iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-107607

Ensembl Protein ID

ENSSHAP00000017982.1

UniProt Accession

G3WRC7; G3WRC7_SARHA

Genbank Protein ID

ENSSHAP00000017982

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01220318

Gene Name

TSG101

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000015267.1	ENSSHAT00000018131.1	ENSSHAP00000017982.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E2/UEV	95.13	2.00e-172	602.00	IUUC-Hsa-046686
UBD/UBC-like/UBD_UEV	95.13	2.00e-172	602.00	IUUC-Hsa-046686
UBD/UBC-like/UBD_UEV	92.55	5.00e-168	587.00	IUUC-Mmu-063151
E2/UEV	30.00	6.00e-10	60.10	IUUC-Sce-106262
UBD/UBC-like/UBD_UEV	30.00	6.00e-10	60.10	IUUC-Sce-106262

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MIKIFVSFLL VFNDGNSREL MSLTGTIPVP YRGNTYNIPI CLWLLDTYPY NPPICFVKPT 60
SSMTIKTGKH VDANGKIYLP YLHEWKHPQS DLLGLIQVMI VVFGEEPPVF SRPTVSASYP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTTTTCAA AGACTGGGTT TTTTTTGTTT TTTTTTTAAT TTGTTTGTTT GTTTTTTTGC 60
TGAGGCTATT GGGGTTTATT GAATTGCCCA GGGTCACATA GCTAGGAAGT GTTAAGTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR017916--SB_dom
IPR016135--UBQ-conjugating_enzyme/RWD
IPR008883--UEV_N

PROSITE

PS51312--SB
PS51322--UEV

Pfam

PF05743--UEV
PF09454--Vps23_core

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0000813--C:ESCRT I complex
GO:0070062--C:extracellular exosome
GO:0005770--C:late endosome
GO:0005730--C:nucleolus
GO:0005886--C:plasma membrane
GO:0003714--F:transcription corepressor activity
GO:0046790--F:virion binding
GO:0007050--P:cell cycle arrest
GO:0006464--P:cellular protein modification process
GO:1990182--P:exosomal secretion
GO:0030216--P:keratinocyte differentiation
GO:0008285--P:negative regulation of cell proliferation
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1903543--P:positive regulation of exosomal secretion
GO:2000397--P:positive regulation of ubiquitin-dependent endocytosis
GO:1903774--P:positive regulation of viral budding via host ESCRT complex
GO:1902188--P:positive regulation of viral release from host cell
GO:0015031--P:protein transport
GO:0001558--P:regulation of cell growth
GO:1903551--P:regulation of extracellular exosome assembly
GO:0043405--P:regulation of MAP kinase activity
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0046755--P:viral budding

KEGG

shr:100922408

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001072	Aegilops tauschii	41.51	1.00e-20	93.60
IUUC-Aml-002415	Ailuropoda melanoleuca	94.27	0.00e+00	642.00
IUUC-Atr-002875	Amborella trichopoda	31.67	1.00e-35	144.00
IUUC-Apl-003473	Anas platyrhynchos	90.91	3.00e-179	620.00
IUUC-Aca-004573	Anolis carolinensis	91.14	7.00e-174	602.00
IUUC-Aly-006164	Arabidopsis lyrata	47.50	1.00e-18	87.00
IUUC-Ath-006575	Arabidopsis thaliana	47.50	9.00e-19	87.80
IUUC-Ago-007755	Ashbya gossypii	25.30	7.00e-05	41.60
IUUC-Acl-008218	Aspergillus clavatus	39.81	7.00e-21	95.10
IUUC-Afl-008597	Aspergillus flavus	41.75	8.00e-22	98.60
IUUC-Afu-009017	Aspergillus fumigatus	38.00	8.00e-19	88.60
IUUC-Ani-009468	Aspergillus nidulans	42.00	2.00e-18	87.40
IUUC-Ang-009755	Aspergillus niger	38.00	9.00e-19	88.60
IUUC-Aor-010072	Aspergillus oryzae	41.75	9.00e-22	98.20
IUUC-Ate-010400	Aspergillus terreus	39.81	6.00e-21	95.50
IUUC-Ame-011620	Astyanax mexicanus	81.38	1.00e-168	585.00
IUUC-Bgr-012136	Blumeria graminis	37.50	1.00e-18	87.80
IUUC-Bta-012557	Bos taurus	95.13	0.00e+00	640.00
IUUC-Bci-013881	Botrytis cinerea	40.19	9.00e-22	98.20
IUUC-Bdi-014325	Brachypodium distachyon	34.91	3.00e-14	72.40
IUUC-Bol-016308	Brassica oleracea	44.66	6.00e-24	105.00
IUUC-Bra-017605	Brassica rapa	44.12	5.00e-24	105.00
IUUC-Cel-018697	Caenorhabditis elegans	54.37	4.00e-32	132.00
IUUC-Cja-018963	Callithrix jacchus	87.71	5.00e-174	603.00
IUUC-Cfa-020472	Canis familiaris	94.27	0.00e+00	640.00
IUUC-Cpo-022001	Cavia porcellus	95.70	0.00e+00	649.00
IUUC-Cre-022918	Chlamydomonas reinhardtii	30.99	2.00e-28	120.00
IUUC-Csa-023959	Chlorocebus sabaeus	95.13	5.00e-178	616.00
IUUC-Cho-024389	Choloepus hoffmanni	61.33	5.00e-28	119.00
IUUC-Cin-025688	Ciona intestinalis	47.49	2.00e-92	332.00
IUUC-Cne-026904	Cryptococcus neoformans	31.43	1.00e-14	74.70
IUUC-Cme-027280	Cyanidioschyzon merolae	40.59	9.00e-18	84.30
IUUC-Dre-027913	Danio rerio	81.38	1.00e-158	552.00
IUUC-Dno-029672	Dasypus novemcinctus	94.84	0.00e+00	640.00
IUUC-Dor-030175	Dipodomys ordii	92.50	2.00e-91	328.00
IUUC-Dse-031375	Dothistroma septosporum	37.25	3.00e-20	93.20
IUUC-Dme-031736	Drosophila melanogaster	48.50	7.00e-93	333.00
IUUC-Ete-032343	Echinops telfairi	90.54	2.00e-177	615.00
IUUC-Eca-033926	Equus caballus	94.84	0.00e+00	639.00
IUUC-Eeu-034940	Erinaceus europaeus	87.11	1.00e-174	605.00
IUUC-Fca-035491	Felis catus	93.41	0.00e+00	628.00
IUUC-Fal-037508	Ficedula albicollis	91.43	2.00e-175	607.00
IUUC-Fox-037937	Fusarium oxysporum	37.76	1.00e-18	87.40
IUUC-Fso-038091	Fusarium solani	40.78	4.00e-21	96.30
IUUC-Gmo-039427	Gadus morhua	78.80	7.00e-155	540.00
IUUC-Ggr-039724	Gaeumannomyces graminis	42.57	8.00e-21	95.10
IUUC-Gga-040998	Gallus gallus	89.40	5.00e-178	616.00
IUUC-Gac-041356	Gasterosteus aculeatus	80.23	1.00e-166	578.00
IUUC-Gma-043566	Glycine max	42.31	4.00e-23	102.00
IUUC-Ggo-044967	Gorilla gorilla	95.13	5.00e-178	616.00
IUUC-Hsa-046686	Homo sapiens	95.13	5.00e-178	616.00
IUUC-Hvu-047430	Hordeum vulgare	41.51	1.00e-20	94.00
IUUC-Itr-047929	Ictidomys tridecemlineatus	97.40	2.00e-107	380.00
IUUC-Kpa-049287	Komagataella pastoris	34.21	3.00e-14	72.80
IUUC-Lch-050597	Latimeria chalumnae	85.92	7.00e-172	596.00
IUUC-Lpe-051090	Leersia perrieri	41.51	3.00e-20	92.40
IUUC-Loc-052399	Lepisosteus oculatus	80.52	1.00e-158	551.00
IUUC-Lma-053249	Leptosphaeria maculans	29.82	7.00e-14	72.00
IUUC-Laf-053766	Loxodonta africana	95.70	0.00e+00	647.00
IUUC-Mcc-055641	Macaca mulatta	95.13	5.00e-178	616.00
IUUC-Meu-055919	Macropus eugenii	93.25	2.00e-173	600.00
IUUC-Mor-056970	Magnaporthe oryzae	43.30	5.00e-20	92.40
IUUC-Mpo-057345	Magnaporthe poae	41.24	2.00e-18	87.00
IUUC-Mtr-058436	Medicago truncatula	42.57	3.00e-23	102.00
IUUC-Mla-059037	Melampsora laricipopulina	39.09	3.00e-20	93.20
IUUC-Mga-059263	Meleagris gallopavo	91.19	4.00e-176	610.00
IUUC-Mvi-060463	Microbotryum violaceum	36.05	1.00e-15	78.20
IUUC-Mmr-060915	Microcebus murinus	94.87	0.00e+00	645.00
IUUC-Mdo-062449	Monodelphis domestica	98.85	0.00e+00	630.00
IUUC-Mmu-063151	Mus musculus	92.55	0.00e+00	626.00
IUUC-Mac-065581	Musa acuminata	40.38	6.00e-20	91.70
IUUC-Mpu-066621	Mustela putorius furo	94.27	0.00e+00	642.00
IUUC-Mlu-067336	Myotis lucifugus	94.84	0.00e+00	627.00
IUUC-Nfi-068530	Neosartorya fischeri	39.00	5.00e-19	89.40
IUUC-Ncr-068785	Neurospora crassa	39.81	2.00e-20	93.60
IUUC-Nle-069972	Nomascus leucogenys	95.13	5.00e-178	616.00
IUUC-Opr-071150	Ochotona princeps	61.89	1.00e-99	356.00
IUUC-Ont-071366	Oreochromis niloticus	79.37	5.00e-167	580.00
IUUC-Oan-073290	Ornithorhynchus anatinus	93.04	2.00e-103	367.00
IUUC-Ocu-074351	Oryctolagus cuniculus	94.84	0.00e+00	644.00
IUUC-Oba-075338	Oryza barthii	26.29	3.00e-11	62.40
IUUC-Obr-076135	Oryza brachyantha	40.57	5.00e-20	91.70
IUUC-Ogl-077182	Oryza glaberrima	40.40	6.00e-17	81.60
IUUC-Ogu-078281	Oryza glumaepatula	40.57	5.00e-20	92.00
IUUC-Oin-079068	Oryza indica	39.80	1.00e-16	80.90
IUUC-Olo-080460	Oryza longistaminata	28.26	2.00e-08	51.60
IUUC-Ome-081781	Oryza meridionalis	26.33	1.00e-17	84.30
IUUC-Oni-082517	Oryza nivara	26.04	2.00e-16	80.50
IUUC-Opu-084101	Oryza punctata	40.40	5.00e-17	81.60
IUUC-Oru-084556	Oryza rufipogon	40.40	6.00e-17	81.60
IUUC-Osa-086264	Oryza sativa	39.80	7.00e-17	81.60
IUUC-Ola-087252	Oryzias latipes	91.28	1.00e-67	248.00
IUUC-Olu-087610	Ostreococcus lucimarinus	26.09	9.00e-12	64.30
IUUC-Oga-088304	Otolemur garnettii	95.13	0.00e+00	646.00
IUUC-Oar-089734	Ovis aries	95.13	0.00e+00	640.00
IUUC-Ptr-091476	Pan troglodytes	95.13	5.00e-178	616.00
IUUC-Pan-092341	Papio anubis	95.13	5.00e-178	616.00
IUUC-Psi-093470	Pelodiscus sinensis	95.14	2.00e-180	624.00
IUUC-Pma-094143	Petromyzon marinus	64.09	2.00e-130	458.00
IUUC-Pno-095069	Phaeosphaeria nodorum	39.66	2.00e-13	70.90
IUUC-Ppa-095933	Physcomitrella patens	25.00	2.00e-13	70.10
IUUC-Pfo-096321	Poecilia formosa	79.66	5.00e-157	546.00
IUUC-Pab-098527	Pongo abelii	94.86	5.00e-155	540.00
IUUC-Pop-099323	Populus trichocarpa	26.87	5.00e-34	138.00
IUUC-Pca-101044	Procavia capensis	76.22	3.00e-135	474.00
IUUC-Ppe-101458	Prunus persica	43.27	6.00e-25	108.00
IUUC-Pva-103014	Pteropus vampyrus	89.88	1.00e-151	528.00
IUUC-Pgr-103615	Puccinia graminis	42.42	9.00e-18	84.70
IUUC-Ptt-103826	Puccinia triticina	41.18	4.00e-17	82.40
IUUC-Pte-104171	Pyrenophora teres	41.51	3.00e-19	90.10
IUUC-Pyt-104433	Pyrenophora triticirepentis	33.01	4.00e-10	59.30
IUUC-Rno-105957	Rattus norvegicus	91.40	6.00e-179	619.00
IUUC-Sce-106262	Saccharomyces cerevisiae	28.95	1.00e-10	60.50
IUUC-Spo-108175	Schizosaccharomyces pombe	29.63	2.20e-02	33.50
IUUC-Ssl-108672	Sclerotinia sclerotiorum	37.74	1.00e-20	94.40
IUUC-Smo-108973	Selaginella moellendorffii	42.11	3.00e-19	89.00
IUUC-Sly-111373	Solanum lycopersicum	39.60	6.00e-21	95.10
IUUC-Stu-112844	Solanum tuberosum	38.61	3.00e-20	92.80
IUUC-Sar-113653	Sorex araneus	80.51	4.00e-152	530.00
IUUC-Sbi-114390	Sorghum bicolor	38.68	7.00e-20	91.30
IUUC-Sre-115200	Sporisorium reilianum	43.36	3.00e-23	103.00
IUUC-Ssc-115888	Sus scrofa	94.71	6.00e-110	389.00
IUUC-Tgu-117506	Taeniopygia guttata	89.20	3.00e-176	610.00
IUUC-Tru-118063	Takifugu rubripes	79.77	2.00e-154	538.00
IUUC-Tsy-118851	Tarsius syrichta	72.41	2.00e-135	474.00
IUUC-Tni-120010	Tetraodon nigroviridis	78.98	8.00e-152	529.00
IUUC-Tca-121182	Theobroma cacao	42.31	2.00e-20	93.20
IUUC-Tre-122040	Trichoderma reesei	40.21	6.00e-18	85.50
IUUC-Tvi-122660	Trichoderma virens	44.66	6.00e-22	98.60
IUUC-Tae-124561	Triticum aestivum	41.51	1.00e-20	93.60
IUUC-Tur-126651	Triticum urartu	41.51	2.00e-20	92.80
IUUC-Tme-127184	Tuber melanosporum	48.51	5.00e-24	105.00
IUUC-Tbe-127894	Tupaia belangeri	79.00	6.00e-80	290.00
IUUC-Ttr-128264	Tursiops truncatus	86.25	5.00e-172	596.00
IUUC-Uma-129407	Ustilago maydis	44.25	2.00e-23	103.00
IUUC-Vda-130002	Verticillium dahliae	36.63	9.00e-16	78.20
IUUC-Vpa-130156	Vicugna pacos	92.44	9.00e-81	293.00
IUUC-Vvi-131479	Vitis vinifera	42.57	7.00e-22	98.20
IUUC-Xtr-132332	Xenopus tropicalis	91.18	4.00e-56	209.00
IUUC-Xma-133186	Xiphophorus maculatus	79.66	2.00e-156	545.00
IUUC-Yli-134500	Yarrowia lipolytica	32.90	4.00e-12	65.50
IUUC-Zma-135391	Zea mays	39.42	1.00e-19	90.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence