iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006918

UUCD1 version

UUC-ArT-00509

Ensembl Protein ID

AT3G08505.3

UniProt Accession

Q6IDS6; C3H35_ARATH

Genbank Protein ID

AEE74638.1; AEE74639.1; ANM63730.1; AAL49864.1; AAN41388.1

Protein Name

E3 ubiquitin-protein ligase makorin; RING-type E3 ubiquitin transferase makorin; Zinc finger CCCH domain-containing protein 35

Genbank Nucleotide ID

AC074395; CP002686; CP002686; AY070366; BT000988

Gene Name

MKRN; At3g08505; T8G24.6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G08505	AT3G08505.3	AT3G08505.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.80e-06	29.3	170	228

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf........kdg.plvlpCgHvfhadClqkw.....pglknssskefrCPlCr 46
           C++Cl+++        +    l++ C H f+ +C+ +w     +  +++ s+   CP+Cr
   Q: 170  CSVCLDRIlskatpgeR-KfGLLTECDHPFCIQCIRNWrssapVSGMDVNSTLRACPICR 228
           9******9988777642.2355699**********************************8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

Protein Sequence
(Fasta)

MSDRILCKFF VHGSCLKGEN CEFSHDSKDP PNNVCTFYQK RICLYGSRCR YDHVRAASNL 60
PLSSDSESLD RSISTTPSRH LQQQGDNNDG DKSSNVYCIH PREYPICSFA AAGDCPRGNQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGTGGAGGT GGAGGAAGCG CGCTCTATCT CAAAAACGTT GGGGTCTGCT TGGTCCTCAA 60
CAATTGAAAA CCGTACAAAT TCAATTTCTT CACATAAAGC TCTCTCTTCC TTCTCCATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018957--Znf_C3HC4_RING-type
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00097--zf-C3HC4
PF00642--zf-CCCH

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0003677--F:DNA binding
GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination

KEGG

ath:AT3G08505

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000297	Aegilops tauschii	48.10	3.00e-67	248.00
IUUC-Aml-001937	Ailuropoda melanoleuca	40.70	1.00e-41	163.00
IUUC-Atr-003024	Amborella trichopoda	58.86	4.00e-118	417.00
IUUC-Apl-004110	Anas platyrhynchos	40.70	3.00e-41	162.00
IUUC-Aca-005385	Anolis carolinensis	32.11	2.00e-50	192.00
IUUC-Aly-006124	Arabidopsis lyrata	95.98	6.00e-177	612.00
IUUC-Ame-011246	Astyanax mexicanus	32.61	2.00e-46	179.00
IUUC-Bta-012318	Bos taurus	32.48	2.00e-51	195.00
IUUC-Bdi-015008	Brachypodium distachyon	52.50	2.00e-89	321.00
IUUC-Bol-016162	Brassica oleracea	79.19	2.00e-134	471.00
IUUC-Bra-018102	Brassica rapa	79.81	2.00e-135	474.00
IUUC-Cel-018642	Caenorhabditis elegans	30.00	8.00e-38	150.00
IUUC-Cja-019550	Callithrix jacchus	41.21	3.00e-42	165.00
IUUC-Cfa-020166	Canis familiaris	40.70	1.00e-41	163.00
IUUC-Cpo-021887	Cavia porcellus	32.20	3.00e-51	194.00
IUUC-Cre-022707	Chlamydomonas reinhardtii	39.50	1.00e-64	238.00
IUUC-Csa-023930	Chlorocebus sabaeus	40.70	8.00e-42	164.00
IUUC-Cho-024307	Choloepus hoffmanni	40.70	1.00e-41	163.00
IUUC-Cin-025619	Ciona intestinalis	35.16	3.00e-57	214.00
IUUC-Csv-026322	Ciona savignyi	32.87	2.00e-55	208.00
IUUC-Dre-027762	Danio rerio	33.53	3.00e-55	208.00
IUUC-Dno-029666	Dasypus novemcinctus	41.21	1.00e-41	163.00
IUUC-Dor-030133	Dipodomys ordii	41.22	1.00e-28	120.00
IUUC-Dme-031705	Drosophila melanogaster	39.60	9.00e-37	147.00
IUUC-Ete-032356	Echinops telfairi	40.37	5.00e-22	97.10
IUUC-Eca-033340	Equus caballus	32.19	9.00e-51	193.00
IUUC-Eeu-035167	Erinaceus europaeus	40.70	1.00e-41	162.00
IUUC-Fca-035536	Felis catus	41.21	2.00e-41	162.00
IUUC-Fal-036881	Ficedula albicollis	33.43	9.00e-49	186.00
IUUC-Gmo-039495	Gadus morhua	40.09	2.00e-46	179.00
IUUC-Ggr-039835	Gaeumannomyces graminis	42.00	7.00e-07	48.50
IUUC-Gga-041148	Gallus gallus	41.88	4.00e-41	161.00
IUUC-Gac-041790	Gasterosteus aculeatus	33.33	1.00e-56	213.00
IUUC-Ggo-045245	Gorilla gorilla	40.70	1.00e-41	163.00
IUUC-Hsa-046589	Homo sapiens	40.70	1.00e-41	163.00
IUUC-Hvu-047044	Hordeum vulgare	50.31	2.00e-79	288.00
IUUC-Itr-048468	Ictidomys tridecemlineatus	40.54	8.00e-29	120.00
IUUC-Lch-049777	Latimeria chalumnae	32.15	2.00e-51	195.00
IUUC-Loc-052281	Lepisosteus oculatus	33.33	3.00e-51	195.00
IUUC-Laf-054551	Loxodonta africana	40.20	1.00e-40	160.00
IUUC-Mcc-055160	Macaca mulatta	40.70	2.00e-41	163.00
IUUC-Meu-056809	Macropus eugenii	40.70	1.00e-41	163.00
IUUC-Mla-059005	Melampsora laricipopulina	33.02	3.00e-22	99.40
IUUC-Mga-059767	Meleagris gallopavo	40.70	2.00e-41	162.00
IUUC-Mmr-061574	Microcebus murinus	40.70	1.00e-41	163.00
IUUC-Mdo-061974	Monodelphis domestica	33.15	2.00e-52	199.00
IUUC-Mmu-063887	Mus musculus	40.70	3.00e-41	162.00
IUUC-Mac-064993	Musa acuminata	65.05	4.00e-126	443.00
IUUC-Mpu-066756	Mustela putorius furo	40.70	2.00e-41	162.00
IUUC-Mlu-067691	Myotis lucifugus	31.89	3.00e-41	162.00
IUUC-Nle-069845	Nomascus leucogenys	40.70	1.00e-41	163.00
IUUC-Opr-070262	Ochotona princeps	40.70	2.00e-41	162.00
IUUC-Ont-071561	Oreochromis niloticus	34.14	1.00e-55	209.00
IUUC-Oan-073517	Ornithorhynchus anatinus	44.44	8.00e-10	56.60
IUUC-Ocu-074869	Oryctolagus cuniculus	39.57	2.00e-29	122.00
IUUC-Ola-086506	Oryzias latipes	36.36	1.00e-58	219.00
IUUC-Olu-087870	Ostreococcus lucimarinus	41.72	2.00e-34	137.00
IUUC-Oga-088871	Otolemur garnettii	33.33	5.00e-53	201.00
IUUC-Oar-090436	Ovis aries	40.70	7.00e-42	164.00
IUUC-Ptr-091519	Pan troglodytes	40.70	2.00e-41	162.00
IUUC-Pan-092582	Papio anubis	39.90	6.00e-40	157.00
IUUC-Psi-093168	Pelodiscus sinensis	33.53	3.00e-49	188.00
IUUC-Pfo-096075	Poecilia formosa	33.63	7.00e-56	210.00
IUUC-Pab-098764	Pongo abelii	31.08	3.00e-42	165.00
IUUC-Pop-099909	Populus trichocarpa	62.12	6.00e-129	452.00
IUUC-Pca-100903	Procavia capensis	33.24	2.00e-55	209.00
IUUC-Ppe-101248	Prunus persica	74.47	2.00e-87	315.00
IUUC-Pva-103124	Pteropus vampyrus	39.57	1.00e-29	123.00
IUUC-Rno-104976	Rattus norvegicus	40.59	2.00e-41	163.00
IUUC-Sha-107572	Sarcophilus harrisii	32.67	6.00e-48	184.00
IUUC-Smo-109483	Selaginella moellendorffii	53.00	4.00e-97	347.00
IUUC-Sit-110077	Setaria italica	51.37	2.00e-101	361.00
IUUC-Sar-113068	Sorex araneus	32.47	3.00e-49	188.00
IUUC-Sbi-114884	Sorghum bicolor	49.04	9.00e-102	362.00
IUUC-Ssc-115272	Sus scrofa	40.70	3.00e-41	162.00
IUUC-Tgu-116537	Taeniopygia guttata	31.81	1.00e-47	183.00
IUUC-Tru-118205	Takifugu rubripes	34.78	3.00e-57	214.00
IUUC-Tsy-118929	Tarsius syrichta	40.70	1.00e-41	162.00
IUUC-Tni-120744	Tetraodon nigroviridis	33.73	1.00e-55	209.00
IUUC-Tca-121675	Theobroma cacao	62.42	6.00e-114	403.00
IUUC-Tur-126806	Triticum urartu	49.13	3.00e-74	271.00
IUUC-Tme-127048	Tuber melanosporum	32.21	2.00e-18	86.30
IUUC-Tbe-128131	Tupaia belangeri	30.00	6.00e-38	150.00
IUUC-Ttr-129099	Tursiops truncatus	40.70	9.00e-42	163.00
IUUC-Vpa-130663	Vicugna pacos	39.57	1.00e-29	123.00
IUUC-Xtr-132036	Xenopus tropicalis	42.41	2.00e-41	162.00
IUUC-Xma-134162	Xiphophorus maculatus	33.63	4.00e-56	211.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence