iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066127

Ensembl Protein ID

ENSMPUP00000003983.1

UniProt Accession

M3XY32; M3XY32_MUSPF

Genbank Protein ID

ENSMPUP00000003983

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01017555

Gene Name

TNK2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000004016.1	ENSMPUT00000004055.1	ENSMPUP00000003983.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	9.30e-06	25.6	1031	1060

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 9    qlveMGFdreealqaLraannnleaAveyL 38
           q++  G ++ee++ aL+++++++++A+ yL
   Q: 1031 QAMVHGVTTEECQAALQSHSWSVQRAAQYL 1060
           66777**********************998 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MLEARPLRTV TLRLPVPPEG RGLREGSAPL PGPSARSVGA MGERSAYQRL AGGEEGPQSP 60
SDLVRGSIFV EMPAARRFPG LELSFPLLAR LRRRLYTRLG SSSMQPEEGT GWLLELLSEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGGAGG CCCGGCCCCT CAGGACAGTG ACGCTGCGGC TGCCGGTGCC GCCGGAGGGG 60
CGGGGGCTGC GGGAGGGTTC TGCTCCCCTC CCTGGCCCCA GTGCCCGGAG TGTGGGTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:2000369--P:regulation of clathrin-dependent endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	98.51	0.00e+00	1412.00
IUUC-Aca-004315	Anolis carolinensis	89.71	2.00e-68	250.00
IUUC-Ame-011350	Astyanax mexicanus	64.44	0.00e+00	912.00
IUUC-Bta-012325	Bos taurus	95.78	0.00e+00	1362.00
IUUC-Cel-018130	Caenorhabditis elegans	36.47	8.00e-85	308.00
IUUC-Cja-019545	Callithrix jacchus	85.85	0.00e+00	1224.00
IUUC-Cfa-020706	Canis familiaris	95.92	0.00e+00	1402.00
IUUC-Cpo-022032	Cavia porcellus	84.82	0.00e+00	1619.00
IUUC-Csa-023936	Chlorocebus sabaeus	90.65	0.00e+00	1670.00
IUUC-Csv-026328	Ciona savignyi	59.04	4.00e-168	584.00
IUUC-Dre-028714	Danio rerio	71.45	0.00e+00	1006.00
IUUC-Dno-029525	Dasypus novemcinctus	86.89	0.00e+00	1391.00
IUUC-Dme-031778	Drosophila melanogaster	55.68	1.00e-139	490.00
IUUC-Ete-032225	Echinops telfairi	91.29	0.00e+00	846.00
IUUC-Fca-035664	Felis catus	91.39	0.00e+00	1785.00
IUUC-Gmo-039543	Gadus morhua	58.23	0.00e+00	905.00
IUUC-Gga-040241	Gallus gallus	66.73	0.00e+00	1263.00
IUUC-Gac-041457	Gasterosteus aculeatus	60.69	0.00e+00	1092.00
IUUC-Ggo-045333	Gorilla gorilla	96.32	0.00e+00	1332.00
IUUC-Hsa-046670	Homo sapiens	94.82	0.00e+00	1323.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	90.13	0.00e+00	1707.00
IUUC-Lch-049670	Latimeria chalumnae	60.59	0.00e+00	1132.00
IUUC-Loc-052870	Lepisosteus oculatus	72.33	0.00e+00	1031.00
IUUC-Laf-053782	Loxodonta africana	93.32	0.00e+00	1304.00
IUUC-Mcc-055874	Macaca mulatta	90.89	0.00e+00	1657.00
IUUC-Mga-059717	Meleagris gallopavo	69.55	0.00e+00	1327.00
IUUC-Mdo-062270	Monodelphis domestica	91.41	0.00e+00	1308.00
IUUC-Mmu-063861	Mus musculus	90.24	0.00e+00	1739.00
IUUC-Mlu-067937	Myotis lucifugus	88.43	0.00e+00	1655.00
IUUC-Nle-069298	Nomascus leucogenys	93.31	0.00e+00	1033.00
IUUC-Ont-072437	Oreochromis niloticus	67.33	0.00e+00	966.00
IUUC-Oan-073708	Ornithorhynchus anatinus	75.62	3.00e-116	412.00
IUUC-Ola-087023	Oryzias latipes	67.84	0.00e+00	943.00
IUUC-Pan-091857	Papio anubis	94.25	2.00e-93	334.00
IUUC-Psi-093401	Pelodiscus sinensis	54.95	1.00e-143	503.00
IUUC-Pfo-097455	Poecilia formosa	69.31	0.00e+00	987.00
IUUC-Rno-105586	Rattus norvegicus	89.76	0.00e+00	1725.00
IUUC-Sha-106868	Sarcophilus harrisii	84.52	0.00e+00	1571.00
IUUC-Ssc-116250	Sus scrofa	94.42	0.00e+00	1313.00
IUUC-Tgu-116592	Taeniopygia guttata	68.62	0.00e+00	1270.00
IUUC-Tru-117852	Takifugu rubripes	70.68	4.00e-176	612.00
IUUC-Tsy-119087	Tarsius syrichta	98.14	5.00e-152	531.00
IUUC-Tni-120826	Tetraodon nigroviridis	71.86	0.00e+00	1004.00
IUUC-Xtr-132069	Xenopus tropicalis	64.20	0.00e+00	1154.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence