iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040561

UUCD1 version

UUC-GaG-00778

Ensembl Protein ID

ENSGALP00000020504.4

UniProt Accession

A0A0A0MQ50; A0A0A0MQ50_CHICK

Genbank Protein ID

ENSGALP00000020504

Protein Name

WD repeat, SAM and U-box domain-containing protein 1

Genbank Nucleotide ID

AADN04000046

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000012574.5	ENSGALT00000020533.4	ENSGALP00000020504.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.40e-25	87.9	405	476
E3 adaptor/Cullin RING/DCX/DWD	2.70e-39	131.8	11	42
UBD/Beta-Prp	2.60e-52	178.2	4	217

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           vp+eflCpI+ elM+dPv++++G++y+++++e w++++++++P+t+ pl +  l+Pn tl+  i++w+e+++
   Q: 405  VPDEFLCPITRELMKDPVIAADGYSYEKEAMENWISNNRRSSPMTNLPLPSLVLTPNRTLKMAISRWLETQQ 476
           8********************************************************************987 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtg 33
           H+d+v+c+afs+  l+++s D+ti++++l ++
   Q: 11   HSDDVNCCAFSSSCLATCSLDKTIRIYSLNDF 42
           **********44689*************9776 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdls..tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcle 130
           l+++l +h++ v+++ fs++   l+t+s D+ti++++l+  t  + + lkgh++ v ++ fspsg++l+s s d    +wd++ g  l 
   Q: 4    LIHTLTDHSDDVNCCAFSSS--CLATCSLDKTIRIYSLNdfTELPYSPLKGHTYAVHCCCFSPSGHTLASCSTDGATIIWDTSDGRMLA 90
           67777788888888888877..7788888888888877744444566777888888888888877888888888877788888887777 PP
   S: 131  etlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            +++++ + v++ +++p++ +lvsG++D+ v lW++ ++k  r     +++s    +f++ g+++v+gs  g++++wd +   c+   +
   Q: 91   VLEQPTGSPVRVCRFSPESTYLVSGAADGSVVLWNVHSMKFYRSGNV-KDGSLVACAFSPGGNFFVTGSSCGDLTVWDDKMR-CLCNEK 177
           56666666777777888778888888888888888877777777765.7777777778888888888888888888887543.666667 PP
   S: 220  ghtdnvksvrfs..........pnderlvsgssDgsiriW 249
           +h+  v++ + s          +    ++s+++D+ i++W
   Q: 178  AHDLGVTCCDISshpvsdgehaSGCFQMASCGQDNKIKVW 217
           7775555555554444444333566677777777777777 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MATLIHTLTD HSDDVNCCAF SSSCLATCSL DKTIRIYSLN DFTELPYSPL KGHTYAVHCC 60
CFSPSGHTLA SCSTDGATII WDTSDGRMLA VLEQPTGSPV RVCRFSPEST YLVSGAADGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGCGGGCC GCGGGCCCTC AGCGCAGCTC TGCTTCTGCG GCCTGCCGGT CCAGCTGCCC 60
GTGGAGTGCC GCTGGTAAAG CTGCCCATGA GCTGAGCAAC TGCAGCGGGT GAGCAGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

gga:424331

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	75.26	0.00e+00	756.00
IUUC-Apl-003529	Anas platyrhynchos	85.53	0.00e+00	857.00
IUUC-Aca-004257	Anolis carolinensis	68.23	0.00e+00	683.00
IUUC-Ame-011357	Astyanax mexicanus	49.49	7.00e-112	397.00
IUUC-Bta-013032	Bos taurus	73.22	0.00e+00	730.00
IUUC-Cja-018743	Callithrix jacchus	73.58	0.00e+00	742.00
IUUC-Cfa-021197	Canis familiaris	74.84	0.00e+00	753.00
IUUC-Cpo-022279	Cavia porcellus	73.38	0.00e+00	735.00
IUUC-Csa-023954	Chlorocebus sabaeus	74.63	0.00e+00	749.00
IUUC-Cho-025083	Choloepus hoffmanni	60.95	7.00e-127	446.00
IUUC-Cin-025786	Ciona intestinalis	36.42	2.00e-85	309.00
IUUC-Dre-028087	Danio rerio	53.96	4.00e-138	484.00
IUUC-Dno-028919	Dasypus novemcinctus	74.42	0.00e+00	743.00
IUUC-Dor-031112	Dipodomys ordii	71.70	0.00e+00	716.00
IUUC-Ete-032405	Echinops telfairi	72.89	1.00e-148	518.00
IUUC-Eca-033254	Equus caballus	72.96	0.00e+00	733.00
IUUC-Eeu-034545	Erinaceus europaeus	69.81	0.00e+00	682.00
IUUC-Fca-035482	Felis catus	75.26	0.00e+00	756.00
IUUC-Fal-036976	Ficedula albicollis	68.38	0.00e+00	634.00
IUUC-Gmo-039213	Gadus morhua	54.33	9.00e-134	469.00
IUUC-Gac-041471	Gasterosteus aculeatus	56.03	2.00e-132	465.00
IUUC-Ggo-045503	Gorilla gorilla	74.42	0.00e+00	746.00
IUUC-Hsa-045910	Homo sapiens	74.63	0.00e+00	748.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	72.49	5.00e-164	570.00
IUUC-Loc-052307	Lepisosteus oculatus	56.97	2.00e-166	578.00
IUUC-Laf-053587	Loxodonta africana	73.17	0.00e+00	735.00
IUUC-Mcc-055679	Macaca mulatta	74.42	0.00e+00	746.00
IUUC-Meu-055962	Macropus eugenii	64.36	9.00e-172	596.00
IUUC-Mga-059652	Meleagris gallopavo	93.50	0.00e+00	934.00
IUUC-Mmr-060943	Microcebus murinus	71.40	0.00e+00	718.00
IUUC-Mdo-062592	Monodelphis domestica	73.12	0.00e+00	738.00
IUUC-Mmu-063577	Mus musculus	70.02	0.00e+00	696.00
IUUC-Mpu-066422	Mustela putorius furo	74.42	0.00e+00	754.00
IUUC-Mlu-067250	Myotis lucifugus	73.58	0.00e+00	736.00
IUUC-Nle-069517	Nomascus leucogenys	74.42	0.00e+00	746.00
IUUC-Opr-070776	Ochotona princeps	72.96	0.00e+00	722.00
IUUC-Ont-071821	Oreochromis niloticus	57.11	2.00e-144	504.00
IUUC-Oan-073706	Ornithorhynchus anatinus	75.00	0.00e+00	757.00
IUUC-Ocu-074766	Oryctolagus cuniculus	65.90	0.00e+00	645.00
IUUC-Ola-086531	Oryzias latipes	55.27	5.00e-137	480.00
IUUC-Oga-088388	Otolemur garnettii	72.33	0.00e+00	734.00
IUUC-Oar-089748	Ovis aries	73.22	0.00e+00	732.00
IUUC-Ptr-090616	Pan troglodytes	74.47	0.00e+00	743.00
IUUC-Pan-091769	Papio anubis	72.97	8.00e-150	522.00
IUUC-Psi-093334	Pelodiscus sinensis	76.97	0.00e+00	739.00
IUUC-Pma-094383	Petromyzon marinus	49.81	2.00e-133	469.00
IUUC-Pfo-096832	Poecilia formosa	49.18	2.00e-132	465.00
IUUC-Pab-098139	Pongo abelii	72.82	4.00e-171	593.00
IUUC-Pca-100523	Procavia capensis	73.10	2.00e-139	488.00
IUUC-Pva-102286	Pteropus vampyrus	74.00	0.00e+00	718.00
IUUC-Rno-104831	Rattus norvegicus	70.23	0.00e+00	704.00
IUUC-Sha-107499	Sarcophilus harrisii	74.63	0.00e+00	751.00
IUUC-Sar-113389	Sorex araneus	72.75	0.00e+00	708.00
IUUC-Tgu-116769	Taeniopygia guttata	82.60	0.00e+00	816.00
IUUC-Tru-118774	Takifugu rubripes	52.87	4.00e-135	474.00
IUUC-Tsy-119595	Tarsius syrichta	64.56	2.00e-146	511.00
IUUC-Tni-119850	Tetraodon nigroviridis	55.06	2.00e-139	488.00
IUUC-Tbe-127938	Tupaia belangeri	68.20	7.00e-119	419.00
IUUC-Ttr-128193	Tursiops truncatus	74.12	1.00e-179	622.00
IUUC-Vpa-130275	Vicugna pacos	74.84	0.00e+00	748.00
IUUC-Xtr-131982	Xenopus tropicalis	61.54	6.00e-169	586.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence