus	77.62	0.00e+00	2491.00
IUUC-Cfa-020526	Canis familiaris	77.06	0.00e+00	2454.00
IUUC-Cpo-021568	Cavia porcellus	73.49	0.00e+00	2229.00
IUUC-Csa-023143	Chlorocebus sabaeus	77.32	0.00e+00	2463.00
IUUC-Cho-024603	Choloepus hoffmanni	49.92	2.00e-151	530.00
IUUC-Cin-025583	Ciona intestinalis	53.13	0.00e+00	845.00
IUUC-Csv-026344	Ciona savignyi	45.21	0.00e+00	1169.00
IUUC-Dre-028121	Danio rerio	80.69	0.00e+00	2555.00
IUUC-Dno-029911	Dasypus novemcinctus	76.49	0.00e+00	2391.00
IUUC-Dor-030608	Dipodomys ordii	58.52	6.00e-170	592.00
IUUC-Dme-032094	Drosophila melanogaster	46.03	2.00e-121	431.00
IUUC-Ete-032639	Echinops telfairi	73.87	0.00e+00	1256.00
IUUC-Eca-034253	Equus caballus	77.57	0.00e+00	2432.00
IUUC-Eeu-035084	Erinaceus europaeus	68.55	0.00e+00	1353.00
IUUC-Fca-035474	Felis catus	75.11	0.00e+00	1964.00
IUUC-Fal-036985	Ficedula albicollis	78.46	0.00e+00	2465.00
IUUC-Gmo-039568	Gadus morhua	76.39	0.00e+00	2401.00
IUUC-Gga-040509	Gallus gallus	76.77	0.00e+00	2492.00
IUUC-Gac-041757	Gasterosteus aculeatus	77.52	0.00e+00	2445.00
IUUC-Ggo-044956	Gorilla gorilla	75.64	0.00e+00	1535.00
IUUC-Hsa-046107	Homo sapiens	77.44	0.00e+00	2482.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	69.49	0.00e+00	859.00
IUUC-Lch-050681	Latimeria chalumnae	75.61	0.00e+00	2351.00
IUUC-Laf-054273	Loxodonta africana	77.33	0.00e+00	2483.00
IUUC-Mcc-054718	Macaca mulatta	77.50	0.00e+00	2489.00
IUUC-Meu-056558	Macropus eugenii	63.30	0.00e+00	1233.00
IUUC-Mga-059892	Meleagris gallopavo	77.25	0.00e+00	2402.00
IUUC-Mmr-060866	Microcebus murinus	78.18	0.00e+00	2517.00
IUUC-Mdo-062607	Monodelphis domestica	78.18	0.00e+00	2513.00
IUUC-Mmu-063797	Mus musculus	77.14	0.00e+00	2511.00
IUUC-Mpu-066121	Mustela putorius furo	77.96	0.00e+00	2507.00
IUUC-Mlu-067581	Myotis lucifugus	76.64	0.00e+00	2470.00
IUUC-Nle-069916	Nomascus leucogenys	75.57	0.00e+00	2373.00
IUUC-Opr-071073	Ochotona princeps	69.87	0.00e+00	992.00
IUUC-Ont-071310	Oreochromis niloticus	83.47	0.00e+00	2226.00
IUUC-Oan-073356	Ornithorhynchus anatinus	77.32	0.00e+00	2496.00
IUUC-Ocu-074216	Oryctolagus cuniculus	77.86	0.00e+00	2496.00
IUUC-Ola-087434	Oryzias latipes	77.44	0.00e+00	2368.00
IUUC-Oga-089034	Otolemur garnettii	76.93	0.00e+00	2400.00
IUUC-Oar-090369	Ovis aries	77.93	0.00e+00	2448.00
IUUC-Ptr-090605	Pan troglodytes	77.57	0.00e+00	2487.00
IUUC-Pan-092381	Papio anubis	77.22	0.00e+00	2409.00
IUUC-Psi-093819	Pelodiscus sinensis	78.20	0.00e+00	2457.00
IUUC-Pma-094480	Petromyzon marinus	64.08	0.00e+00	1451.00
IUUC-Pfo-096561	Poecilia formosa	77.38	0.00e+00	2405.00
IUUC-Pab-097643	Pongo abelii	75.35	0.00e+00	2387.00
IUUC-Pca-100944	Procavia capensis	67.68	0.00e+00	862.00
IUUC-Pva-102732	Pteropus vampyrus	69.13	0.00e+00	2142.00
IUUC-Rno-105113	Rattus norvegicus	77.11	0.00e+00	2452.00
IUUC-Sha-107608	Sarcophilus harrisii	63.73	1.00e-126	446.00
IUUC-Sar-113201	Sorex araneus	66.24	0.00e+00	1364.00
IUUC-Ssc-115469	Sus scrofa	62.12	3.00e-122	431.00
IUUC-Tgu-117322	Taeniopygia guttata	78.13	0.00e+00	2535.00
IUUC-Tru-118705	Takifugu rubripes	75.37	0.00e+00	676.00
IUUC-Tsy-119433	Tarsius syrichta	69.80	0.00e+00	1207.00
IUUC-Tni-120631	Tetraodon nigroviridis	74.50	0.00e+00	2308.00
IUUC-Tbe-127553	Tupaia belangeri	78.88	4.00e-178	619.00
IUUC-Ttr-128260	Tursiops truncatus	76.79	0.00e+00	2437.00
IUUC-Vpa-130479	Vicugna pacos	73.06	0.00e+00	2279.00
IUUC-Xtr-132686	Xenopus tropicalis	77.65	0.00e+00	2437.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence