iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071537

Ensembl Protein ID

ENSONIP00000011363.1

UniProt Accession

I3JR69; I3JR69_ORENI

Genbank Protein ID

ENSONIP00000011363

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AERX01040066

Gene Name

lyn; LOC100711419

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000009035.1	ENSONIT00000011372.1	ENSONIP00000011363.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.00e-16	61.1	65	121

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + v++l++yea++ d+L +kkG++++++   e+ ++W+k+++  ++k+G++P+n+v++++
   Q: 65   KIVIALFPYEAAHPDDLGFKKGEKMKIL---EEHGEWWKAKSLVNNKEGFIPSNYVAQAD 121
           689*************************...999**********************9986 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MGCMKSTLNQ GLSGGVDQKM GQHAVHSEQS RYVRDPTFNP KVNTNNSLLP GQVFQKMEEQ 60
KGVGKIVIAL FPYEAAHPDD LGFKKGEKMK ILEEHGEWWK AKSLVNNKEG FIPSNYVAQA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGAATGGG CTGCATGAAA TCCACGCTAA ATCAAGGTCT GAGTGGAGGT GTGGACCAAA 60
AAATGGGCCA ACACGCTGTG CATTCTGAAC AGTCACGCTA TGTTAGAGAC CCCACCTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0090022--P:regulation of neutrophil chemotaxis
GO:0009611--P:response to wounding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001812	Ailuropoda melanoleuca	72.76	0.00e+00	786.00
IUUC-Apl-004139	Anas platyrhynchos	73.22	0.00e+00	789.00
IUUC-Aca-004333	Anolis carolinensis	74.51	0.00e+00	801.00
IUUC-Ame-011257	Astyanax mexicanus	82.36	0.00e+00	893.00
IUUC-Bta-013257	Bos taurus	72.96	0.00e+00	788.00
IUUC-Cja-018827	Callithrix jacchus	72.76	0.00e+00	788.00
IUUC-Cfa-020816	Canis familiaris	72.57	0.00e+00	786.00
IUUC-Cpo-021423	Cavia porcellus	72.71	0.00e+00	793.00
IUUC-Csa-024244	Chlorocebus sabaeus	72.96	0.00e+00	787.00
IUUC-Dre-028518	Danio rerio	81.71	0.00e+00	885.00
IUUC-Dno-029322	Dasypus novemcinctus	73.35	0.00e+00	791.00
IUUC-Dor-030706	Dipodomys ordii	65.82	0.00e+00	698.00
IUUC-Eca-034193	Equus caballus	72.76	0.00e+00	793.00
IUUC-Fal-037273	Ficedula albicollis	73.11	0.00e+00	790.00
IUUC-Gmo-039677	Gadus morhua	81.64	0.00e+00	791.00
IUUC-Gga-040417	Gallus gallus	73.05	0.00e+00	786.00
IUUC-Gac-042490	Gasterosteus aculeatus	83.82	0.00e+00	914.00
IUUC-Ggo-045096	Gorilla gorilla	73.15	0.00e+00	790.00
IUUC-Hsa-046214	Homo sapiens	73.15	0.00e+00	790.00
IUUC-Itr-048354	Ictidomys tridecemlineatus	72.96	0.00e+00	790.00
IUUC-Lch-049991	Latimeria chalumnae	76.02	0.00e+00	809.00
IUUC-Loc-052309	Lepisosteus oculatus	81.01	0.00e+00	884.00
IUUC-Laf-053568	Loxodonta africana	72.96	0.00e+00	790.00
IUUC-Mcc-054849	Macaca mulatta	72.96	0.00e+00	787.00
IUUC-Mmr-061519	Microcebus murinus	72.37	0.00e+00	785.00
IUUC-Mdo-062090	Monodelphis domestica	68.55	0.00e+00	744.00
IUUC-Mmu-063760	Mus musculus	72.90	0.00e+00	788.00
IUUC-Mpu-065677	Mustela putorius furo	73.35	0.00e+00	791.00
IUUC-Mlu-067386	Myotis lucifugus	73.35	0.00e+00	790.00
IUUC-Nle-069742	Nomascus leucogenys	72.96	0.00e+00	786.00
IUUC-Oan-073193	Ornithorhynchus anatinus	73.69	0.00e+00	796.00
IUUC-Ocu-074501	Oryctolagus cuniculus	72.96	0.00e+00	787.00
IUUC-Ola-086726	Oryzias latipes	81.68	0.00e+00	892.00
IUUC-Oga-088069	Otolemur garnettii	72.09	0.00e+00	778.00
IUUC-Oar-090091	Ovis aries	72.96	0.00e+00	786.00
IUUC-Ptr-091409	Pan troglodytes	73.15	0.00e+00	790.00
IUUC-Pan-092268	Papio anubis	72.96	0.00e+00	787.00
IUUC-Psi-093685	Pelodiscus sinensis	74.13	0.00e+00	797.00
IUUC-Pfo-096217	Poecilia formosa	85.91	0.00e+00	933.00
IUUC-Pab-098601	Pongo abelii	72.96	0.00e+00	789.00
IUUC-Rno-105557	Rattus norvegicus	73.54	0.00e+00	793.00
IUUC-Sha-106643	Sarcophilus harrisii	73.06	0.00e+00	786.00
IUUC-Ssc-116317	Sus scrofa	68.35	0.00e+00	725.00
IUUC-Tgu-116865	Taeniopygia guttata	73.31	0.00e+00	793.00
IUUC-Tru-118284	Takifugu rubripes	83.07	0.00e+00	903.00
IUUC-Tsy-119440	Tarsius syrichta	75.32	0.00e+00	751.00
IUUC-Tni-120005	Tetraodon nigroviridis	82.19	0.00e+00	900.00
IUUC-Ttr-128481	Tursiops truncatus	64.06	0.00e+00	656.00
IUUC-Xtr-131907	Xenopus tropicalis	66.28	0.00e+00	691.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence