iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-087225

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04013271

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000015420.1	ENSORLT00000019302.1	ENSORLP00000019301.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.80e-118	393.7	1235	1568

Active Site

Position(s)	Description	Evidence
1536	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlld 89
           + ++++l+v+fvgE+gld++G++ref++l+s+el+np++glf+ys+nd++t+q++p s +   +h ++F+f Gr+lg+al+++ lld
   Q: 1235 DLQRSKLYVSFVGEDGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFV-DNHHEWFRFSGRILGLALVHQYLLD 1320
           456689****************************************************985.5************************ PP
   S: 90   lplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvkl 176
           ++++++fyk ll+ +++l+dle +d+e+++sl+++k+n   die++ ldltf+v+ee++g+++e+eLkpgG+ ++V ++Nk+eY+++
   Q: 1321 AFFTRPFYKGLLRIPCDLSDLEFLDEEFHQSLQWMKDN---DIEDM-LDLTFTVNEEVFGQITERELKPGGAGVSVSEKNKKEYIER 1403
           ************************************99...9***9.**************************************** PP
   S: 177  vveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerka 263
           +v++r+++g+++q+e++ +Gf+ev++ +l+s+F+++elel+i G++eid+ d++++t+y+ggy++++ +i+wFw ++e+f++e+r +
   Q: 1404 MVKWRIERGVAQQTESLVRGFYEVVDVRLVSVFDARELELVIAGTAEIDLADWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLR 1490
           *************************************************************************************** PP
   S: 264  fLqFvTgssrlPlgGfaelk....prlfvirkdasddrlPs.snTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +LqFvTg+s++P +Gfa+l+    pr+f+++k+++ ++lP+ ++TCfn+L+LP+Y+s + l+ekL +A+eet+ F+l+
   Q: 1491 LLQFVTGTSSIPYEGFASLRgsngPRRFCVEKWGKITSLPRrAHTCFNRLDLPPYPSFSMLYEKLVTAVEETSTFGLE 1568
           ****************************************55*********************************985 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

RTRSHNPPNL AVGGREHLSA PRRRSPHLRH TLSPDNLRTL AERGGAAVDP TSVVSSPVGL 60
TRANSDTDLV SSQSRSSLTA STLEHTLNRG QNLVISWDIK EEVDATDWIG LYHIDETSPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGACCCGTT CCCACAACCC ACCCAACCTG GCCGTAGGAG GCCGCGAACA TCTTTCAGCC 60
CCGCGAAGGC GCAGCCCTCA CCTTCGACAC ACTCTCAGCC CAGACAACCT GCGGACATTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR032348--HECW_N
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF16562--HECW_N
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003935	Anas platyrhynchos	72.01	0.00e+00	1377.00
IUUC-Aca-004558	Anolis carolinensis	62.90	0.00e+00	1865.00
IUUC-Ame-010893	Astyanax mexicanus	87.55	0.00e+00	1248.00
IUUC-Bta-013093	Bos taurus	82.27	0.00e+00	1321.00
IUUC-Cja-019651	Callithrix jacchus	72.69	0.00e+00	1370.00
IUUC-Cfa-021232	Canis familiaris	83.71	0.00e+00	1349.00
IUUC-Csa-023970	Chlorocebus sabaeus	72.39	0.00e+00	1360.00
IUUC-Cho-024512	Choloepus hoffmanni	75.47	0.00e+00	1150.00
IUUC-Csv-026127	Ciona savignyi	70.95	7.00e-152	530.00
IUUC-Dre-028275	Danio rerio	84.22	0.00e+00	1407.00
IUUC-Dno-029963	Dasypus novemcinctus	72.34	0.00e+00	1357.00
IUUC-Dor-030282	Dipodomys ordii	49.96	0.00e+00	978.00
IUUC-Dme-032217	Drosophila melanogaster	70.94	0.00e+00	636.00
IUUC-Eca-033978	Equus caballus	64.26	0.00e+00	1853.00
IUUC-Fca-036157	Felis catus	64.44	0.00e+00	1855.00
IUUC-Fal-037110	Ficedula albicollis	82.27	0.00e+00	1360.00
IUUC-Gmo-039291	Gadus morhua	68.78	0.00e+00	1247.00
IUUC-Gga-040821	Gallus gallus	63.67	0.00e+00	1893.00
IUUC-Gac-042456	Gasterosteus aculeatus	90.77	0.00e+00	1503.00
IUUC-Ggo-044862	Gorilla gorilla	64.42	0.00e+00	1808.00
IUUC-Hsa-046219	Homo sapiens	63.84	0.00e+00	1897.00
IUUC-Lch-050526	Latimeria chalumnae	84.21	0.00e+00	1361.00
IUUC-Loc-052648	Lepisosteus oculatus	85.12	0.00e+00	1417.00
IUUC-Laf-054005	Loxodonta africana	63.87	0.00e+00	1878.00
IUUC-Mcc-055314	Macaca mulatta	72.39	0.00e+00	1360.00
IUUC-Meu-056356	Macropus eugenii	75.20	0.00e+00	735.00
IUUC-Mga-060074	Meleagris gallopavo	83.79	0.00e+00	1286.00
IUUC-Mmr-061526	Microcebus murinus	84.30	0.00e+00	1356.00
IUUC-Mdo-063017	Monodelphis domestica	72.79	0.00e+00	1356.00
IUUC-Mmu-064165	Mus musculus	63.06	0.00e+00	1860.00
IUUC-Mpu-065835	Mustela putorius furo	84.38	0.00e+00	1301.00
IUUC-Mlu-067709	Myotis lucifugus	82.46	0.00e+00	1319.00
IUUC-Nle-069308	Nomascus leucogenys	72.03	0.00e+00	1373.00
IUUC-Ont-071918	Oreochromis niloticus	81.44	0.00e+00	2404.00
IUUC-Ocu-074775	Oryctolagus cuniculus	71.80	0.00e+00	1352.00
IUUC-Oga-088177	Otolemur garnettii	84.63	0.00e+00	1357.00
IUUC-Oar-089452	Ovis aries	73.08	0.00e+00	1359.00
IUUC-Ptr-090806	Pan troglodytes	63.78	0.00e+00	1879.00
IUUC-Pan-091838	Papio anubis	64.38	0.00e+00	1788.00
IUUC-Psi-094090	Pelodiscus sinensis	63.47	0.00e+00	1881.00
IUUC-Pfo-096520	Poecilia formosa	81.44	0.00e+00	1363.00
IUUC-Pab-098405	Pongo abelii	72.59	0.00e+00	1374.00
IUUC-Pca-100441	Procavia capensis	59.12	0.00e+00	767.00
IUUC-Pva-102324	Pteropus vampyrus	83.08	0.00e+00	1343.00
IUUC-Rno-105943	Rattus norvegicus	63.50	0.00e+00	1883.00
IUUC-Sha-106985	Sarcophilus harrisii	70.95	0.00e+00	1313.00
IUUC-Sar-113505	Sorex araneus	81.28	0.00e+00	1273.00
IUUC-Ssc-115439	Sus scrofa	58.16	2.00e-150	526.00
IUUC-Tgu-117078	Taeniopygia guttata	82.27	0.00e+00	1370.00
IUUC-Tru-118706	Takifugu rubripes	91.57	0.00e+00	1479.00
IUUC-Tni-120069	Tetraodon nigroviridis	89.03	0.00e+00	1422.00
IUUC-Ttr-128469	Tursiops truncatus	64.56	0.00e+00	1147.00
IUUC-Vpa-130498	Vicugna pacos	59.83	0.00e+00	1004.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence