iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090756

UUCD1 version

UUC-PaT-00681

Ensembl Protein ID

ENSPTRP00000033816.4

UniProt Accession

H2QVG2; H2QVG2_PANTR

Genbank Protein ID

JAA12595.1; JAA22482.1

Protein Name

Tripartite motif containing 24

Genbank Nucleotide ID

AC187728; GABD01010618

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000019742.5	ENSPTRT00000036575.4	ENSPTRP00000033816.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-09	38.1	827	871

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gge    l++CekC ++fH  C+ ++  +++p+ e wiC+ Cr
   Q: 827  DWCAVCQNGGE----LLCCEKCPKVFHLSCHVPT-LTNFPSGE-WICTFCR 871
           79*********....*******************.*******8.******8 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MEVAVEKAVA AAAAASAAAS GGPSAAPSGE NEAESRQGPD SERGGEAARL NLLDTCAVCH 60
QNIQSRAPKL LPCLHSFCQR CLPAPQRYLM LPAPMLGSAE TPPPVPAPGS PVSGSSPFAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACAGATACC CTCCTTCCGG CCGCGCCACT CGGGAGGCGG ATCCCGTGGG CCTGAGGAGG 60
CTTCCCCCGC CCGGCTTGCT TTCCCTCCCT CGCTGGCGCT GCCGCGAGTC CACCGAGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

KEGG

ptr:107971692

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	97.21	0.00e+00	1697.00
IUUC-Apl-003697	Anas platyrhynchos	80.90	0.00e+00	1298.00
IUUC-Bta-013282	Bos taurus	96.39	0.00e+00	1736.00
IUUC-Cja-018920	Callithrix jacchus	98.43	0.00e+00	1782.00
IUUC-Cfa-020984	Canis familiaris	97.85	0.00e+00	1752.00
IUUC-Cpo-022035	Cavia porcellus	95.80	0.00e+00	1607.00
IUUC-Csa-024208	Chlorocebus sabaeus	99.71	0.00e+00	1805.00
IUUC-Cho-024413	Choloepus hoffmanni	65.18	1.00e-161	563.00
IUUC-Dno-029145	Dasypus novemcinctus	97.52	0.00e+00	1630.00
IUUC-Dor-030396	Dipodomys ordii	93.53	0.00e+00	1218.00
IUUC-Ete-032414	Echinops telfairi	87.30	0.00e+00	917.00
IUUC-Eca-033489	Equus caballus	97.95	0.00e+00	1606.00
IUUC-Eeu-034654	Erinaceus europaeus	93.83	0.00e+00	762.00
IUUC-Fca-035844	Felis catus	93.77	0.00e+00	1474.00
IUUC-Fal-036735	Ficedula albicollis	80.43	0.00e+00	1313.00
IUUC-Gga-041124	Gallus gallus	79.02	0.00e+00	1372.00
IUUC-Ggo-044542	Gorilla gorilla	99.90	0.00e+00	1802.00
IUUC-Hsa-046785	Homo sapiens	100.00	0.00e+00	1801.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	97.29	0.00e+00	1697.00
IUUC-Laf-054279	Loxodonta africana	94.09	0.00e+00	1679.00
IUUC-Mcc-055668	Macaca mulatta	99.71	0.00e+00	1806.00
IUUC-Meu-056195	Macropus eugenii	77.78	0.00e+00	796.00
IUUC-Mga-059272	Meleagris gallopavo	80.36	0.00e+00	1286.00
IUUC-Mmr-060936	Microcebus murinus	95.90	0.00e+00	1752.00
IUUC-Mdo-062848	Monodelphis domestica	88.96	0.00e+00	1592.00
IUUC-Mmu-063598	Mus musculus	92.32	0.00e+00	1693.00
IUUC-Mpu-066272	Mustela putorius furo	97.81	0.00e+00	1618.00
IUUC-Mlu-067958	Myotis lucifugus	94.95	0.00e+00	1586.00
IUUC-Nle-069375	Nomascus leucogenys	99.81	0.00e+00	1806.00
IUUC-Opr-070836	Ochotona princeps	82.74	0.00e+00	668.00
IUUC-Oan-073393	Ornithorhynchus anatinus	80.39	0.00e+00	1013.00
IUUC-Ocu-074873	Oryctolagus cuniculus	94.97	0.00e+00	1562.00
IUUC-Oga-088692	Otolemur garnettii	95.62	0.00e+00	1737.00
IUUC-Oar-090160	Ovis aries	96.99	0.00e+00	1592.00
IUUC-Pan-091719	Papio anubis	99.62	0.00e+00	1801.00
IUUC-Psi-093433	Pelodiscus sinensis	81.47	0.00e+00	1348.00
IUUC-Pab-098599	Pongo abelii	98.48	0.00e+00	1775.00
IUUC-Pca-100540	Procavia capensis	88.27	0.00e+00	971.00
IUUC-Pva-102478	Pteropus vampyrus	90.29	0.00e+00	1568.00
IUUC-Rno-105478	Rattus norvegicus	78.00	0.00e+00	651.00
IUUC-Sha-106740	Sarcophilus harrisii	85.19	0.00e+00	1374.00
IUUC-Sar-113615	Sorex araneus	94.64	0.00e+00	1399.00
IUUC-Tgu-117368	Taeniopygia guttata	77.57	0.00e+00	1389.00
IUUC-Tsy-118904	Tarsius syrichta	98.49	0.00e+00	1639.00
IUUC-Tbe-127354	Tupaia belangeri	83.15	0.00e+00	717.00
IUUC-Ttr-128983	Tursiops truncatus	92.84	0.00e+00	1189.00
IUUC-Vpa-130420	Vicugna pacos	95.37	0.00e+00	1573.00
IUUC-Vvi-131561	Vitis vinifera	47.17	3.00e-12	67.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence