iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117852

Ensembl Protein ID

ENSTRUP00000003678.1

UniProt Accession

H2RU61; H2RU61_TAKRU

Protein Name

Uncharacterized protein

Gene Name

tmt-opsin; tnk2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000001594.1	ENSTRUT00000003697.1	ENSTRUP00000003677.1
ENSTRUG00000001594.1	ENSTRUT00000003698.1	ENSTRUP00000003678.1
ENSTRUG00000001594.1	ENSTRUT00000003699.1	ENSTRUP00000003679.1
ENSTRUG00000001594.1	ENSTRUT00000003700.1	ENSTRUP00000003680.1
ENSTRUG00000001594.1	ENSTRUT00000003701.1	ENSTRUP00000003681.1
ENSTRUG00000001594.1	ENSTRUT00000003702.1	ENSTRUP00000003682.1
ENSTRUG00000001594.1	ENSTRUT00000003703.1	ENSTRUP00000003683.1
ENSTRUG00000001594.1	ENSTRUT00000003704.1	ENSTRUP00000003684.1
ENSTRUG00000001594.1	ENSTRUT00000003705.1	ENSTRUP00000003685.1
ENSTRUG00000001594.1	ENSTRUT00000003706.1	ENSTRUP00000003686.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	6.80e-06	27.3	964	995

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 6    kleqlveMGF.dreealqaLraannnleaAve 36
           ++eql   G  +r+e+l+ L+ +++nle+A++
   Q: 964  QVEQLFCLGLrSRSECLKLLETCDWNLEVAST 995
           58999999999*******************85 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MQCEEGTDWL LELLLEVQLQ QYFLRIRDDL NVTRLSHFDY VKNEDLEKIG MGRPGEFSFC 60
PSVRARFLFS HIPDMNCKGQ RRLWEAVKRR KAMCKRKSWM SKVFSGKRPD GKASPPPEGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCAGCA TGCAGTGTGA GGAGGGGACG GACTGGCTGC TGGAGCTGCT GCTGGAGGTG 60
CAGCTGCAGC AGTACTTCCT GAGGATCCGG GACGACCTCA ACGTCACCCG GCTGTCGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0297--G-protein coupled receptor
KW-0472--Membrane
KW-0675--Receptor
KW-1185--Reference proteome
KW-0807--Transducer
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000276--GPCR_Rhodpsn
IPR017452--GPCR_Rhodpsn_7TM
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS00237--G_PROTEIN_RECEP_F1_1
PS50262--G_PROTEIN_RECEP_F1_2
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50030--UBA

Pfam

PF00001--7tm_1
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr

PRINTS

PR00237--GPCRRHODOPSN
PR00109--TYRKINASE

SMART

SM00219--TyrKc
SM00165--UBA

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0016021--C:integral component of membrane
GO:0005524--F:ATP binding
GO:0004930--F:G-protein coupled receptor activity
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	69.06	6.00e-175	608.00
IUUC-Bta-012325	Bos taurus	70.59	0.00e+00	634.00
IUUC-Cel-018130	Caenorhabditis elegans	36.70	2.00e-70	261.00
IUUC-Cja-019545	Callithrix jacchus	64.82	2.00e-160	560.00
IUUC-Cfa-020706	Canis familiaris	70.17	0.00e+00	630.00
IUUC-Cpo-022032	Cavia porcellus	70.32	0.00e+00	629.00
IUUC-Csa-023936	Chlorocebus sabaeus	71.24	0.00e+00	628.00
IUUC-Dre-028714	Danio rerio	72.26	0.00e+00	682.00
IUUC-Dno-029525	Dasypus novemcinctus	71.67	0.00e+00	635.00
IUUC-Ete-032225	Echinops telfairi	71.43	2.00e-144	506.00
IUUC-Fca-035664	Felis catus	70.59	0.00e+00	633.00
IUUC-Gmo-039543	Gadus morhua	72.06	0.00e+00	661.00
IUUC-Gga-040241	Gallus gallus	69.33	1.00e-176	613.00
IUUC-Gac-041457	Gasterosteus aculeatus	80.99	0.00e+00	734.00
IUUC-Ggo-045333	Gorilla gorilla	71.24	0.00e+00	627.00
IUUC-Hsa-046670	Homo sapiens	71.24	0.00e+00	627.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	70.53	0.00e+00	630.00
IUUC-Lch-049670	Latimeria chalumnae	72.94	0.00e+00	655.00
IUUC-Loc-052870	Lepisosteus oculatus	69.65	0.00e+00	676.00
IUUC-Laf-053782	Loxodonta africana	66.81	5.00e-167	582.00
IUUC-Mcc-055874	Macaca mulatta	71.24	0.00e+00	628.00
IUUC-Mga-059717	Meleagris gallopavo	73.00	0.00e+00	667.00
IUUC-Mdo-062270	Monodelphis domestica	71.46	0.00e+00	633.00
IUUC-Mmu-063861	Mus musculus	70.17	0.00e+00	634.00
IUUC-Mpu-066127	Mustela putorius furo	70.59	5.00e-176	611.00
IUUC-Mlu-067937	Myotis lucifugus	71.89	0.00e+00	635.00
IUUC-Nle-069298	Nomascus leucogenys	81.48	9.00e-133	468.00
IUUC-Ont-072437	Oreochromis niloticus	60.30	0.00e+00	1210.00
IUUC-Ola-087023	Oryzias latipes	79.87	0.00e+00	721.00
IUUC-Psi-093401	Pelodiscus sinensis	48.68	9.00e-117	414.00
IUUC-Pfo-097455	Poecilia formosa	74.76	0.00e+00	712.00
IUUC-Rno-105586	Rattus norvegicus	70.17	0.00e+00	633.00
IUUC-Sha-106868	Sarcophilus harrisii	70.95	3.00e-179	622.00
IUUC-Ssc-116250	Sus scrofa	68.44	2.00e-173	603.00
IUUC-Tgu-116592	Taeniopygia guttata	73.43	0.00e+00	665.00
IUUC-Tsy-119087	Tarsius syrichta	72.44	1.00e-131	464.00
IUUC-Tni-120826	Tetraodon nigroviridis	78.88	0.00e+00	770.00
IUUC-Xtr-132069	Xenopus tropicalis	68.32	6.00e-169	588.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence