iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.40e-16	57.6	442	494

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           v++lydye++++deLt+k+Gdv + + ++e ++gW+kg    +g+ Gl P+n+ve 
   Q: 442  VKALYDYEGAESDELTFKQGDVFEKL-EDEDEQGWCKG--RMNGRVGLYPANYVET 494
           89************************.9**********..8*************86 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSHHSDDQLL QAGSDSFWEP GNYKRTTKRI EDGYKLCNDL QQLIQERADI EKGYAKSLRT 60
WSKKWGELIE KGPEYGTTEA AWKGVLTESE RISDVHMKIK DNLCNDVNSQ IKTWQKENYH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCACATAGTT TTTTTAGTTG GCGATTCCAG ACACACACTC GAGTTGTAGT GCTTTTTTAC 60
GCTATTTTGT TATTGGTAGG TTGTCGCCCT GCTTCGGTAT GAACAAGTGC CAGAGACCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0032154--C:cleavage furrow
GO:0005768--C:endosome
GO:0030496--C:midbody
GO:0005886--C:plasma membrane
GO:0045211--C:postsynaptic membrane
GO:0071212--C:subsynaptic reticulum
GO:0008289--F:lipid binding
GO:0005543--F:phospholipid binding
GO:0036090--P:cleavage furrow ingression
GO:0007112--P:male meiosis cytokinesis
GO:0061024--P:membrane organization
GO:0000281--P:mitotic cytokinesis
GO:0007269--P:neurotransmitter secretion
GO:0045887--P:positive regulation of synaptic growth at neuromuscular junction
GO:0030100--P:regulation of endocytosis
GO:0007053--P:spindle assembly involved in male meiosis
GO:0048488--P:synaptic vesicle endocytosis

KEGG

dme:Dmel_CG33094

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	44.81	8.00e-104	369.00
IUUC-Apl-003574	Anas platyrhynchos	44.81	1.00e-99	355.00
IUUC-Aca-004251	Anolis carolinensis	42.89	2.00e-95	342.00
IUUC-Ame-011756	Astyanax mexicanus	40.48	5.00e-104	370.00
IUUC-Bta-013193	Bos taurus	43.42	8.00e-95	340.00
IUUC-Cel-018168	Caenorhabditis elegans	30.52	3.00e-64	238.00
IUUC-Cja-018756	Callithrix jacchus	43.95	2.00e-97	348.00
IUUC-Cfa-020545	Canis familiaris	44.49	7.00e-106	376.00
IUUC-Cpo-022000	Cavia porcellus	42.39	5.00e-108	384.00
IUUC-Csa-024030	Chlorocebus sabaeus	41.98	6.00e-82	296.00
IUUC-Cin-025707	Ciona intestinalis	39.51	2.00e-88	318.00
IUUC-Csv-026244	Ciona savignyi	34.04	2.00e-38	151.00
IUUC-Dre-027823	Danio rerio	67.86	7.00e-19	87.40
IUUC-Dno-029429	Dasypus novemcinctus	41.68	3.00e-92	332.00
IUUC-Dor-030122	Dipodomys ordii	47.45	1.00e-76	279.00
IUUC-Eca-033367	Equus caballus	44.19	8.00e-99	353.00
IUUC-Eeu-034821	Erinaceus europaeus	35.76	1.00e-70	259.00
IUUC-Fca-036079	Felis catus	44.49	1.00e-102	365.00
IUUC-Fal-036682	Ficedula albicollis	44.79	2.00e-99	355.00
IUUC-Gmo-039681	Gadus morhua	39.92	3.00e-83	301.00
IUUC-Gga-040717	Gallus gallus	44.79	2.00e-98	352.00
IUUC-Gac-041445	Gasterosteus aculeatus	41.22	2.00e-85	308.00
IUUC-Ggo-044841	Gorilla gorilla	43.87	8.00e-95	340.00
IUUC-Hsa-046411	Homo sapiens	43.78	5.00e-95	340.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	44.40	1.00e-95	343.00
IUUC-Lch-050070	Latimeria chalumnae	40.82	1.00e-95	342.00
IUUC-Loc-051975	Lepisosteus oculatus	41.86	8.00e-105	373.00
IUUC-Laf-053839	Loxodonta africana	42.44	1.00e-99	356.00
IUUC-Mcc-055783	Macaca mulatta	43.45	1.00e-94	339.00
IUUC-Meu-056348	Macropus eugenii	41.03	3.00e-87	315.00
IUUC-Mga-059216	Meleagris gallopavo	41.65	5.00e-105	374.00
IUUC-Mmr-060827	Microcebus murinus	44.40	6.00e-99	353.00
IUUC-Mdo-062600	Monodelphis domestica	44.15	4.00e-81	294.00
IUUC-Mmu-064109	Mus musculus	44.61	2.00e-100	358.00
IUUC-Mpu-066591	Mustela putorius furo	44.81	9.00e-104	369.00
IUUC-Mlu-067826	Myotis lucifugus	44.31	1.00e-102	365.00
IUUC-Nle-069797	Nomascus leucogenys	43.87	4.00e-95	340.00
IUUC-Opr-071050	Ochotona princeps	41.81	2.00e-73	268.00
IUUC-Ont-072188	Oreochromis niloticus	44.06	2.00e-100	358.00
IUUC-Oan-073256	Ornithorhynchus anatinus	42.81	2.00e-79	288.00
IUUC-Ocu-074425	Oryctolagus cuniculus	44.17	2.00e-95	341.00
IUUC-Ola-087188	Oryzias latipes	48.84	4.00e-67	248.00
IUUC-Oga-089009	Otolemur garnettii	42.74	1.00e-97	349.00
IUUC-Oar-089806	Ovis aries	43.00	2.00e-94	338.00
IUUC-Ptr-091111	Pan troglodytes	43.96	2.00e-94	338.00
IUUC-Pan-091749	Papio anubis	43.10	2.00e-92	332.00
IUUC-Psi-093704	Pelodiscus sinensis	43.87	2.00e-101	362.00
IUUC-Pfo-097528	Poecilia formosa	45.33	6.00e-67	247.00
IUUC-Pab-098202	Pongo abelii	40.41	1.00e-85	309.00
IUUC-Pca-100881	Procavia capensis	40.16	3.00e-85	308.00
IUUC-Pva-102649	Pteropus vampyrus	44.40	5.00e-97	347.00
IUUC-Rno-105431	Rattus norvegicus	44.63	3.00e-105	374.00
IUUC-Sha-106641	Sarcophilus harrisii	44.05	1.00e-104	372.00
IUUC-Sar-113461	Sorex araneus	40.70	1.00e-92	332.00
IUUC-Ssc-115349	Sus scrofa	43.78	6.00e-96	343.00
IUUC-Tgu-116876	Taeniopygia guttata	44.79	2.00e-98	351.00
IUUC-Tru-118248	Takifugu rubripes	45.86	5.00e-72	263.00
IUUC-Tsy-118901	Tarsius syrichta	38.15	2.00e-56	212.00
IUUC-Tni-120120	Tetraodon nigroviridis	40.04	6.00e-92	330.00
IUUC-Ttr-129069	Tursiops truncatus	39.96	1.00e-81	296.00
IUUC-Vpa-130760	Vicugna pacos	45.51	2.00e-44	172.00
IUUC-Xtr-132925	Xenopus tropicalis	43.39	1.00e-106	379.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence