iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093969

Ensembl Protein ID

ENSPSIP00000002701.1

UniProt Accession

K7F3U1; K7F3U1_PELSI

Genbank Protein ID

ENSPSIP00000002701

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01054446

Gene Name

HACE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000002633.1	ENSPSIT00000002710.1	ENSPSIP00000002701.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.40e-118	396.2	575	904

Active Site

Position(s)	Description	Evidence
875	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           ++lk+ + v+f gEeg+++ Gv re+++ ls+e+ npd+ lf++s+ d +t+qpn++s + np+hl++F+f+G++lg+al +++l+++ 
   Q: 575  AKLKQGIAVRFHGEEGMGQ-GVVREWFDILSNEIVNPDYALFTQSA-DGTTFQPNSNSSV-NPDHLNYFRFAGQILGLALNHRQLVNIY 660
           679999*************.**********************6666.67788*******9.89************************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           +++sfyk++lg +++++d++++dpe++k+l++i++n   di++lgl+ltfsv+++++g ++e+ LkpgG++i Vt++Nk eYv+lv+e+
   Q: 661  FTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDN---DISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQDNKAEYVQLVTEL 746
           **********************************99...************************************************** PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           r+++ i+ q++af +Gf+  ip++l++lF+e elell++G++eidv+d+ k+t+y++gy++++p+iqwFw+v+ee+++eer  +LqFvT
   Q: 747  RMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWDVVEELTQEERVLLLQFVT 835
           ***************************************************************************************** PP
   S: 270  gssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kg 332
           gssr+P+gGfa ++     + f+i     +++ lP+s+TC+n+LkLPeY+skeilk++Ll+A + +  g
   Q: 836  GSSRVPHGGFAHIMggsgLQNFTIAAvPYTPNLLPTSSTCINMLKLPEYPSKEILKNRLLVALHCGsYG 904
           ******************8888888868888********************************986555 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MPMVMADQHR SVSELLSNSK FDVNYAFGRV KRSLLHIAAN CGSVECLVLL LKKGANPNYQ 60
DISGCTPLHL AARNGQKKCM SKLLEYSADV NICNNEGLTA IHWLAVNGRT ELLHDLVQHV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCAATGG TTATGGCTGA CCAGCACAGG TGAGTATTTT CTCCTATAGC TTTGTATGTA 60
AATTACTACT TTTTAAATTA CCTTATTTTT AAGGTTGCAA CTAATTAGTC TGTGTAACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000569--HECT_dom

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50237--HECT

Pfam

PF12796--Ank_2
PF00632--HECT

PRINTS

PR01415--ANKYRIN

SMART

SM00248--ANK
SM00119--HECTc

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0000139--C:Golgi membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0007030--P:Golgi organization
GO:0061025--P:membrane fusion
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030334--P:regulation of cell migration

KEGG

pss:102452124

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	40.36	1.00e-82	303.00
IUUC-Aml-001490	Ailuropoda melanoleuca	90.56	0.00e+00	1694.00
IUUC-Atr-002582	Amborella trichopoda	43.18	2.00e-98	355.00
IUUC-Apl-003400	Anas platyrhynchos	95.91	0.00e+00	1285.00
IUUC-Aca-005375	Anolis carolinensis	89.43	0.00e+00	1701.00
IUUC-Aly-006157	Arabidopsis lyrata	44.32	1.00e-99	359.00
IUUC-Ath-007160	Arabidopsis thaliana	42.53	2.00e-94	342.00
IUUC-Ani-009412	Aspergillus nidulans	42.79	9.00e-98	353.00
IUUC-Ame-011847	Astyanax mexicanus	85.01	0.00e+00	1599.00
IUUC-Bta-012831	Bos taurus	91.19	0.00e+00	1709.00
IUUC-Bdi-014884	Brachypodium distachyon	42.76	5.00e-97	350.00
IUUC-Bol-016533	Brassica oleracea	51.99	5.00e-78	283.00
IUUC-Bra-016726	Brassica rapa	44.32	4.00e-100	361.00
IUUC-Cja-019160	Callithrix jacchus	91.20	0.00e+00	1709.00
IUUC-Cfa-020346	Canis familiaris	90.86	0.00e+00	1703.00
IUUC-Cpo-021766	Cavia porcellus	90.42	0.00e+00	1703.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	43.12	5.00e-98	350.00
IUUC-Csa-023768	Chlorocebus sabaeus	90.86	0.00e+00	1707.00
IUUC-Cho-024688	Choloepus hoffmanni	85.65	0.00e+00	1110.00
IUUC-Cin-025417	Ciona intestinalis	51.07	2.00e-139	489.00
IUUC-Csv-025993	Ciona savignyi	44.77	1.00e-137	483.00
IUUC-Cne-027095	Cryptococcus neoformans	39.36	1.00e-80	296.00
IUUC-Cme-027267	Cyanidioschyzon merolae	41.76	2.00e-85	311.00
IUUC-Dre-027819	Danio rerio	82.60	0.00e+00	1565.00
IUUC-Dno-029027	Dasypus novemcinctus	90.91	0.00e+00	1706.00
IUUC-Dor-030327	Dipodomys ordii	84.14	0.00e+00	1534.00
IUUC-Ete-032966	Echinops telfairi	84.58	0.00e+00	1575.00
IUUC-Eca-034339	Equus caballus	90.86	0.00e+00	1706.00
IUUC-Eeu-034544	Erinaceus europaeus	79.81	8.00e-146	510.00
IUUC-Fca-035617	Felis catus	88.84	0.00e+00	1241.00
IUUC-Fal-036687	Ficedula albicollis	96.26	0.00e+00	1818.00
IUUC-Gmo-039508	Gadus morhua	88.38	0.00e+00	837.00
IUUC-Gga-040845	Gallus gallus	96.70	0.00e+00	1847.00
IUUC-Gac-041894	Gasterosteus aculeatus	81.88	0.00e+00	1539.00
IUUC-Gma-044216	Glycine max	44.09	2.00e-100	362.00
IUUC-Ggo-044465	Gorilla gorilla	87.60	0.00e+00	1632.00
IUUC-Hsa-045731	Homo sapiens	91.08	0.00e+00	1711.00
IUUC-Hvu-047697	Hordeum vulgare	42.53	4.00e-96	347.00
IUUC-Itr-048716	Ictidomys tridecemlineatus	91.41	0.00e+00	1710.00
IUUC-Lch-050436	Latimeria chalumnae	86.76	0.00e+00	1635.00
IUUC-Lpe-051550	Leersia perrieri	42.99	4.00e-98	354.00
IUUC-Loc-052287	Lepisosteus oculatus	87.65	0.00e+00	1667.00
IUUC-Lma-053159	Leptosphaeria maculans	40.35	3.00e-94	342.00
IUUC-Laf-053846	Loxodonta africana	91.30	0.00e+00	1716.00
IUUC-Mcc-055845	Macaca mulatta	90.97	0.00e+00	1710.00
IUUC-Meu-056060	Macropus eugenii	88.92	0.00e+00	682.00
IUUC-Mtr-057633	Medicago truncatula	42.55	1.00e-101	365.00
IUUC-Mga-059935	Meleagris gallopavo	93.06	0.00e+00	1759.00
IUUC-Mmr-060960	Microcebus murinus	91.41	0.00e+00	1715.00
IUUC-Mdo-061851	Monodelphis domestica	94.93	0.00e+00	1811.00
IUUC-Mmu-063657	Mus musculus	90.53	0.00e+00	1705.00
IUUC-Mac-065229	Musa acuminata	43.18	3.00e-98	355.00
IUUC-Mpu-066161	Mustela putorius furo	97.49	0.00e+00	820.00
IUUC-Mlu-067354	Myotis lucifugus	90.43	0.00e+00	1667.00
IUUC-Nle-069112	Nomascus leucogenys	90.97	0.00e+00	1711.00
IUUC-Opr-070686	Ochotona princeps	87.47	0.00e+00	800.00
IUUC-Ont-072398	Oreochromis niloticus	82.04	0.00e+00	1548.00
IUUC-Oan-073194	Ornithorhynchus anatinus	90.09	0.00e+00	1693.00
IUUC-Ocu-074397	Oryctolagus cuniculus	80.83	0.00e+00	1465.00
IUUC-Oba-075757	Oryza barthii	42.76	4.00e-97	351.00
IUUC-Obr-076553	Oryza brachyantha	43.21	7.00e-98	353.00
IUUC-Ogl-077520	Oryza glaberrima	42.76	4.00e-97	351.00
IUUC-Ogu-078278	Oryza glumaepatula	42.76	4.00e-97	351.00
IUUC-Oin-079767	Oryza indica	42.76	4.00e-97	351.00
IUUC-Olo-080380	Oryza longistaminata	42.60	9.00e-96	346.00
IUUC-Ome-081925	Oryza meridionalis	42.60	1.00e-95	346.00
IUUC-Oni-082619	Oryza nivara	42.76	4.00e-97	351.00
IUUC-Opu-083684	Oryza punctata	42.60	9.00e-96	346.00
IUUC-Oru-084501	Oryza rufipogon	42.76	4.00e-97	351.00
IUUC-Osa-086251	Oryza sativa	42.60	3.00e-97	349.00
IUUC-Ola-086777	Oryzias latipes	82.22	0.00e+00	1528.00
IUUC-Oga-088684	Otolemur garnettii	91.20	0.00e+00	1708.00
IUUC-Oar-089428	Ovis aries	90.50	0.00e+00	1675.00
IUUC-Ptr-090529	Pan troglodytes	90.97	0.00e+00	1709.00
IUUC-Pan-091702	Papio anubis	90.86	0.00e+00	1707.00
IUUC-Pno-094871	Phaeosphaeria nodorum	40.35	4.00e-94	341.00
IUUC-Ppa-095834	Physcomitrella patens	43.18	8.00e-98	353.00
IUUC-Pfo-097364	Poecilia formosa	82.93	0.00e+00	1563.00
IUUC-Pab-098574	Pongo abelii	91.08	0.00e+00	1711.00
IUUC-Pop-099468	Populus trichocarpa	44.09	2.00e-100	362.00
IUUC-Pca-100525	Procavia capensis	69.34	1.00e-166	580.00
IUUC-Ppe-101641	Prunus persica	43.64	2.00e-99	358.00
IUUC-Pva-102365	Pteropus vampyrus	79.63	0.00e+00	1441.00
IUUC-Pgr-103465	Puccinia graminis	40.37	9.00e-100	360.00
IUUC-Ptt-103813	Puccinia triticina	37.86	3.00e-89	325.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	40.49	4.00e-95	344.00
IUUC-Rno-105153	Rattus norvegicus	90.53	0.00e+00	1704.00
IUUC-Sha-107319	Sarcophilus harrisii	94.82	0.00e+00	1804.00
IUUC-Smo-109640	Selaginella moellendorffii	42.60	7.00e-98	353.00
IUUC-Sit-110598	Setaria italica	43.44	1.00e-97	352.00
IUUC-Sly-111706	Solanum lycopersicum	44.32	2.00e-100	362.00
IUUC-Stu-112894	Solanum tuberosum	34.47	2.00e-54	207.00
IUUC-Sar-113449	Sorex araneus	69.95	2.00e-157	549.00
IUUC-Sbi-114042	Sorghum bicolor	43.74	6.00e-98	353.00
IUUC-Sre-114958	Sporisorium reilianum	45.21	4.00e-108	385.00
IUUC-Ssc-115865	Sus scrofa	90.86	0.00e+00	1707.00
IUUC-Tgu-117225	Taeniopygia guttata	96.04	0.00e+00	1837.00
IUUC-Tru-118026	Takifugu rubripes	81.26	0.00e+00	1540.00
IUUC-Tsy-119407	Tarsius syrichta	78.41	0.00e+00	1413.00
IUUC-Tni-120234	Tetraodon nigroviridis	80.32	0.00e+00	1222.00
IUUC-Tca-121479	Theobroma cacao	43.86	2.00e-101	365.00
IUUC-Tae-125214	Triticum aestivum	42.04	1.00e-95	345.00
IUUC-Tbe-127708	Tupaia belangeri	78.19	0.00e+00	803.00
IUUC-Ttr-128667	Tursiops truncatus	90.97	0.00e+00	1707.00
IUUC-Uma-129355	Ustilago maydis	45.88	7.00e-109	387.00
IUUC-Vpa-130200	Vicugna pacos	90.64	0.00e+00	1694.00
IUUC-Vvi-131078	Vitis vinifera	44.09	4.00e-101	364.00
IUUC-Xtr-132176	Xenopus tropicalis	89.34	0.00e+00	1707.00
IUUC-Xma-133936	Xiphophorus maculatus	82.64	0.00e+00	950.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence