iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089760

Ensembl Protein ID

ENSOARP00000001892.1

UniProt Accession

W5NUP8; W5NUP8_SHEEP

Genbank Protein ID

ENSOARP00000001892

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01069566

Gene Name

USP42

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000001803.1	ENSOART00000001939.1	ENSOARP00000001892.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-81	274.4	111	410

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC+ N++LQcL+ +p+l++++l+ ++++++++     +  ++++++q  +++ +++   +++p  +++ ++++a++f+  +q
   Q: 111  GLQNLGNTCFANAALQCLTYTPPLANYMLShEHSKTCHA-----EGFCMMCTMQAHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQ 194
           9*****************************445555544.....578****************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++ +d++++++                  l+ +++ + +++ ++l+ ++F+g l+s++kcl+c+ vs +++p ld++l+++ 
   Q: 195  EDAHEFLQYTVDAMQKAC------------------LNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKA 265
           ******************..................3344567789999**************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            +     s++++Le+f+k+e+l+gen y+c+kckk + a+k++++++ ++vL+l LkRf    ++    ki k v++p+ Ld++p++++
   Q: 266  AQ-----SVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRF----ANFTGGKIAKDVKYPEYLDIRPYMSQ 345
           **.....9***************************************************....668889******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           p+ +   + +Y L+av+vH+G +++ GHY++y+k ++g W++++Ds V++++  +vl+   ++aYvlfY r
   Q: 346  PNGE---PIIYVLYAVLVHTGfNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLS---QQAYVLFYIR 410
           9977...8**************************************************...********87 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MTIVDKAESS DPSTYQNQPG SSEAVSPGDM DAGSASWGAV SSLNDVSNHT LSLGPVPGAV 60
VYSSSSVPEK SKPSPQKDQA LGDGIAPPQK VLFPSEKICL KWQQTHRVGA GLQNLGNTCF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAGTCACC TGTTCAGCAC GTGTGGGGAG AGCTTTCCCT GTGCCAGGTG AGGGTGCACA 60
AACAGGAACA CGAGGGAGAG GAGCGTGGCA GTCTGCCCCG GAAACCAGCA AAGGGTGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000401	Aegilops tauschii	38.91	1.00e-70	261.00
IUUC-Aml-002303	Ailuropoda melanoleuca	70.08	0.00e+00	1362.00
IUUC-Apl-003459	Anas platyrhynchos	48.98	0.00e+00	632.00
IUUC-Aca-004440	Anolis carolinensis	51.24	0.00e+00	920.00
IUUC-Ath-006710	Arabidopsis thaliana	42.36	9.00e-76	278.00
IUUC-Ago-007836	Ashbya gossypii	26.70	6.00e-34	139.00
IUUC-Ame-011358	Astyanax mexicanus	71.84	0.00e+00	657.00
IUUC-Bta-012803	Bos taurus	91.40	0.00e+00	2122.00
IUUC-Cja-019199	Callithrix jacchus	67.78	0.00e+00	1442.00
IUUC-Cfa-020597	Canis familiaris	73.18	0.00e+00	1599.00
IUUC-Cpo-021945	Cavia porcellus	63.72	0.00e+00	1434.00
IUUC-Csa-023485	Chlorocebus sabaeus	70.85	0.00e+00	1167.00
IUUC-Cho-024575	Choloepus hoffmanni	58.02	0.00e+00	1051.00
IUUC-Cne-027049	Cryptococcus neoformans	31.86	6.00e-38	152.00
IUUC-Dre-028442	Danio rerio	70.70	0.00e+00	639.00
IUUC-Dno-029673	Dasypus novemcinctus	69.93	0.00e+00	1658.00
IUUC-Ete-033088	Echinops telfairi	91.79	0.00e+00	647.00
IUUC-Eca-033579	Equus caballus	71.63	0.00e+00	1561.00
IUUC-Eeu-034511	Erinaceus europaeus	49.69	5.00e-167	582.00
IUUC-Fca-035792	Felis catus	71.44	0.00e+00	1505.00
IUUC-Fal-037075	Ficedula albicollis	49.81	0.00e+00	699.00
IUUC-Gga-040504	Gallus gallus	41.03	0.00e+00	723.00
IUUC-Ggo-044798	Gorilla gorilla	64.21	0.00e+00	962.00
IUUC-Hsa-046072	Homo sapiens	71.78	0.00e+00	1182.00
IUUC-Hvu-047620	Hordeum vulgare	41.12	8.00e-74	272.00
IUUC-Itr-048078	Ictidomys tridecemlineatus	70.70	0.00e+00	1667.00
IUUC-Lch-049867	Latimeria chalumnae	65.30	0.00e+00	890.00
IUUC-Loc-052621	Lepisosteus oculatus	70.36	0.00e+00	661.00
IUUC-Laf-054330	Loxodonta africana	82.70	0.00e+00	1136.00
IUUC-Mcc-054900	Macaca mulatta	83.04	0.00e+00	670.00
IUUC-Mga-059501	Meleagris gallopavo	38.14	0.00e+00	647.00
IUUC-Mvi-060547	Microbotryum violaceum	45.62	1.00e-80	294.00
IUUC-Mmr-060864	Microcebus murinus	70.64	0.00e+00	1642.00
IUUC-Mdo-062395	Monodelphis domestica	58.65	0.00e+00	1396.00
IUUC-Mmu-064236	Mus musculus	64.04	0.00e+00	1414.00
IUUC-Mpu-065822	Mustela putorius furo	73.95	0.00e+00	1644.00
IUUC-Mlu-067091	Myotis lucifugus	70.51	0.00e+00	1506.00
IUUC-Nle-069004	Nomascus leucogenys	67.49	0.00e+00	1420.00
IUUC-Opr-071170	Ochotona princeps	58.01	0.00e+00	981.00
IUUC-Ont-071832	Oreochromis niloticus	63.77	0.00e+00	628.00
IUUC-Oan-073711	Ornithorhynchus anatinus	53.93	0.00e+00	1189.00
IUUC-Ocu-074596	Oryctolagus cuniculus	85.98	0.00e+00	941.00
IUUC-Oga-088641	Otolemur garnettii	69.18	0.00e+00	1574.00
IUUC-Ptr-091445	Pan troglodytes	71.16	0.00e+00	1173.00
IUUC-Pan-092484	Papio anubis	82.15	0.00e+00	1105.00
IUUC-Psi-093277	Pelodiscus sinensis	50.80	0.00e+00	1033.00
IUUC-Pma-094651	Petromyzon marinus	38.24	2.00e-56	212.00
IUUC-Pfo-096469	Poecilia formosa	65.47	0.00e+00	634.00
IUUC-Pab-097794	Pongo abelii	68.40	0.00e+00	1049.00
IUUC-Ppe-101678	Prunus persica	46.25	7.00e-82	298.00
IUUC-Pva-103238	Pteropus vampyrus	67.17	0.00e+00	1385.00
IUUC-Rno-105068	Rattus norvegicus	64.43	0.00e+00	1416.00
IUUC-Sha-106713	Sarcophilus harrisii	59.45	0.00e+00	1415.00
IUUC-Smo-108763	Selaginella moellendorffii	47.73	2.00e-80	291.00
IUUC-Sar-113340	Sorex araneus	79.97	0.00e+00	1028.00
IUUC-Tgu-117149	Taeniopygia guttata	41.10	0.00e+00	755.00
IUUC-Tru-117776	Takifugu rubripes	70.48	5.00e-172	598.00
IUUC-Tsy-118974	Tarsius syrichta	69.07	0.00e+00	1568.00
IUUC-Tni-120774	Tetraodon nigroviridis	74.68	1.00e-169	589.00
IUUC-Tca-120936	Theobroma cacao	45.93	5.00e-84	306.00
IUUC-Tbe-128006	Tupaia belangeri	85.66	2.00e-120	427.00
IUUC-Ttr-128764	Tursiops truncatus	71.75	0.00e+00	1528.00
IUUC-Vvi-131535	Vitis vinifera	46.65	2.00e-86	314.00
IUUC-Xtr-132544	Xenopus tropicalis	53.94	7.00e-175	607.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence